全文获取类型
收费全文 | 122篇 |
免费 | 9篇 |
专业分类
耳鼻咽喉 | 2篇 |
儿科学 | 11篇 |
妇产科学 | 5篇 |
基础医学 | 9篇 |
口腔科学 | 1篇 |
临床医学 | 4篇 |
内科学 | 20篇 |
皮肤病学 | 1篇 |
神经病学 | 29篇 |
特种医学 | 3篇 |
外科学 | 18篇 |
预防医学 | 5篇 |
药学 | 11篇 |
肿瘤学 | 12篇 |
出版年
2022年 | 4篇 |
2021年 | 14篇 |
2020年 | 2篇 |
2019年 | 8篇 |
2018年 | 17篇 |
2017年 | 8篇 |
2016年 | 2篇 |
2015年 | 8篇 |
2014年 | 7篇 |
2013年 | 10篇 |
2012年 | 6篇 |
2011年 | 9篇 |
2010年 | 5篇 |
2009年 | 5篇 |
2008年 | 5篇 |
2007年 | 4篇 |
2006年 | 1篇 |
2005年 | 5篇 |
2004年 | 3篇 |
2003年 | 1篇 |
2002年 | 1篇 |
2001年 | 1篇 |
1995年 | 1篇 |
1993年 | 1篇 |
1988年 | 1篇 |
1979年 | 1篇 |
1969年 | 1篇 |
排序方式: 共有131条查询结果,搜索用时 22 毫秒
1.
Stephanie H. Ameis John D. Haltigan Rachael E. Lyon Amanda Sawyer Pat Mirenda Connor M. Kerns Isabel M. Smith Tracy Vaillancourt Joanne Volden Charlotte Waddell Lonnie Zwaigenbaum Teresa Bennett Eric Duku Mayada Elsabbagh Stelios Georgiades Wendy J. Ungar Anat Zaidman-Zait Meng-Chuan Lai Peter Szatmari for the Pathways in ASD Study Team 《Journal of child psychology and psychiatry, and allied disciplines》2022,63(5):553-562
2.
Hawwam Soha Abdalla Ismail Mayada El-Attar Yasmina Ahmed 《Lasers in medical science》2022,37(4):2193-2201
Lasers in Medical Science - Melasma is a chronic, dark brown–pigmented patches and macules commonly on the face. Many treatment modalities for melasma have been used as hydroquinone, laser... 相似文献
3.
Mayada Elsabbagh Rachael Bedford Atsushi Senju Tony Charman Andrew Pickles Mark H. Johnson The BASIS Team 《Social cognitive and affective neuroscience》2014,9(4):538-543
Infants’ visual scanning of social scenes is influenced by both exogenously and endogenously driven shifts of attention. We manipulate these factors by contrasting individual infants’ distribution of visual attention to the eyes relative to the mouth when viewing complex dynamic scenes with multiple communicative signals (e.g. peek-a-boo), relative to the same infant viewing simpler scenes where only single features move (moving eyes, mouth and hands). We explore the relationship between context-dependent scanning patterns and later social and communication outcomes in two groups of infants, with and without familial risk for autism. Our findings suggest that in complex scenes requiring more endogenous control of attention, increased scanning of the mouth region relative to the eyes at 7 months is associated with superior expressive language (EL) at 36 months. This relationship holds even after controlling for outcome group. In contrast, in simple scenes where only the mouth is moving, those infants, irrespective of their group membership, who direct their attention to the repetitive moving feature, i.e. the mouth, have poorer EL at 36 months. Taken together, our findings suggest that scanning of complex social scenes does not begin as strikingly different in those infants later diagnosed with autism. 相似文献
4.
5.
Jonathan Green Ming Wai Wan Jeanne Guiraud Samina Holsgrove Janet McNally Vicky Slonims Mayada Elsabbagh Tony Charman Andrew Pickles Mark Johnson 《Journal of autism and developmental disorders》2013,43(11):2502-2514
Theory and evidence suggest the potential value of prodromal intervention for infants at risk of developing autism. We report an initial case series (n = 8) of a parent-mediated, video-aided and interaction-focused intervention with infant siblings of autistic probands, beginning at 8–10 months of age. We outline the theory and evidence base behind this model and present data on feasibility, acceptability and measures ranging from parent-infant social interaction, to infant atypical behaviors, attention and cognition. The intervention proves to be both feasible and acceptable to families. Measurement across domains was successful and on larger samples promise to be an effective test of whether such an intervention in infancy will modify emergent atypical developmental trajectories in infants at risk for autism. 相似文献
6.
