跖跗关节骨折脱位诊治体会

随着交通、工伤事故增多，跖跗关节（Lisfrane关节）损伤明显增多。由于跖跗关节为中足一复杂的复合性结构，处于足弓顶部，在步态中支撑体重，它的损伤、破坏常严重影响步行或致足畸形，此类损伤在临床中并不少见，易漏诊，因其结构复杂，在诊治中易出现失误。我院2001年6月～2005年6月共收治跖跗关节骨折脱位12例，现分析总结如下。     

肝硬化腹水并原发性腹膜炎88例临床分析

肝硬化腹水并发原发性腹膜炎(SBP)是肝硬化晚期严重并发症和主要死亡原因之一。因早期症状不典型而易误诊。本文对我们1982～1990年间收治的88例作一总结,并对早期诊断及预防作一讨论。     

精神分裂症病人康复期的家庭治疗与护理

精神分裂症的复发是精神科临床常常面临的棘手问题.该病由于反复发病或迁延不愈常残留慢性症状或人格障碍.要使病人最大限度地康复,待出院后尚需要长时间的继续服药.一般来讲,初次治愈者继续服药时间不能少于5年,多次治愈者应终生服药,以巩固其治疗效果及预防复发.精神症状基本稳定的康复期病人有较强的康复出院回归社会的愿望,在这段期间,病人往往不愿意服药,而如果停药或受到精神刺激则极易导致病情复发.     

HER-2/neu基因表达对Ⅲ期非小细胞肺癌化疗敏感性的影响

【目的】探讨HER 2 /neu基因表达对Ⅲ期NSCLC化疗敏感性的影响。【方法】对 2 2例中晚期NSCLC患者术前化疗后行手术治疗 ,标本采用免疫组化法进行HER 2 /neu检测 ,分析HER 2 /neu与化疗显效率、疾病进展时间 (TTP)的关系。【结果】 2 2例患者围手术期无 1例死亡。HER 2 /neu( ) 9例 ,HER 2 /neu( -) 13例。HER 2 /neu( )组中化疗有效率为 44 4% ,HER 2 /neu( -)组则为 30 7%。经 χ2 检验P值 0 416 ;HER 2 /neu( )组与阴性组其TTP亦无显著性差异 (P为 0 5 11)。【结论】HER 2 /neu可能不是独立的化疗敏感性的预测因子 ,仍需开展进一步实验。     

人工全髋关节置换术围手术期的康复和护理

随着老龄人口的增加,人工全髋关节置换术的病例数逐年上升.成功的手术、围手术期良好的康复以及护理是获得良好的术后效果的关键.本文对全髋关节置换术的基本知识、围手术期的康复以及护理方法进行了综述.     

Iq7611放射增敏治疗食管癌的效果观察

Iq7611是天津市医药科学研究所研制的醌类成份放射增敏药物。初步实验室研究表明可降低细胞氧耗量,增加氧分压,又可降低癌细胞谷胱甘肽的含量,使癌细胞丧失或减少了对射线的防护能力。自1982年2月到1984年12月,在我院临床应用。进行了62     

传统草药("汉方药")与药物性肝损害

一、何谓“汉方药”？ “汉方药”（漠方蕖）是由数种生药组合而成，各药分量是遵古方所载，业已沿用数百乃至两千余年的传统方剂。某些煎剂（依现代技术制成）现亦列入日本医保范畴。     

PET/CT在评价及观察大鼠肺癌放疗效果中的应用

Objective The aim of this study was to understand the role of PET/CT in monitoring the therapeutic effect of radiotherapy (RT) on lung cancer with Wistar rats. Methods Thirty Wistar in-bred strain rats (6-8 weeks, weighed 180-280 g, female, ordinary) were made into Lewis pulmonary tumor model rats. 18F-fluorodeoxyglucose (FDG) PET/CT was performed when tumor reached 1.5-2.0 cm in greatest diameter (4-6 weeks) as a baseline. In order to get the optimal time point of PET/CT for moni-toring RT effect in rat cancer model, PET/CT was performed at the 3rd day, 1st, 2nd, 3rd, and 4th week after giving single dose of 5 Gy to each rat. Standardized uptake values (SUV) from FDG PET were measured and rats were sacrificed at different time point for validation. Besides, the expressions of glucose transport1 (Glut1) in tumor tissue were studied using immunohistochemistry. The level of tumor cell apoptosis, degra-dation, and necrosis were observed. SPSS 11.0 software was used for data analyses. Results A negative correlation of SUV uptake and time after RT and negative correlation of Glut1 expression and time after RT were observed in rat tumors, respectively. Positive correlation of SUV uptake and Glut1 expression in rat tumors was observed (Spearman rank correlation test, rs = 0.97, P < 0.01). Before RT, the SUV in rat tumor was 1.28 ± 0.31 and was decrease to 1. 00 ± 0.23 at the 3rd day and 0.18 ± 0. 10 at the 4th week after RT (F=15. 126, P<0.05). Before RT, the Glut1 in rat tumor was 0.2558 ±0.03 and was decrease to 0. 2320 ± 0. 01 at the 3rd day and 0. 1320±0.04 at the 4th week after RT. The amounts of tumor cell apopto-sis, degradation, and necrosis increased with time after RT. Conclusion Though FDG PET could monitor the therapeutic effect at the 3rd day after giving single dose of RT to rat lung tumor model, the optimal time was the the 4th week after treatment.