排序方式: 共有7条查询结果,搜索用时 46 毫秒
1
1.
Arnold Danielle E. Chellapandian Deepak Parikh Suhag Mallhi Kanwaldeep Marsh Rebecca A. Heimall Jennifer R. Grossman Debra Chitty-Lopez Maria Murguia-Favela Luis Gennery Andrew R. Boulad Farid Arbuckle Erin Cowan Morton J. Dvorak Christopher C. Griffith Linda M. Haddad Elie Kohn Donald B. Notarangelo Luigi D. Pai Sung-Yun Puck Jennifer M. Pulsipher Michael A. Torgerson Troy Kang Elizabeth M. Malech Harry L. Leiding Jennifer W. 《Journal of clinical immunology》2022,42(5):1026-1035
Journal of Clinical Immunology - Granulocyte transfusions are sometimes used as adjunctive therapy for the treatment of infection in patients with chronic granulomatous disease (CGD). However,... 相似文献
2.
DeepakBabu Chellapandian Rupali Das Kristin Zelley Susan J. Wiener Huaqing Zhao David T. Teachey Kim E. Nichols EBV‐HLH Rituximab Study Group 《British journal of haematology》2013,162(3):376-382
Haemophagocytic lymphohistiocytosis (HLH) is a life threatening complication of Epstein–Barr virus (EBV) infection. The anti‐CD20 antibody rituximab depletes B cells, leading to improved outcomes for patients with EBV‐associated B‐lymphoproliferative disorders. To gather data on the use of rituximab in EBV‐HLH, we performed a retrospective investigation involving 42 EBV‐HLH patients who had received treatment with rituximab‐containing regimens. On average, patients received 3 rituximab infusions (range 1–10) at a median dose of 375 mg/m2. In all patients, rituximab was administered with other HLH‐directed medications, including steroids, etoposide and/or ciclosporin. Rituximab‐containing regimens appeared well tolerated and improved clinical status in 43% of patients. Examination of laboratory data obtained prior to and within 2–4 weeks after the first rituximab dose revealed significant reductions in EBV load (median load pre‐rituximab: 114 200 copies/ml, median post‐rituximab: 225 copies/ml, P = 0·0001) and serum ferritin levels (median ferritin pre‐rituximab: 4260 μg/l, median post‐rituximab: 1149 μg/l, P = 0·001). Thus, when combined with conventional HLH‐directed therapies, rituximab improves symptoms, reduces viral load and diminishes inflammation. These data support the incorporation of rituximab into future prospective clinical trials for patients with EBV‐HLH. 相似文献
3.
Arni?Raghavendrarao?RaghuramEmail author Subbaiyan?Kumar Kathamuthu?Balamurugan Venkatapathi?Sankarasubramanian Chellapandian?Suresh?Babu Ramiah?Krishnan 《Indian Journal of Thoracic and Cardiovascular Surgery》2005,21(3):234-235
Conclusion Rasmussen's aneurysm is a rare sequalae of pulmonary tuberculosis. The hemoptysis is usually massive and needs early and aggressive
management. Its management has been outlined and the available literature reviewed. 相似文献
4.
Management and Outcome of Patients With Langerhans Cell Histiocytosis and Single‐Bone CNS‐Risk Lesions: A Multi‐Institutional Retrospective Study 下载免费PDF全文
Deepak Chellapandian MD MBBS Furqan Shaikh MD Cor van den Bos MD PhD Gino R. Somers MBBS PhD Itziar Astigarraga MD PhD Rima Jubran MD Barbara Degar MD Anne‐Sophie Carret MD Karen Mandel MD Mark Belletrutti MD David Dix MD Johannes Visser MD Nour Abuhadra MD Tiffany Chang MD Barret Rollins MD PhD James Whitlock MD Sheila Weitzman MB Oussama Abla MD 《Pediatric blood & cancer》2015,62(12):2162-2166
5.
Myeloid neoplasms in children with sickle cell disease have been rarely reported, and the exact underlying connection between these two conditions is not clearly understood. Whether the acute myeloid leukemia in hydroxyurea‐treated sickle cell patients is co‐incidental or related to therapy remains an unanswered question. Herein, we report a 14‐year‐old girl of Haitian descent with sickle beta zero thalassemia on chronic hydroxyurea therapy who developed FMS‐like tyrosine kinase 3 (FLT3)‐mutated acute myeloid leukemia and underwent a complete disease remission following a combination chemotherapy with sorafenib and was subsequently treated using a T cell replete unmanipulated haploidentical bone marrow transplantation followed by post‐transplant cyclophosphamide. 相似文献
6.
Successful Allogeneic Hematopoietic Stem Cell Transplantation in XIAP Deficiency Using Reduced‐Intensity Conditioning 下载免费PDF全文
7.
Deepak Chellapandian MD MBBS Melissa R. Hines MD Rui Zhang MD Michael Jeng MD Cor van den Bos MD Vicente Santa-María López MD Kai Lehmberg MD Elena Sieni MD Yini Wang MD Taizo Nakano MD James A. Williams MD Nicholas J. Fustino MD Itziar Astigarraga MD Ira J. Dunkel MD Oussama Abla MD Astrid G.S. van Halteren MD Deqing Pei MS Cheng Cheng PhD Sheila Weitzman MD Lillian Sung MD Kim E. Nichols MD 《Cancer》2019,125(6):963-971
1