排序方式: 共有18条查询结果,搜索用时 234 毫秒
1.
目的研究避光输液器在临床输注过程中与药物的相互作用以及安全性问题。方法通过对硝普钠、氟罗沙星以及盐酸阿扎司琼3种光敏性药物用避光输液器进行模拟临床输液试验,对流经输液器前后的药液的各项指标进行检测,并对增塑剂TOTM以及避光着色剂在输液过程中的迁移进行检测。结果药物溶液在光照条件下经过避光输液器前后各项指标并无明显变化。增塑剂TOTM与避光着色剂在输液过程中有微量溶出。结论避光输液器与试验药物相容性良好,输液管路中的TOTM与避光着色剂有微量溶出,应用一次性避光式输液器输注光敏感型药物安全可靠。 相似文献
2.
药用胶囊中合成着色剂的含量测定 总被引:1,自引:0,他引:1
目的检测药用胶囊中合成着色剂含量。方法高效液相色谱梯度洗脱法,流动相A为乙腈,B为0.02 mol·L-1乙酸铵,洗脱程序:0~5 min,A相浓度8%~18%,B相浓度92%~82%;5~12 min,A相浓度18%~74%,B相浓度82%~26%;12~15 min,A相浓度74%~74%,B相浓度26%~26%。流动相流速为1.0 mL·min-1,紫外检测波长254 nm,柱温25℃,进样量:10μL。结果药用胶囊中的合成着色剂回收率达93.2%~98.5%,精密度RSD在0.8%~3.0%,浓度范围在5~60 mg·L-1时有良好的线性关系。结论应用此方法可使合成着色剂得到很好分离,测定结果满意。 相似文献
3.
Min-Kyoung Kim Han-ah Kim Kwangoh Koh Hee-Seon Kim Young Sang Lee Yong Ho Kim 《Nutrition Research And Practice》2008,2(1):46-49
Anthocyanin pigments from varieties of black, red and wild rice were identified and quantified to evaluate their potential as nutritional function, natural colorants or functional food ingredients. Anthocyanin extraction was conducted with acidified methanol with 0.1M HCl (85:15, v/v) and identification of anthocyanin, aglycone and sugar moieties was conducted by comparison with purified standards by HPLC, Ultraviolet-Visible absorption spectrophotometer and paper chromatography. Black and wild rice showed three different types of pigments by HPLC whereas red rice variety did not show any anthocyanins. Out of three pigments detected, one (peak 2) was characterized as cyanidin-3-glucoside (C3G) by comparison of spectroscopic and chromatographic properties with an authentic standard, and another (peak 3) was tentatively identified as cyanidin-fructoside on the basis of spectroscopic properties with λmax of aglycone in 1% HCl methanol at 537 nm, electrospray ionization mass spectra with major ions at 449 and 287 m/z and chromatographic properties. But another pigment (peak 1) has not been characterized. The most abundant anthocyanin in black and wild rice was C3G. 相似文献
4.
以新鲜猪血为原料,分离血清,依次进行防腐、发色和抗氧化处理,制成浆状的无硝血红蛋白着色剂。它的优良性能,经紫外-可见光光谱测定测定存放和光照实验,得到了验证。 相似文献
5.
目的五味子的质量考察。方法对77批五味子作了性状、薄层色谱鉴别、含量测定和杂质等方面的检验。又用薄层色谱、高效液相色谱和二级管阵列等方法作了非法添加染色剂和杂质的检查。结果 77批五味子中有17批不合格,不合格率为22.1%。结论要加强五味子的内在质量管理,保证临床用药安全有效。 相似文献
6.
目的 观测不同配方的玻璃着色剂对可切削渗透陶瓷(MIC)复合体颜色的影响。方法 确定渗透玻璃基本组分。测定其光学指数:色散值0.068 41(435.8-656.3 nm),折射率1.596 91(587.6 nm波长)。以基本配方为核心调整形成5种着色剂配方的渗透玻璃。将它们渗透到氧化铝圆片状试件中,TC-PIIG型色差计分别测量5种MIC复合体的L*、a*、b*值并与Vita In-ceram陶瓷颜色系数比较。结果 不同着色剂配方的MIC颜色体系的的主要区别在L*值,其次是a*值,b*值变化较小。MIC颜色体系L*值为64.55-71.46,a*值为3.35-7.38,b*值为10.00-12.41,Ca*b*11.38-13.95,ha*b*54.07-73.00。与Vita In-ceram陶瓷色系颜色参数接近。结论 渗透玻璃着色剂配方的改变主要影响渗透陶瓷复合体颜色表达的明度和色相,对彩度的影响相对较小,其颜色表达符合临床应用要求。 相似文献
7.
8.
9.
Elisabeth Maier Katharina Kurz Marcel Jenny Harald Schennach Florian Ueberall Dietmar Fuchs 《Food and chemical toxicology》2010
Food preservatives sodium benzoate and propionic acid and colorant curcumin are demonstrated to suppress in a dose-dependent manner Th1-type immune response in human peripheral blood mononuclear cells (PBMC) in vitro. Results show an anti-inflammatory property of compounds which however could shift the Th1–Th2-type immune balance towards Th2-type immunity. 相似文献
10.