Sally M. Clifford Kristelle Hudry Mayada Elsabbagh Tony Charman Mark H. Johnson 《Journal of autism and developmental disorders》2013,43(3):673-686
The current study investigated early temperament in 54 infants at familial high-risk of ASD and 50 controls. Parental report of temperament was assessed around 7, 14 and 24 months of age and diagnostic assessment was conducted at 3 years. The high-risk group showed reduced Surgency at 7 and 14 months and reduced Effortful Control at 14 and 24 months, compared to controls. High-risk infants later diagnosed with ASD were distinguished from controls by a temperament profile marked by increased Perceptual Sensitivity from the first year of life, and increased Negative Affect and reduced Cuddliness in the second year of life. Temperament may be an important construct for understanding the early infant development of ASD. 相似文献
7.
Woo So-Yeun Wong Chin Piow Win Nwet Nwet Lae Khine Zar Wynn Woo Bokyoung Elsabbagh Sherif Adel Liu Qian Qian Ngwe Hla Morita Hiroyuki 《Journal of natural medicines》2019,73(4):805-813
Journal of Natural Medicines - Jatropha multifida is a medicinal plant that belongs to the Euphorbiaceae family. Our investigation revealed that the chloroform extract of J. multifida stems showed... 相似文献
8.
Tanveer Sharif Cyril Auger Mahmoud Alhosin Claudine Ebel Mayada Achour Nelly Étienne-Selloum Guy Fuhrmann Christian Bronner Valérie B. Schini-Kerth 《European journal of cancer (Oxford, England : 1990)》2010,46(5):983-994
Several epidemiological studies suggest that a diet rich in fruits and vegetables, which contain high levels of polyphenols, is associated with a reduced risk of cancer. The aim of the present study was to determine whether a red wine polyphenolic extract (RWPs, a rich source of polyphenols; 2.9 g/L) affects the proliferation of human lymphoblastic leukaemia cells (Jurkat cells) and, if so, to determine the underlying mechanism. Cell proliferation and viability were determined by the MTS and trypan blue exclusion assays, respectively. Cell cycle analysis, apoptosis activity and oxidative stress levels were assessed by flow cytometry, and the expression of p73, UHRF1 and active caspase-3 by Western blot analysis. RWPs inhibited the proliferation of Jurkat cells and induced G0/G1 cell cycle arrest in a concentration-dependent manner. Moreover, RWPs triggered apoptosis, which is associated with an increased expression level of the pro-apoptotic protein p73 and the active caspase-3. RWPs induced apoptosis confirmed by DNA fragmentation analysis, and this effect was associated with down-regulation of the antiapoptotic protein UHRF1. Furthermore RWPs significantly increased the formation of reactive oxygen species (ROS). Intracellular scavengers of superoxide anions (MnTMPyP, MnTBAP, PEG-SOD) prevented the RWPs-induced formation of ROS and apoptosis, while native extracellular superoxide dismutase (SOD) was without effect. In addition, the effect of RWPs on the expression levels of p73, active caspase-3 and UHRF1 was also prevented by MnTMPyP. Thus, these findings indicate that RWPs induce apoptosis in Jurkat cells by a redox-sensitive mechanism involving the intracellular formation of superoxide anions and consequently the up-regulation of p73 and down-regulation of UHRF1. 相似文献
9.
10.
Anat Zaidman-Zait Pat Mirenda Peter Szatmari Eric Duku Isabel M. Smith Tracy Vaillancourt Joanne Volden Charlotte Waddell Teresa Bennett Lonnie Zwaigenbaum Mayada Elsabaggh Stelios Georgiades Wendy J. Ungar The Pathways in ASD Study Team 《Journal of autism and developmental disorders》2018,48(6):2077-2077