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1.

Objective

The aim of this study was to define histopathological features of giant cell tumor of bone, especially accompanying fibrohistiocytic or aneurysmal bone cyst like components, in the light of our institutions experience.

Methods

A total of 120 cases (64 females and 56 males; mean age: 36.2 (12–80)) with ‘GCT’ diagnosed between the years 1996–2016 were included in this retrospective analysis. Cases were evaluated according to clinical features such as age, gender, localization, recurrence, metastasis and histopathological features.

Results

Tumors were localized most frequently at proximal tibia and distal femur, respectively. In 11 cases areas rich in fibrohistiocytic component and in 20 cases aneurysmal bone cyst like component were observed. In 2 cases both components were present. Twenty three cases recurred. In 1 case which was primarily located at calcaneus, tumor metastasized to lung 4 years later during follow-up.

Conclusion

GCT can be confused with other tumor or tumor-like lesions involving giant cells. Secondary changes such as fibrohistiocytic or aneurysmal bone cyst-like components and coagulation necrosis were frequently seen in conventional giant cell tumor of bone. For tumors having prominent fibrohistiocytic and/or aneurysmal bone cyst-like components, in order to detect characteristic areas representing GCT, additional sampling is essential. Although secondary histopathological changes do not appear to affect clinical outcome, these features are important in differential diagnosis. Approximately one fifth of GCT cases show recurrence and sacrum and foot bones were the most frequent sites for recurrence.

Level of evidence

Level IV, diagnostic study.  相似文献   
2.
Abstract

Data on eating disorders in women with PCOS is insufficient. The objective of this case study was to examine the hypothesis that women with PCOS exhibit more impaired eating than healthy women. Women diagnosed with PCOS under the 2003 Rotterdam Diagnostic Criteria (n?=?40) were compared with a healthy control group (n?=?40). The groups also were divided into two as normal body weight and overweight/obese. The Eating Disorders Assessment Questionnaire (EDE-Q) and the Three Factor Eating Questionnaire (TFEQ-R21), were completed by all participants in order to evaluate eating behaviors in addition to eating disorders. Among the overweight/obese group, the average total and subscale scores of the EDE-Q as well as the total and sub-factor scores of the TFEQ-R21 were higher in women with PCOS compared to controls (p?<?.05). However, this statistically significant result was not shown among the women with normal weight (p?>?.05). In comparison to the controls, the PCOS women displayed higher values of the tool scores indicating abnormal restraint eating, body shape concern and weight concern subscale scores (p?<?.05). This result suggests that the evaluation of eating disorders should be added to routine screening and the monitoring of women with PCOS.  相似文献   
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This clinical report describes the treatment of excessive gingival recession involving maxillary right and left central incisors in a 30-year-old woman. The loss of the gingival soft tissue caused an increase in crown length. Gingiva-colored partial porcelain laminate veneers were applied to imitate the lost gingiva and to provide a natural anatomical tooth length. This method may be a minimally invasive alternative treatment method for gingival soft tissue loss, providing esthetic results and patient satisfaction.  相似文献   
7.
In this study, marginal adaptations of different copings fabricated with CAD/CAM or MAD/CAM were analysed. Celay and Zirkonzahn groups were fabricated by MAD/CAM, LAVA and DC-Zircon groups were fabricated by CAD/CAM. Casting metal copings were used as the control group. An implant abutment that was embedded in octagonal acrylic block was used to prepare the copings. Sixteen previously established points were marked and the measurements were performed with the stereomicroscope (at × 150). The marginal fit of the samples were evaluated by calculating the mean measurements of each 16 points. The statistical analysis was performed by Tukey multiple comparisons test at 95% confidence interval. The groups can be summarized as follows in terms of marginal gap, from the lowest to highest: LAVA (24.6 ± 14.0 μm)相似文献   
8.
Dental restorations fail for a variety of reasons. Secondary caries is one of the primary causes of failure of dental restorations. One method for reducing frequency and severity of this problem is the use of fluoride containing restorative materials. The ability of a material to inhibit secondary caries formation is an important clinical therapeutic property. This investigation assessed the capacity of esthetic restorative materials to resist caries in vitro. Class V cavities were prepared in buccal and lingual surfaces of 50 extracted sound third molars. The occlusal and gingival cavosurface margin of each preparation was on enamel surface. The five materials were used: Conventional glass ionomer cement Ceramfil beta (PSP), two polyacid modified resin composites Compoglass (Vivadent) and Dyract (Dentsply/DeTrey), non fluoride releasing composite resin Valux Plus (3M) and fluoride releasing composite resin Tetric (Vivadent). After 10 weeks in an acid gel for caries-like lesion formation, the teeth were sectioned occluso-gingivally through the middle of the restorations and examined by polarized light microscopy, while immersed in water. The statistical analysis of the results showed that secondary caries initiation and progression might be reduced significantly when fluoride-containing materials were placed. The conventional glass ionomer cement (Ceramfil beta) provided the highest protection against caries attack and the non-fluoride releasing composite resin (Valux Plus) restoration provided the least (p<0.05).  相似文献   
9.
For patients with complex dentofacial problems, orthodontic treatment is often not enough to obtain optimal esthetic and functional results. This case report demonstrates the treatment of a patient with skeletal anteroposterior discrepancy through an interdisciplinary approach and emphasizes the importance of collaboration with other dental disciplines to achieve the desired esthetic results.  相似文献   
10.
AIMS: The aims of this study were to evaluate the effect of various finishing and polishing procedures on the surface roughness of six different composite resin materials (Artemis Enamel, TPH Spectrum, Filtek A-110, Filtek Supreme Enamel, Solitaire 2, and Filtek P-60) as well as to evaluate the effectiveness of the surface sealant application (BisCover) on the surface roughness after finishing and polishing procedures of tested composites. METHODS AND MATERIALS: Specimens (n=168) measuring 5 mm in diameter x 2 mm in thickness were fabricated in a plexiglass well covered with a Mylar strip using six composite resins. A control group of seven specimens of each material received no polishing after being cured under the Mylar strip. Twenty-one specimens for each composite were randomly divided among three finishing and polishing groups (n=7). Each group was polished using a different system: Carbide bur/Sof-Lex disc, Carbide bur/Enhance disc with polishing paste, and Carbide bur/Edenta composite finishing kit. The average surface roughness (Ra, microm) of the control and treated specimens were measured with the Mitutoyo Surftest-402 Surface Roughness tester. After a surface sealant (BisCover) was applied to all treated specimens, according to manufacturer's instructions, the average roughness (Ra) was measured again. Results were statistically analyzed using analysis of variance (ANOVA) and the post-hoc Scheffe's test at a p<0.05 significance level. RESULTS: Significant differences were found for the surface roughness (p<0.05) with interaction among composite resins and the finishing systems used (p<0.05). Enhance/Biscover finishing and polishing procedure surface was not significantly different from the Mylar strip surface groups (p>0.05). The Mylar strip group was not significantly different from the Sof-Lex/BisCover and Edenta/BisCover groups. The ranking of mean Ra values by materials was as follows: Filtek Supreme Enamel < Filtek A110 < TPH Spectrum < Artemis 相似文献   
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