首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   2707篇
  免费   122篇
  国内免费   24篇
耳鼻咽喉   6篇
儿科学   251篇
妇产科学   179篇
基础医学   211篇
口腔科学   13篇
临床医学   362篇
内科学   146篇
皮肤病学   28篇
神经病学   47篇
特种医学   136篇
外科学   753篇
综合类   271篇
预防医学   76篇
眼科学   31篇
药学   164篇
中国医学   20篇
肿瘤学   159篇
  2024年   3篇
  2023年   28篇
  2022年   66篇
  2021年   116篇
  2020年   119篇
  2019年   96篇
  2018年   91篇
  2017年   75篇
  2016年   72篇
  2015年   80篇
  2014年   170篇
  2013年   146篇
  2012年   123篇
  2011年   157篇
  2010年   116篇
  2009年   146篇
  2008年   136篇
  2007年   115篇
  2006年   134篇
  2005年   99篇
  2004年   93篇
  2003年   96篇
  2002年   61篇
  2001年   45篇
  2000年   40篇
  1999年   37篇
  1998年   35篇
  1997年   29篇
  1996年   35篇
  1995年   24篇
  1994年   27篇
  1993年   28篇
  1992年   13篇
  1991年   20篇
  1990年   16篇
  1989年   19篇
  1988年   16篇
  1987年   16篇
  1986年   8篇
  1985年   19篇
  1984年   21篇
  1983年   8篇
  1982年   14篇
  1981年   8篇
  1980年   5篇
  1979年   8篇
  1978年   7篇
  1977年   3篇
  1976年   5篇
  1974年   5篇
排序方式: 共有2853条查询结果,搜索用时 31 毫秒
1.
2.
PurposeFew investigations have examined the production of single restorations using intraoral scanners (IOS). Data on full-arch scans are rare, and data regarding torsion within the entire arch are very sparsely reported. Therefore, the aim of this study was to examine the deviations of torsion and linear distances in full-arch scans of three IOS based on different scanning principles.MethodsA cobalt-chrome-molybdenum alloy master model (CCMM) with four hemispheres was fabricated by laser sintering. The CCMM was digitized using a laboratory scanner (ATOS-Core/GOM) and scanned with three IOS (Omnicam/Sirona(OC); True Definition/3M(TD); TriosII/Cara-Version/Kulzer(TR)). All scan data were exported in a standard STL-file format and were analyzed with GOM Inspect software (V7.5/GOM). Torsion between the right and left side of the arch and linear accuracy (trueness and precision) were evaluated. After normality was confirmed, all data were subjected to parametric statistical analyses.ResultsThe torsion ranged from 0.07 ± 0.03°(OC) to 0.29 ± 0.14°(TD). Pairwise comparisons showed significant differences between the OC and TD scanners and between the TR and TD scanners. The linear distances ranged from 6 ± 5 μm(OC) to 298 ± 317 μm(TD). Significant differences were observed among all investigated IOS (p = 0.05).ConclusionsAlthough the highest torsion was observed for the TD scanner, it is still not clear whether the differences between the IOS are related to the scanning principle or to the scanning algorithm. Due to the high clinical relevance of full-arch restorations, future studies should consider torsion. Regarding linear accuracy, no general difference related to the scanning principles of the IOSs was observed.  相似文献   
3.
4.
Objectives: The present study aims to evaluate the role of Positron emission tomography (PET) -computed tomography (CT) with 18F-fluorodeoxyglucose (18F-FDG) in the restaging of high-risk testicular cancer. Methods: Forty-five patients (mean age of 38.1±11.3 years and range 23-81 years) with testicular carcinoma, underwent 18F-FDG PET-CT during their clinical course were prospectively selected. PET positivity was defined as a site of abnormal 18F-FDG uptake in tissue histologically proven or clinically or radiographically suspected to represent tissue involvement. The sites of disease were characterized as either nodal or extranodal. All patients were followed-up for at least 12 months with a diagnostic and/or functional imaging modality. Results: Of the 45 patients 38 (84%) patient presented with seminoma and 7 (16%) were Non-seminomatous germ cell tumors. Analysis of secondary disease spectrum showed nodal involvement in 65%, osseous involvement in 23% and mixed visceral/soft tissue lesions in 12% of patients. Nineteen (42%) were negative for any metastatic disease. All negative patients remain disease free in the follow-up of one year. Out of the positive 26/45 patients, PET-CT showed progressive disease in 3/26, stable disease 1/26 and partial response in 2/26 and complete metabolic resolution in 20/26 patients. 18F-FDG PET-CT was able to characterize all patients leading to significant change of primary decision of wait and watch to go for treatment and vice versa. Conclusion: 18F-FDG PET-CT scan is potentially an excellent tool for characterization of equivocal lesions on CT scan in the restaging settings and follow up of high-risk testicular cancer patients.  相似文献   
5.
