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Nurse leaders at all levels, from ward to board to international stage, need to be savvy about politics, policy and power. They should be at the top table in every health‐related organization, and they should know how to make an impact in these challenging environments. Yet top nurses worldwide have few opportunities to develop their policy leadership competencies. The ICN Global Nursing Leadership Institute is a rare and successful example. For 10 years it has prepared top nurses from round the world to drive policy that improves population health, enhances health care, and advances the profession ‐ a major theme at ICN Congress, Singapore, June 2019. Jane Salvage, programme director, introduced GNLI at a packed session in the main hall, and two alumnae, Jed Montayre (New Zealand) and Michelle Gunn (Australia), described their transformational experiences of it. 相似文献
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A prospective evaluation of chronic Babesia microti infection in seroreactive blood donors 下载免费PDF全文
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Annette Estes Lonnie Zwaigenbaum Hongbin Gu Tanya St. John Sarah Paterson Jed T. Elison Heather Hazlett Kelly Botteron Stephen R. Dager Robert T. Schultz Penelope Kostopoulos Alan Evans Geraldine Dawson Jordana Eliason Shanna Alvarez Joseph Piven IBIS network 《Journal of Neurodevelopmental Disorders》2015,7(1)
Background
To delineate the early progression of autism spectrum disorder (ASD) symptoms, this study investigated developmental characteristics of infants at high familial risk for ASD (HR), and infants at low risk (LR).Methods
Participants included 210 HR and 98 LR infants across 4 sites with comparable behavioral data at age 6, 12, and 24 months assessed in the domains of cognitive development (Mullen Scales of Early Learning), adaptive skills (Vineland Adaptive Behavioral Scales), and early behavioral features of ASD (Autism Observation Scale for Infants). Participants evaluated according to the DSM-IV-TR criteria at 24 months and categorized as ASD-positive or ASD-negative were further stratified by empirically derived cutoff scores using the Autism Diagnostic Observation Schedule yielding four groups: HR-ASD-High, HR-ASD-Moderate (HR-ASD-Mod), HR-ASD-Negative (HR-Neg), and LR-ASD-Negative (LR-Neg).Results
The four groups demonstrated different developmental trajectories that became increasingly distinct from 6 to 24 months across all domains. At 6 months, the HR-ASD-High group demonstrated less advanced Gross Motor and Visual Reception skills compared with the LR-Neg group. By 12 months, the HR-ASD-High group demonstrated increased behavioral features of ASD and decreased cognitive and adaptive functioning compared to the HR-Neg and LR-Neg groups. By 24 months, both the HR-ASD-High and HR-ASD-Moderate groups demonstrated differences from the LR- and HR-Neg groups in all domains.Conclusions
These findings reveal atypical sensorimotor development at 6 months of age which is associated with ASD at 24 months in the most severely affected group of infants. Sensorimotor differences precede the unfolding of cognitive and adaptive deficits and behavioral features of autism across the 6- to 24-month interval. The less severely affected group demonstrates later symptom onset, in the second year of life, with initial differences in the social-communication domain.Electronic supplementary material
The online version of this article (doi:10.1186/s11689-015-9117-6) contains supplementary material, which is available to authorized users. 相似文献9.
Functional reorganization of language networks for semantics and syntax in chronic stroke: Evidence from MEG 下载免费PDF全文
Aneta Kielar Tiffany Deschamps Regina Jokel Jed A. Meltzer 《Human brain mapping》2016,37(8):2869-2893
Using magnetoencephalography, we investigated the potential of perilesional and contralesional activity to support language recovery in patients with poststroke aphasia. In healthy young controls, left‐lateralized ventral frontotemporal regions responded to semantic anomalies during sentence comprehension and bilateral dorsal frontoparietal regions responded to syntactic anomalies. Older adults showed more extensive bilateral responses to the syntactic anomalies and less lateralized responses to the semantic anomalies, with decreased activation in the left occipital and parietal regions for both semantic and syntactic anomalies. In aphasic participants, we observed compensatory recruitment in the right hemisphere (RH), which varied depending on the type of linguistic information that was processed. For semantic anomalies, aphasic patients activated some preserved left hemisphere regions adjacent to the lesion, as well as homologous parietal and temporal RH areas. Patients also recruited right inferior and dorsolateral frontal cortex that was not activated in the healthy participants. Responses for syntactic anomalies did not reach significance in patients. Correlation analyses indicated that recruitment of homologous temporoparietal RH areas is associated with better semantic performance, whereas higher accuracy on the syntactic task was related to bilateral superior temporoparietal and right frontal activity. The results suggest that better recovery of semantic processing is associated with a shift to ventral brain regions in the RH. In contrast, preservation of syntactic processing is mediated by dorsal areas, bilaterally, although recovery of syntactic processing tends to be poorer than semantic. Hum Brain Mapp 37:2869–2893, 2016. © 2016 Wiley Periodicals, Inc . 相似文献