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Vignesh Pandiarajan Barman Prabal Basu Suprit Mondal Sanjib Ishran Bhoomika Kumrah Rajni Dod Aditya Garg Ravinder Rawat Amit Singh Surjit 《Immunologic research》2023,71(1):112-120
Immunologic Research - Juvenile dermatomyositis (JDM) is the commonest inflammatory myositis in children. The clinical phenotype is often characterized by the presence of myositis-specific... 相似文献
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A Young Child with Eosinophilia,Rash, and Multisystem Illness: Drug Rash,Eosinophilia, and Systemic Symptoms Syndrome After Receipt of Fluoxetine 下载免费PDF全文
Pandiarajan Vignesh M.D. Janak Kishore M.D. Ankur Kumar M.D. Keshavamurthy Vinay M.D. Sunil Dogra M.D. Sreejesh Sreedharanunni M.D. Prabhas Prasun Giri M.D. Priyankar Pal M.D. Apurba Ghosh M.D. 《Pediatric dermatology》2017,34(3):e120-e125
Drug rash, eosinophilia, and systemic symptoms (DRESS) syndrome is a severe systemic hypersensitivity reaction that usually occurs within 6 weeks of exposure to the offending drug. Diagnosis is usually straightforward in patients with pyrexia, skin rash, hepatitis, and eosinophilia with a preceding history of exposure to agents often associated with DRESS syndrome, such as aromatic anticonvulsants and sulfa drugs, but diagnosis of DRESS may still be a challenge. We report a 4‐year‐old child with probable DRESS syndrome complicated by multiple hematologic complications that developed 1 month after exposure to fluoxetine, a drug not known to be associated with such severe reactions. 相似文献
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Sclerosing cholangitis and intracranial lymphoma in a child with classical Wiskott–Aldrich syndrome 下载免费PDF全文
Pandiarajan Vignesh Deepti Suri Amit Rawat Yu Lung Lau Anmol Bhatia Ashim Das Anirudh Srinivasan Sivashanmugam Dhandapani 《Pediatric blood & cancer》2017,64(1):106-109
Patients with Wiskott–Aldrich syndrome (WAS) are predisposed to malignancy and autoimmunity in addition to infections. We report a male child with WAS, who had presented with recurrent pneumonia, eczema, thrombocytopenia, autoimmune hemolytic anemia, and vasculitic skin lesions. Genetic analysis revealed a classical genotype WAS 155C>T; R41X. At 2 years of follow‐up, he developed persistent headache and progressive hepatomegaly. Brain imaging showed a mass in the right frontal region, which on histopathology was shown to be high‐grade non‐Hodgkin lymphoma. Magnetic resonance cholangiopancreatography showed features of sclerosing cholangitis. This report extends the clinical spectrum and highlights unusual manifestations of sclerosing cholangitis and intracranial lymphoma in a patient with WAS. 相似文献
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Pandiarajan Vignesh Sagar Bhattad Manphool Singhal Surjit Singh 《Rheumatology international》2016,36(8):1191-1193
Epidemiological case definition of Kawasaki disease (KD) by the American Heart Association requires the presence of fever and four of the following: eye signs, oral mucosal changes, skin rashes, limb edema, and unilateral cervical lymphadenopathy. Incomplete KD is a well-known entity where there is lack of some of mucocutaneous features, and this occurs more often in infants. We report a 5-year-old boy with KD and giant coronary aneurysms, who presented only with fever and there is complete lack of skin and mucosal manifestations at presentation. 相似文献
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