Isoniazid resistance in patients with Extrapulmonary Tuberculosis using line probe assay in a private multispecialty hospital in Bangalore,India

We aimed to study the rate of isoniazid (INH) resistance in Extrapulmonary Tuberculosis samples from a private care setting.A Line probe assay was performed on 74 culture isolates of Mycobacterium tuberculosis or directly on extrapulmonary samples received in our laboratory from 2018 to 2021.The INH mono-resistance among these extrapulmonary samples was 6.7%. (5 among 74) (95% CI: 1.04%–12.48%) Resistance to rifampicin was not detected.Increasing the availability and leveraging public private partnerships in hospitals for universal testing for INH resistance may increase detection of INH monoresistance in EP-TB and improve the strategy for TB elimination.     

Are hospitals epicentres of COVID19 transmission? Findings of serial serosurveys among healthcare workers from a tertiary hospital in South India

We conducted a serial cross-sectional study and used blood bank donors serosurvey and the ICMR serosurvey reports for comparison. Seroprevalence was 0% among HCWs (n-211) and blood bank donors (n-210) during the first phase while ICMR serosurvey reported 0.5% among general population in the district at the same time. In phase 2, we estimated a seroprevalence of 9.2% as compared to 18.8% among general population. Seroprevalence among HCWs was comparable to that of the general population during both phases. We postulate that good infection control policies and practice can provide safe working environment without additional risk to HCWs.     

Satisfaction and genital perception after orchiectomy for prostate cancer: does the technique matter? A randomized trial

International Urology and Nephrology - Bilateral extracapsular or total orchiectomy (BEO) for prostate cancer is presumed to have psychological consequences after the surgery due to perception of...