芪芍护脑荣筋胶囊治疗中风后痉挛性瘫痪临床研究

目的 观察芪芍护脑荣筋胶囊对中风后痉挛性瘫痪的疗效。方法 162例患者随机分为治疗组100例和对照组62例。治疗组以芪芍护脑荣筋胶囊配合内科常规治疗及针灸、康复治疗；对照组以内科常规治疗配合针灸、康复治疗。3月后两组进行神经功能缺损程度（NIHSS）评定、改良Ashworth痉挛量表评级（Modified Ashworth Scale，MAS）、中医证候积分比较及不良反应观察。结果 2组NIHSS评定经统计学处理有显著性差异．P〈0．01；治疗组临床痊愈20例，显效56例，有效21例，无效3例，总有效率97％，显效率76％。对照组临床痊愈4例，显效20例，有效34例，无效4例，总有效率93．55％，显效率38．71%。2组显效率经统计学处理有显著性差异P〈0．01；2组MAS评级治疗组优于对照组；中医证候积分变化比较亦有显著性差异，P〈0．05。未发现与使用药物相关的不良反应。结论 芪芍护脑荣筋胶囊治疗中风后痉挛性瘫痪具有良好的疗效。     

背腧穴为主点穴按摩治疗脑中风偏瘫的临床护理研究

目的：观察以背腧穴为主点穴按摩治疗脑中风偏瘫的临床护理疗效。方法：120例患者随机分为治疗组72例和对照组48例，治疗后进行临床疗效评定及改良Ashworth评级变化比较。结果：治疗组总有效率97．22％，愈显率72．22％。对照组总有效率91．67％，愈显率39．58％。两组疗效经统计学处理差异有显著性（P〈0．01）。两组改良Ashworth评级治疗后对比，也有显著性差异（P〈0．01）。结论：背腧穴为主点穴按摩这一护理特色项目，与常规治疗结合治疗脑中风可使疗程缩短，疗效提高。     

牵引联合温热式低周波治疗腰椎间盘突出症临床观察

目的观察电脑控制间歇牵引联合温热式低周波治疗腰椎间盘突出症的临床疗效。方法将200例患者随机分为治疗组和对照组各100例,治疗组给予电脑控制间歇牵引合温热式低周波治疗,对照组单纯给予电脑控制间歇牵引治疗。每日1次,12次为1个疗程,治疗2个疗程后统计疗效。结果治疗组治愈81例,好转17例,总有效率98％;对照组治愈43例,好转42例,总有效率85％。治疗组治愈率及总有效率均明显高于对照组（P〈0．05）。结论温热式低周波治疗与电脑控制间歇牵引具有协同作用,可明显提高牵引治疗腰椎间盘突出症的临床疗效。     

温针灸治疗肩关节周围炎随机对照临床研究文献Meta分析

目的：系统评价温针灸治疗肩关节周围炎的疗效。方法：对1998年1月-2012年12月中国期刊全文数据库（CNKI）、万方数据库中相关文献进行电子检索,纳入温针灸治疗肩周炎与其他疗法比较的随机对照试验（RCT）和临床对照试验（CCT）根据Jadad评分标准评价纳入研究项目的质量。使用RevMan5.1版进行Meta分析统计学处理。结果：9篇文献符合纳入标准,共计1076例患者。Meta分析结果显示温针灸能显著治疗肩关节周围炎,温针灸治疗组总优势比OR=7.59,95%置信区间（CI）为（4.35-13.27）。两者差异有统计学意义（P〈0.00001）;＂漏斗图＂图形显示存在发表偏倚。结论：资料表明温针灸治疗肩关节周围炎临床疗效显著。尤其在改善症状及整体疗效方面,但还需要高量的随机对照试验进一步验证支持。     

中医药高校学报特色栏目数字化建设

在融合发展及中医药发展战略的背景下,中医药高校学报紧跟媒体融合的趋势,发挥数字媒体的优势,将传统纸质媒介与数字媒体结合,共同打造特色栏目。分析了《陕西中医药大学学报》“岐黄新语”“三秦医药”“疫病防治”3个特色栏目的数字化建设情况,并从特色栏目选题策划、特色栏目数字化建设发展思路和路径、特色栏目数字化建设效果反馈等方面总结了其特色栏目数字化建设经验,为发扬、传承、挖掘中医药知识做出贡献。     

Experimentally investigating the effect of buccal acupuncture on analgesic time-effect characteristics and monoamine neurotransmitters

Objective

To investigate the analgesic time-effect characteristics and changes in concentrations of rabbit’s hypothalamic 5-hydroxytryptamine (5-HT) and noradrenaline (NE) caused by buccal acupuncture in the rheumatoid arthritis (RA) rabbits, and to reveal the analgesic central mechanism of buccal acupuncture, thereby providing a theoretical basis for the treatment of pain by buccal acupuncture.

