全文获取类型
收费全文 | 24705篇 |
免费 | 1262篇 |
国内免费 | 149篇 |
专业分类
耳鼻咽喉 | 356篇 |
儿科学 | 396篇 |
妇产科学 | 493篇 |
基础医学 | 3158篇 |
口腔科学 | 622篇 |
临床医学 | 1834篇 |
内科学 | 6825篇 |
皮肤病学 | 274篇 |
神经病学 | 1844篇 |
特种医学 | 710篇 |
外科学 | 4224篇 |
综合类 | 99篇 |
一般理论 | 1篇 |
预防医学 | 729篇 |
眼科学 | 370篇 |
药学 | 1673篇 |
中国医学 | 42篇 |
肿瘤学 | 2466篇 |
出版年
2023年 | 140篇 |
2022年 | 147篇 |
2021年 | 549篇 |
2020年 | 299篇 |
2019年 | 342篇 |
2018年 | 495篇 |
2017年 | 352篇 |
2016年 | 437篇 |
2015年 | 422篇 |
2014年 | 589篇 |
2013年 | 741篇 |
2012年 | 1103篇 |
2011年 | 1171篇 |
2010年 | 642篇 |
2009年 | 559篇 |
2008年 | 1115篇 |
2007年 | 1166篇 |
2006年 | 1083篇 |
2005年 | 1026篇 |
2004年 | 1006篇 |
2003年 | 998篇 |
2002年 | 1013篇 |
2001年 | 892篇 |
2000年 | 930篇 |
1999年 | 804篇 |
1998年 | 293篇 |
1997年 | 216篇 |
1996年 | 200篇 |
1995年 | 185篇 |
1994年 | 161篇 |
1993年 | 144篇 |
1992年 | 599篇 |
1991年 | 626篇 |
1990年 | 533篇 |
1989年 | 540篇 |
1988年 | 522篇 |
1987年 | 497篇 |
1986年 | 427篇 |
1985年 | 429篇 |
1984年 | 313篇 |
1983年 | 238篇 |
1979年 | 231篇 |
1978年 | 133篇 |
1977年 | 139篇 |
1974年 | 128篇 |
1973年 | 120篇 |
1972年 | 137篇 |
1971年 | 127篇 |
1969年 | 138篇 |
1967年 | 128篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Hori Hiroki Ohta Asuka Matsui Honami Yano Kanako Morita-Tominaka Miyuki Linn Zayar Masumoto Daisuke Okumura Yosuke Okamura Satoshi Kurihara Kosuke Hayakawa Akira Rikiishi Takeshi Kobayashi Kyoko 《International journal of clinical oncology / Japan Society of Clinical Oncology》2022,27(1):245-252
International Journal of Clinical Oncology - The practice of cancer diagnosis disclosure to children has been changed with the times. The regulations of clinical trials in the 2000s might change... 相似文献
2.
3.
Kensuke Kudou Hiroshi Saeki Yuichiro Nakashima Shun Sasaki Tomoko Jogo Kosuke Hirose Qingjiang Hu Yasuo Tsuda Koichi Kimura Ryota Nakanishi Nobuhide Kubo Koji Ando Eiji Oki Tetsuo Ikeda Yoshihiko Maehara 《American journal of surgery》2019,217(4):757-763
Background
There were few studies assessed the postoperative sarcopenia in patients with cancers. The objective of present study was to assess whether postoperative development of sarcopenia could predict a poor prognosis in patients with adenocarcinoma of esophagogastric junction, (AEG) and upper gastric cancer (UGC).Methods
Patients with AEG and UGC who were judged as non-sarcopenic before surgery were reassessed the presence of postoperative development of sarcopenia 6 months after surgery. Patients were divided into the development group or non-development group, and clinicopathological factors and prognosis between these two groups were analyzed.Results
The 5-year overall survival rates were significantly poorer in the development group than non-development group (68.0% vs. 92.6%, P?=?0.0118). Multivariate analyses showed that postoperative development of sarcopenia was an independent prognostic factor for poor overall survival (P?=?0.0237).Conclusions
Postoperative development of sarcopenia was associated with a poor prognosis in patients with AEG and UGC. 相似文献4.
5.
6.
7.
8.
Koji Saito Takashi Saito Sumio Kawada 《Nihon Shokakibyo Gakkai zasshi》2006,103(10):1176, 1179-1176, 1180
9.
Masahiro Yamauchi Hiroko Kusano Etsuko Saito Takeshi Iwata Masashi Nakakura Yasuki Kato Takaaki Uochi Shiro Akinaga Noboru Aoki 《Journal of controlled release》2006,114(2):268-275
Previously, we demonstrated that wrapping dextran fluorescein anionic/cationic lipid complexes with neutral lipids produced a stable formulation that markedly increased the duration of the compound in plasma after intravenous administration to rats. The improved drug-delivery properties of the wrapped liposomes (WL) relative to other formulations suggested that this technology could offer important advantages for the administration of other polyanionic drugs, including antisense oligodeoxynucleotides (ODN). In the present study, we investigated the value of WL for formulating fluorescence-labeled phosphorothioated ODN (F-ODN). WL encapsulating F-ODN/cationic lipid complexes were prepared efficiently using similar methodology to that used in our earlier study. Studies confirmed that these WL were stable in vitro. Following intravenous administration to mice, free F-ODN and naked F-ODN/cationic lipid complexes were rapidly eliminated whereas administration of the WL resulted in high blood concentrations of drug that were maintained for several hours. Additional studies were conducted in mice that were inoculated with tumor cells (Caki-1 xenograft model, human kidney); in these experiments, intravenous administration of WL delivered 13 times more F-ODN to the tumor site than achieved after injection of free F-ODN. 相似文献
10.
Kosuke Kaida Masaya Takahashi Torbj?rn Akerstedt Akinori Nakata Yasumasa Otsuka Takashi Haratani Kenji Fukasawa 《Clinical neurophysiology》2006,117(7):1574-1581
OBJECTIVE: The Karolinska sleepiness scale (KSS) is frequently used for evaluating subjective sleepiness. The main aim of the present study was to investigate the validity and reliability of the KSS with electroencephalographic, behavioral and other subjective indicators of sleepiness. METHODS: Participants were 16 healthy females aged 33-43 (38.1+/-2.68) years. The experiment involved 8 measurement sessions per day for 3 consecutive days. Each session contained the psychomotor vigilance task (PVT), the Karolinska drowsiness test (KDT-EEG alpha & theta power), the alpha attenuation test (AAT-alpha power ratio open/closed eyes) and the KSS. RESULTS: Median reaction time, number of lapses, alpha and theta power density and the alpha attenuation coefficients (AAC) showed highly significant increase with increasing KSS. The same variables were also significantly correlated with KSS, with a mean value for lapses (r=0.56). CONCLUSIONS: The KSS was closely related to EEG and behavioral variables, indicating a high validity in measuring sleepiness. SIGNIFICANCE: KSS ratings may be a useful proxy for EEG or behavioral indicators of sleepiness. 相似文献