Exercise training after coronary angioplasty improves cardiorespiratory function

Aim. The aim of this prospective randomized study was to evaluate the impact of long-term aerobic exercise training on respiratory function, left ventricular systolic function and remodeling in patients with coronary heart disease and ischemic heart failure after successful angioplasty. Design. Patients (n=185) have undergone Doppler echocardiography and ergospirometry. Ninety-five patients practiced 6 month-term aerobic exercise training, less by 10% to their anaerobic threshold. Ninety patients were studied as controls. They were given only drug treatment without training. Measurements were repeated after 6 and 12 months. Results. Training group patients after 6 months showed significant (p<0.05) improvement in exercise capacity, oxygen consumption and ventilating equivalents. The Doppler echocardiographic findings revealed significant (p<0.05) improvement in ejection fraction, left ventricular and atria morphometric data. Improved ergospirometric and echocardiographic data were established after 12 months, too. Conclusions. Long-term aerobic exercise training is an effective and workable measure improving respiratory efficiency, left ventricular systolic function, attenuating negative remodeling and stopping further progression in patients with coronary heart disease and chronic heart failure after successful angioplasty.     

Imbalance of Apoptosis and Cell Proliferation Contributes to the Development and Persistence of Emphysema

Background  

We postulate that in adults there is an established lung structure maintenance program and that lung alveolar septal cells are undergoing both continuous apoptosis and proliferation. Whereas lung cell apoptosis has been recognized in human emphysema, little is known about cell proliferation.     

Impact of a correct breathing stereotype on pulmonary minute ventilation, blood gases and acid-base balance in post-myocardial infarction patients.

STUDY OBJECTIVE: The aim of the study was to evaluate the impact of a long-term (6-month) correct breathing stereotype on minute ventilation, capillary blood gases and acid-base balance in post-myocardial infarction patients. METHODS: Fifty-five men (age 57.2 +/- 12.5) were examined 2 months later after myocardial infarction. Spirometry and assessment of acid-base balance and capillary blood gases were performed at rest and repeated after 10 days and 6 months. Breathing correction was taught over 5 days. A session for the control and maintenance of the correct breathing skills was hosted once a month (during the 6-month period). RESULTS: Changes of minute ventilation, capillary blood gases and acid-base balance were revealed in 55% of patients 2 months later after myocardial infarction. Twenty patients (group I) were randomly selected for breathing correction while 10 patients made up the control group (group II). After breathing correction minute ventilation significantly decreased (18.5 +/- 5.5 versus 9.8 +/- 2.5 l/min), oxygen ventilatory equivalent decreased (39.8 +/- 5.2 versus 22.5 +/- 3.8), partial pressure of blood carbon dioxide increased (33.2 +/- 1.7 versus 44.2 +/- 2.5 mmHg), plasma bicarbonate concentration augmented (19.1 +/- 2.2 versus 24.5 +/- 1.8 mmol/l), base excess normalized (-2.90 +/- 2.5 versus +1.3 +/- 2.1 mmol/l), and pH shifted to more alkaline value (7.36 +/- 0.01 versus 7.43 +/- 0.02). CONCLUSIONS: A long-term correct breathing stereotype improved respiratory function and could be an additional measure in rehabilitation programmes for post-myocardial infarction patients.     

Radiological assessment of children with pectus excavatum

Objective To assess what degree of chest wall deformation changes statistically reliably after surgery, using pre-and postoperative radiological examination data. Methods Radiological chest examinations were performed for 88 children before and after remedial operations. Pre-and postoperative chest radiograph and CT were performed to measure transversal chest width; sagittal left chest side depth, sagittal right chest side depth, sternovertebral distance, and vertebral body length. Derivative indices were also estimated: Vertebral index (VI), Frontosagittal index (FI), Haller index (HI) and asymmetry index. Computerized assessment of data was used. For statistical analysis, the software “Statistica 6.0” was used. Results Postoperatively VI increased approximately by 2.37±2.72, FI decreased by 4.60±4.34, and HI value increased approximately up by 0.45±0.49. Statistically significant deformation index difference before and after surgery was not detected when VI was below 26.2 (p=0.08), FI was above 32.9 (p=0.079) and HI was less than 3.12 (p=0.098). Conclusion Preoperative CT and X-ray assessment of chest wall deformation degree is important for pediatric patients. The following deformation indices are indications for surgical treatment: VI>26, FSI<33 and HI>3.1.     

Witzel catheter feeding jejunostomy: is it safe?

BACKGROUND/AIMS: Patients often suffer from malnutrition after digestive tract surgery. It leads to a longer recovery and a higher rate of postoperative complications. Early postoperative jejunostomy feeding is a way of tackling this problem. Opinions emerge that feeding via jejunostomy catheter is not the ideal method because of its complications. Our aim was to assess a complication rate of longitudinal Witzel catheter feeding jejunostomy and complications related to the onset of enteral feeding. METHODS: A retrospective analysis of case histories of 136 patients operated on for upper digestive tract diseases at our clinic between 1992 and 2004 with catheter feeding jejunostomy as an adjunct. We interviewed our patients by telephone about the jejunostomy-related complications during the 1st postoperative year. RESULTS: We observed two feeding jejunostomy-related complications (1.5%). Complications related to the onset of enteral feeding were observed in 12 cases (26.7%). There was no mortality. No complication of catheter jejunostomy was observed during the 1st postoperative year. CONCLUSIONS: A longitudinal Witzel catheter jejunostomy feeding is beneficial after surgery of the upper digestive tract. It is a rather safe procedure, which can be safely started on the day of operation.