铜绿假单胞菌注射液联合多西他赛和顺铂治疗肺癌所致恶性胸腔积液疗效观察

目的观察铜绿假单胞菌注射液联合DP方案（多西他赛＋顺铂）化疗治疗非小细胞肺癌所致恶性胸腔积液的效果及安全性。方法非小细胞肺癌并恶性胸腔积液患者66例,随机分为观察组37例和对照组29例,2组均应用DP方案化疗2个周期。注射化疗药物7d后经B超证实胸腔积液排净或胸腔积液引流量〈50mL／d时,观察组经胸腔灌注铜绿假单胞菌注射液,对照组经胸腔灌注白细胞介素-2。胸腔灌注治疗结束后6周评价2组疗效并观察不良反应发生情况。结果观察组有效率（89．2％）高于对照组（69．0％）（P〈0．05）;观察组发热及胸痛发生率分别为43．2％和48．6％,对照组分别为为24．1％和27．6％,2组比较差异无统计学意义（P〉0．05）。结论铜绿假单胞菌注射液胸腔灌注联合DP方案治疗非小细胞肺癌恶性胸腔积液疗效满意,不良反应轻。     

贝朗Dialog＋血液透析机故障维修2例

由于血液透析机内部电路和水路复杂,且长期在酸、碱性液体环境中运行,导致机器内部的电路和水路遭到很强的腐蚀,较为多见的是水路故障。现就我中心贝朗Dialog＋型透析机出现的2例水路报警故障进行详细论述。     

调督安神针法治疗失眠症疗效观察（英文）

目的:观察调督安神针法对失眠症的疗效,传承燕赵高氏针灸学术思想。方法:将68例失眠症患者按随机数字表随机分为针刺组及药物组,每组34例。针刺组采用调督安神针法治疗,每日1次,每星期治疗5次,休息2d,共治疗4星期。药物组予艾司唑仑片治疗,每日1mg,睡前口服,共治疗4星期。治疗前后采用匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)评价睡眠质量,根据P SQI减分率评定疗效。结果:治疗后,针刺组PSQI总分及各单项评分均明显下降,与本组治疗前有统计学差异(均P<0.01);药物组P SQI总分明显下降,与本组治疗前差异有统计学意义(均P<0.01),除睡眠障碍外,其余各单项积分均较治疗前下降(P<0.01或P<0.05)。针刺组治疗后P SQI总分明显低于药物组(P<0.01)。除入睡时间及睡眠时间外,针刺组睡眠质量、睡眠效率、睡眠障碍及日间功能障碍评分均低于药物组,组间差异有统计学意义(均P<0.05)。针刺组愈显率显著高于药物组(P<0.05)。结论:调督安神针法治疗失眠疗效确切,疗效优于口服艾司唑仑片。     

哲学视野中艺术的价值

哲学本质上是人学,哲学视野中艺术的价值应与人的生命紧密相连。艺术价值贯穿于古今中外的艺术理论发展中,是艺术哲学中的一个重要课题。艺术价值在哲学视野中彰显出其原生性和本体性,凸显出人的主体性;艺术价值在于育人和实践;艺术的本质是对宇宙结构秩序和形式秩序,及对人的精神秩序的模仿。从哲学视野审视艺术价值,更加丰富了艺术价值的内涵。首先,就艺术价值的人类本体论意义上说,"价值"本身带有艺术性、意义性、符号性和美学性的哲学观点;其次,艺术哲学中价值概念具有本质规定性,艺术价值具有内在规定性和抽象的本质特性;最后,艺术价值还有现实的多种体现形式。     

Efficacy observation on Governor Vessel-regulating and brain-unblocking acupuncture for post-stroke depression

Objective

To observe the clinical effect of Governor Vessel-regulating and brain-unblocking acupuncture on post-stroke depression.

Methods

A total of 70 eligible cases were randomly allocated into an observation group and a control group according to the random number table. Patients in the observation group were treated with Governor Vessel-regulating and brain-unblocking acupuncture, whereas patients in the control group were treated with oral Escitalopram Oxalate tablet. The treatment lasted for 8 weeks. The Hamilton depression scale (HAMD), Montgomery Asberg depression rating scale (MADRS), and Barthel Index (BI) were used to evaluate the patients’ condition before, 4 weeks and 8 weeks after treatment respectively. In addition, adverse reactions were also recorded.

Results

After 4 weeks of treatment, the HAMD and MADRS scores were significantly decreased in both groups (P<0.05); and the BI scores were significantly increased in both groups (P<0.05). There was no between-group statistical difference in HAMD score (P>0.05); the MADRS score in the observation group was significantly lower than that in the control group (P<0.05) and the BI score in the observation group was significantly higher than that in the control group (P<0.05). After 8 weeks of treatment, there were no between-group statistical differences in all aspects (P>0.05); however, the adverse reactions in the observation group were significantly less than those in the control group.

