全文获取类型
收费全文 | 12338篇 |
免费 | 1426篇 |
国内免费 | 424篇 |
专业分类
耳鼻咽喉 | 196篇 |
儿科学 | 288篇 |
妇产科学 | 340篇 |
基础医学 | 1575篇 |
口腔科学 | 604篇 |
临床医学 | 1264篇 |
内科学 | 2079篇 |
皮肤病学 | 158篇 |
神经病学 | 833篇 |
特种医学 | 319篇 |
外国民族医学 | 3篇 |
外科学 | 1675篇 |
综合类 | 1061篇 |
现状与发展 | 2篇 |
一般理论 | 1篇 |
预防医学 | 765篇 |
眼科学 | 360篇 |
药学 | 1218篇 |
5篇 | |
中国医学 | 356篇 |
肿瘤学 | 1086篇 |
出版年
2023年 | 154篇 |
2022年 | 191篇 |
2021年 | 448篇 |
2020年 | 376篇 |
2019年 | 494篇 |
2018年 | 508篇 |
2017年 | 421篇 |
2016年 | 406篇 |
2015年 | 620篇 |
2014年 | 746篇 |
2013年 | 759篇 |
2012年 | 945篇 |
2011年 | 978篇 |
2010年 | 731篇 |
2009年 | 553篇 |
2008年 | 731篇 |
2007年 | 711篇 |
2006年 | 669篇 |
2005年 | 595篇 |
2004年 | 513篇 |
2003年 | 420篇 |
2002年 | 364篇 |
2001年 | 233篇 |
2000年 | 213篇 |
1999年 | 190篇 |
1998年 | 113篇 |
1997年 | 118篇 |
1996年 | 92篇 |
1995年 | 68篇 |
1994年 | 79篇 |
1993年 | 77篇 |
1992年 | 85篇 |
1991年 | 94篇 |
1990年 | 88篇 |
1989年 | 77篇 |
1988年 | 60篇 |
1987年 | 50篇 |
1986年 | 39篇 |
1985年 | 25篇 |
1984年 | 24篇 |
1983年 | 16篇 |
1982年 | 9篇 |
1981年 | 13篇 |
1980年 | 14篇 |
1979年 | 12篇 |
1978年 | 8篇 |
1977年 | 13篇 |
1976年 | 5篇 |
1975年 | 6篇 |
1974年 | 6篇 |
排序方式: 共有10000条查询结果,搜索用时 62 毫秒
1.
感染性疾病对老年人危害严重,接种疫苗是预防感染的有效手段。但我国常见感染性疾病疫苗的整体接种率偏低,基层医务人员及居民对疫苗接种的认知存在不足。《社区老年人常见感染性疾病疫苗应用专家共识》针对流感疫苗、肺炎球菌疫苗和带状疱疹疫苗3种常见疫苗的接种给予了详细的指导,旨在提高基层医务人员对老年人群疫苗接种的重视程度,加强其对公众的疫苗接种宣传教育,医防协同,共同助力提高老年人群健康水平。 相似文献
2.
3.
4.
Chi Yuen Cheung Mei Lan Pong Suk Fun Au Yeung Wai Leung Chak 《Transplantation proceedings》2021,53(4):1143-1145
IntroductionThe coronavirus disease 2019 (COVID-19) pandemic was expected to have a negative impact on organ donation. With the differences in health care systems and lockdown policies in various regions, the pandemic's effect on organ donation and transplant service may vary. Most of the deceased donor organ referrals in our hospital came from non–intensive care units (ICUs). The objective of this study is to report our experience and quantify the effects of the COVID-19 pandemic on deceased donor organ donation in our center.MethodsThis was a retrospective observational study comparing the deceased donor organ donation activity during the period January 23 to November 30, 2020 with the same period in 2018 in Queen Elizabeth Hospital, Hong Kong.ResultsThere was a 26.9% reduction in deceased donor organ donor referral in 2020 compared with 2018. No significant difference in the proportion of referrals from ICU or non-ICU areas between the 2 time periods was observed. The brain death confirmation rate was significantly higher in 2020 (40.8% vs 20.2%, P = .003). Nine patients had family consent for organ donation in 2020 (vs 7 patients in the same period in 2018). There were no significant differences in consent rate and number of recovered organs between the 2 periods.ConclusionsWith effective measures to limit the spread of COVID-19 in a community, it is possible to support the needs of both patients with COVID-19 and deceased donor organ donation services. 相似文献
5.