Methods

Forty rabbits were randomly divided into a normal group, a model group, a body acupuncture group, and a buccal acupuncture group, with 10 rabbits in each group. No model was established in the normal group, while equal dose of normal saline was injected at the matched site and time point; rabbits in other groups were subjected to the establishment of RA models using egg protein. From the 27th day of the experiment, rabbits in each group received the designated intervention. Rabbits in the normal group and the model group were fixed for 30 min every day using the same method as those in the other groups. In the acupuncture group, Dubi (ST 35) and Zusanli (ST 36) on bilateral hind limbs were selected. Perpendicular needling (using the needles with 0.25 mm in diameter and 25 mm in length) was performed with twirling manipulation for 15 s at intervals of 5 min. The needles were retained for 30 min and acupuncture was performed once a day. In the buccal acupuncture group, the knee point in the buccal acupuncture and needles with a diameter of 0.25 mm and a length of 15 mm were selected. Oblique needling was performed with twirling manipulation for 15 s at intervals of 5 min. The needles were retained for 30 min and acupuncture was performed once a day. The thermal pain thresholds at the 0, 5, 15, 30, 60, 120 and 240 min after the 1st and 10th acupuncture therapy were measured with a PL-200 thermal-inducing pain meter. After the 10th acupuncture therapy, rabbit’s hypothalamus was removed, and the 5-HT and NE concentrations in the hypothalamus at the peak point of the acupuncture pain threshold curve were determined by high performance liquid chromatography (HPLC).

Results

The analgesic effect was obvious at 5 min after buccal acupuncture started, peaked at 30 min, and decreased to the lowest value at 240 min. Rabbits in the body acupuncture group began to show significant analgesic effect at 15 min, which was peaked at 30 min, and began to decline at 60 min. The pain threshold at 240 min was still higher than that at 0 min. Compared with the model group, the concentrations of hypothalamic 5-HT in the buccal acupuncture group and the body acupuncture group was significantly increased, and the between-group differences were statistically significant (both P<0.05). The NE/5-HT ratios in hypothalamus in the buccal acupuncture group and the body acupuncture group were significantly lower than the ratio in the model group, and the differences were statistically significant (both P<0.05); difference in the decrease was statistically significant between the buccal acupuncture group and the body acupuncture group (P<0.05).

Conclusion

The analgesic effect of buccal acupuncture shows an obvious time-dependent curve. It is characterized by rapid onset of pain relief, rapid increase and decline in pain threshold. 5-HT and NE levels in rabbit’s hypothalamus can be affected by buccal acupuncture, with increased 5-HT concentration and reduced NE/5-HT ratio.

     

超声电导仪“冬病夏治”治疗哮喘30例疗效观察

目的:观察超声电导仪“冬病夏治”的治疗效果。方法:将60例患者依就诊顺序随机分为治疗组(30例)和对照组(30例),治疗组采用超声电导穴位经皮给药治疗,对照组采用传统天灸治疗。结果:治疗组痊愈率10%,总有效率96.7%;对照组痊愈率0%,总有效率83.3%。结论:超声电导仪治疗哮喘疗效确切。     

近6年针灸治疗阿尔茨海默病临床研究述评与展望

目的评述针灸治疗阿尔茨海默病的临床研究现状。方法检索中国知网数据库、维普中文科技期刊数据库、PubMed英文数据库。检索时间从2015年1月至2020年12月。纳入文献提取的数据信息主要包括文献的发表数量、诊断标准、治疗方法与结果、腧穴选择与操作手法、治疗时间与疗程、及目前存在的问题等。结果针灸治疗阿尔茨海默病的文献自2015年以来呈逐年增多的趋势,诊断标准和疗效标准的使用缺乏统一和规范。治疗方法主要有两类,一类为针灸疗法配合药物治疗,一类为各种针灸疗法的单独或组合运用。单独作为干预措施使用的针灸疗法以体针、头针和电针居多。使用频率较高的腧穴依次为百会、神庭、四神聪、玉枕、风府等。结局指标以有效率为最多。结论目前不论何种针灸治疗方法对阿尔茨海默病患者都有一定的治疗效果。与此同时,如何优化腧穴配伍、针刺手法、治疗过程中把控质量控制,从而获得最佳疗效,都将是以后临床研究的重点。     

超声电导透皮给药佐治小儿肺炎疗效观察

目的 通过运用中药贴片经皮超声电导给药观察和分析该疗法的治疗效果，从而提高小儿肺炎的治愈率。方法 在常规治疗的基础上，运用电超导治疗仪将中药贴片贴在双侧肩胛下区（肺俞穴处），将配对治疗头固定在凝胶贴片背面，进行透皮治疗15min，结束后撤去治疗头，保留贴片2～4h，每天1次，4次为1个疗程。结果 治疗组32例，治愈16例，有效15例，无效1例，总有效率为97％。对照组20例，4天后总有效率70％，两组比较差异有显著性（X^2=6．1，P〈0．05）。结论 在综合治疗基础上，加用中药贴片佐治小儿肺炎，疗程短、有效率高、副作用小，值得推广使用。     

微针系统针刺镇痛研究文献计量学分析

目的：反映近10年来微针镇痛的现状及发展趋势。方法运用文献计量学方法,检索中国期刊全文数据库微针镇痛的相关文献,并对其进行文献计量学分析,从文献的年份分布、各种微针疗法文献分布、文献类型等方面进行统计,初步研究与分析本领域的科研现状。结果共纳入文献590篇,微针镇痛研究文献数量趋势呈缓慢上升状态;各种不同的微针疗法文献数量相差悬殊;文献主要集中在临床研究上,机理研究文献数量很少。结论微针镇痛研究正逐渐得到认同和重视。但需进一步加强机理研究,为临床提供理论指导,使微针系统疗法得到进一步推广和应用。