Conclusion

The Governor Vessel-regulating and brain-unblocking acupuncture is safe and effective for post-stroke depression and can obtain similar efficacy as Escitalopram Oxalate tablet. In addition, it can fast alleviate core symptoms of depression and improve the activities of daily living (ADL) and has fewer adverse reactions.

     

调督安神针法结合归脾汤治疗心脾两虚型不寐的疗效观察

目的:继承燕赵高氏针灸学术思想,观察调督安神针法治疗失眠的临床疗效。方法:76例心脾两虚失眠患者按随机数字表法随机分为2组,治疗组38例,对照组36例(2例脱落)。在口服归脾汤基础上,治疗组予调督安神针法针刺,对照组予普通针刺法,2组均治疗4周。采用匹兹堡睡眠质量指数(Pittsburgh Sleep Quality Index,PSQI)评价睡眠质量,匹兹堡睡眠质量指数减分率进行疗效评定。结果:2组治疗后在疗效上比较无统计学意义(P0.05),但治疗组治疗后PSQI减分率明显优于对照组(P0.05),治疗组治疗后PSQI睡眠质量、入睡时间和睡眠障碍方面的改善优于对照组(P0.05)。结论:调督安神针法结合归脾汤治疗心脾两虚失眠疗效确切,且不同腧穴组方和下针顺序可能是影响临床疗效的因素之一。     

氯通道对血小板活化标志物PAC-1和P-选择素的影响

目的：探讨氯通道对血小板活化标志物PAC-1和P-选择素的影响。方法：采用Western blot和免疫荧光技术检测ClC-3在人外周血来源的血小板上的表达;ADP(20μM)不同时间点(15、30、60、120、180 min)处理血小板后,Western blot检测ClC-3蛋白的表达变化;利用流式细胞术检测空白对照组, ADP组,DIDS(100μM)+ADP组,NFA(100μM)+ADP组,NPPB(100μM)+ADP和低氯对照组,低氯+ADP组的血小板活化分子标志物PAC-1和P-选择素的表达变化。结果：在健康成人外周血分离的血小板上表达ClC-3蛋白;ADP时间依赖性地处理血小板,ClC-3蛋白表达呈增加趋势,15 min相较于空白对照组已有统计学意义(P<0.05);ADP组PAC-1(32.13%±2.0%)及P-选择素(52.32%±5.31%)表达均高于空白对照组(1.76%±0.41%,1.89%±0.32%,P<0.01);低氯对照组PAC-1(8.01%±1.36%)和P-选择素(12.19%±0.84%)的表达与空白对照组相比,均上调(P<0.05);与ADP组PAC-1相比, DIDS+ADP(5.62%±1.22%),NFA+ADP(1.96%±0.54%)和NPPB+ADP(3.56%±0.79%)组表达降低,低氯+ADP组(45.26%±4.43%)表达增加(P<0.01);与ADP组P-选择素相比,DIDS+ADP(16.64%±1.52%), NFA+ADP(4.97%±0.64%)和NPPB+ADP(8.56%±2.04%)组表达均降低,低氯+ADP组(73.33%±3.80%)表达增加(P<0.01)。结论：人血小板上ClC-3氯通道参与血小板的活化,氯通道阻断剂抑制ADP诱导的血小板活化,降低血小板胞外氯浓度可促进ADP诱导的血小板的活化。     

一种连续性肾脏替代治疗置换液配液智能控制装置的设计

目的 :设计一种连续性肾脏替代治疗(continuous renal replacement therapy,CRRT)置换液配液智能控制装置。方法:该装置主要包括单片机、电磁阀、空气探测器、重力传感器、无线传输装置等,采用单片机智能控制系统通过无线传输装置控制电磁阀进行配液,同时利用空气探测器及重力传感器监控配液过程。结果:该装置能够根据不同患者的需求,精确配置个体化置换液。结论:该装置使用方便,可精确配制各种不同个性化置换液,有效降低医护人员的工作量,降低医疗成本,值得推广。     

费森尤斯4008S血液透析机故障维修两例

本文介绍了费森尤斯4008s血液透析机出现电导度F02报警及FLOW ALARM报警时故障分析及排除过程.     

联合捷然DROS-50AD透析用水处理产水量下降分析及处理

血液透析是维持肾衰竭患者生命的有效手段之一,血液透析患者每周血液需要与大量的透析液(300~400 L)交换。透析用水的水质及透析用水处理设备的稳定性至关重要。如水处理设备发生故障,整个透析中心将无法正常运行。我中心与2011年1月份引进联合捷然DROS-50AD双级反渗水处理系统。现将使用过程中出现产水