Background
The significance of a positive culture at reimplantation remains an important topic of consideration given the lack of clear metrics for when reimplantation can be performed. The purpose of this study is thus to investigate the (1) association between a positive culture during reimplantation and failure following 2-stage exchange arthroplasty and the (2) influence of prolonged antibiotics on these patients.Methods
We retrospectively reviewed 117 patients undergoing 2-stage exchange hip arthroplasty from 2012 to 2016. Of them, 23 had positive culture during reimplantation and were treated with 2 weeks of intravenous and 4 weeks of oral antibiotics following reimplantation. All patients had a minimum follow-up of 1 year. Logistic regression models were performed to identify association between positive culture and subsequent treatment failure. A meta-analysis was also performed to validate findings. A subgroup analysis was performed to explore whether 6-week antibiotics (oral, intravenous, or both) after reimplantation improved outcomes.Results
A total of 11 studies, which included 141 cases with a positive culture at reimplantation and 784 with negative cultures, were included in the meta-analysis. The pooled data showed a higher risk of failure in patients with a positive culture than those with a negative culture (41.1% vs 14.8%, odds ratio 4.58). The subgroup analysis revealed that 6 weeks of antibiotic administration following reimplantation decreased the odds of reinfection from 9.35 to 3.12. The findings in the retrospective cohort were consistent with those of the meta-analysis; the failure rate was significantly higher in patients with a positive culture than those with negative cultures (26.1% vs 6.4%, P < .001).Conclusion
Six weeks of antibiotics appear to decrease the odds of reinfection after reimplantation. However, despite patients receiving 6 weeks of antibiotics after reimplantation, the risk of reinfection in patients with a positive culture at reimplantation is still more than 3 times higher than those with negative cultures. Further studies are needed to investigate optimal management for such patients. 相似文献6.
7.
Gerald Chi Adeel Jamil Umer Jamil Muhammad A. Balouch Jolanta Marszalek Farima Kahe 《Clinical and experimental hypertension (New York, N.Y. : 1993)》2019,41(2):160-167
Background: Intensive blood pressure (BP) lowering may offer protective effects against major adverse cardiac event (MACE) but is also associated with a greater risk of a serious adverse event (SAE). The risk-benefit profile of intensive versus standard BP control has not been comprehensively assessed. Methods: Four studies were identified from a systematic literature search for randomized controlled trials comparing intensive versus standard BP lowering that reported both MACE and SAE endpoints. A previously described statistical approach was applied to characterize the efficacy-safety tradeoff of BP control. The bivariate outcome was computed to quantitatively assess the net clinical benefit (NCB) of intensive BP lowering as compared to standard treatment, with positive values indicating increased risks and negative values indicating decreased risks. Results: Data from the SPRINT trial demonstrated that intensive strategy was superior in MACE but inferior in SAE, thereby eroding the NCB (bivariate outcome: 0.33% [?0.50% to 1.21%]). Intensive strategy from the SPS3 trial fulfilled non-inferiority in both MACE and SAE but did not reach a favorable NCB (?1.31% [?2.25% to 0.01%]). The ACCORD trial suggested that intensive strategy was non-inferior in MACE but inferior in SAE (?0.19% [?0.79% to 1.37%]). Results from the VALISH trial were inconclusive for SAE but suggested non-inferiority in MACE (?1.19% [?3.24% to 0.68%]). Conclusions: Compared to the standard blood pressure target, pooled data from randomized controlled trials suggest that intensive strategy did not achieve a net clinical benefit when weighing the benefit of MACE reduction against the risk of SAE under the bivariate framework.Abbreviations: Blood pressure (BP), diastolic blood pressure (DBP), major adverse cardiac event (MACE), net clinical benefit (NCB), serious adverse event (SAE), systolic blood pressure (SBP). 相似文献
8.
Chih‐Tsung Hung Chien‐Ping Chiang Chi‐Hsiang Chung Chang‐Huei Tsao Wu‐Chien Chien Wei‐Ming Wang 《The Journal of dermatology》2019,46(2):110-116
Rosacea has been reported to be associated with psychiatric disorders. Nevertheless, a nationwide study of the relationship between rosacea and comorbid psychiatric diseases in an Asian population has not been conducted. The aim of this study was to clarify the role of rosacea in the various psychiatric disorders by using a nationwide database in Taiwan. Data were obtained from the National Health Insurance Research Database of Taiwan from 2000 to 2013. In total, 7881 patients with rosacea and 31 524 age‐ and sex‐matched controls were enrolled. Patients with rosacea tended to have more coexisting psychiatric disorders. After adjusting for age, sex, comorbidity and residence/regions, the adjusted hazard ratio (HR) of psychiatric disorders for patients with rosacea was 2.761 (95% CI = 2.650–2.877, P < 0.001). Among them, the highest adjusted HR are phobic disorder and obsessive–compulsive disorder of 7.841 (95% CI = 7.526–8.170, P < 0.001) and 6.389 (95% CI = 6.132–6.657, P < 0.001), respectively. The National Health Insurance Research Database of Taiwan does not include the information about rosacea subtypes, severity and laboratory parameters. In conclusion, rosacea is related to various psychiatric disorders. In addition to anxiety and depression, patients are also at increased risk of phobic disorder and obsessive–compulsive disorder. 相似文献
9.
Jae Eun Choi Tyler Werbel Zhenping Wang Chia Chi Wu Tony L. Yaksh Anna Di Nardo 《Journal of dermatological science》2019,93(1):58-64