睾丸扭转和精索扭转的诊断与治疗(附68例报告)   总被引:9,自引:0,他引:9  
目的:探讨睾丸和精索扭转的诊断与治疗方法,提高睾丸和精索扭转的治疗水平。方法:对68例睾丸和精索扭转的临床资料进行总结,68例平均年龄21岁,<20岁者占84%,左侧55例占80.8%.发病至确诊时间6h~30天,12h以上者占90.2%。结果:53例术前彩色多普勒血流动态显象(CDFI)应作为诊断疾病的常见与首选检查方法。诊断并经手术证实,符合率100%,经手术探查;41例行手术复位、固定,睾丸获救。27例行患侧睾丸切除术,所有病例均行对侧探察,固定。结论:阴囊X核素显象,B超对睾丸精索扭转早期诊断有帮助。早期诊断,及时治疗是提高疗效的关键。彩色多普勒血流动态显象应作为诊断该疾病的常见及首选检查方法,对睾丸精索一旦确诊或疑有精索扭转的患者应及早行紧急复位,以期挽救睾丸,同时行睾丸固定术也十分必要。对于确诊毫无保留价值的睾丸需行切除术。  相似文献   
6.
Lobar torsion is reported as very rare but sometimes catastrophic complication if overlooked during the early postoperative period following a lobectomy, though it is totally preventable. In this novel technique, a piece of parietal pleural flap is harvested from the posterior wall of the chest using a hook diathermy while keeping its upper border as close to the apex as possible. Finally, distal end of the flap is secured to the upper edge of the lobe using a fine monofilament absorbable suture. This procedure not only protects the lobe from rotation but also maintains continuous expansion of the lung in the early postoperative period and may, therefore, be a good option to prevent such a serious complication in selected patients following a lobectomy.  相似文献   
7.
Torsions of the spermatic cord occurring from the intrauterine period to the end of the first year of life are termed perinatal. These are divided into prenatal and postnatal torsions, depending on their occurrence in the intrauterine or postuterine period. From January 1984 to January 1996, 6 cases were identified at our institution, involving 4 prenatal and 2 postnatal extravaginal torsions of the spermatic cord. These cases are reviewed with regard to optimal therapeutic approaches for the treatment of both the affected gonad as well as the contralateral one, and whether the event occurred prenatally or postnatally. The authors also propose several clinical indications useful for obstetricians, pediatricians, urologists and nurses.  相似文献   
8.
精索扭转误诊24例分析   总被引:5,自引:0,他引:5  
目的:分析精索扭转误诊的原因及教训,提高临床医生对该病的认识水平与警惕性,以减少误诊的发生。方法:对24例外院误诊的精索扭转病例进行回顾性分析。结果:24例患者均经手术证实为精索扭转,因未能及时诊断,延误时机而切除缺血坏死的睾丸。结论:彩色多普勒血流动态显像应作为诊断该疾病的常规与首选检查方法,对精索扭转一旦确诊或疑有精索扭转的患者应及早行紧急复位,以期挽救睾丸。同时行睾丸固定术也十分必要,对于确诊毫无保留价值的睾丸需行切除。  相似文献   
9.
目的:探讨己酮可可碱(PTX)对大鼠睾丸扭转复位后生精功能的保护作用。方法:雄性SD大鼠24只,随机分成3组,每组8只,建立睾丸扭转动物模型。第Ⅰ组为假手术组(扭转720°后立即复位),第Ⅱ、Ⅲ组扭转720°2 h,于复位前15 m in分别静脉注射生理盐水和PTX,术后24 h留取手术侧睾丸。应用流式细胞术(FCM)检测各组生精细胞凋亡和各级生精细胞计数,采用硫代巴比妥酸法测定丙二醛(MDA)含量,化学比色法测定组织内总抗氧化能力(T-AOC)。结果:第Ⅲ组应用PTX后与第Ⅱ组相比,生精细胞凋亡明显减少(399.50±33.31vs1221.75±132.48,P<0.01),单倍体和四倍体细胞群计数显著增多(5554.13±441.28vs4102.35±206.98;1906.00±200.72vs1711.63±144.55,P均<0.01;),T-AOC明显回升(32.52±2.86vs22.76±3.73,P<0.01),MDA含量下降(1.78±0.20vs3.98±0.36,P<0.01),其差异均有显著性(P<0.01)。结论:己酮可可碱对睾丸扭转复位后的生精功能具有明显的保护作用。  相似文献   
10.
彩色多普勒超声在精索扭转诊断和鉴别诊断中的价值   总被引:8,自引:1,他引:7  
目的 :应用彩色多普勒超声鉴别精索扭转和急性睾丸炎。 方法 :回顾性分析 13例急性睾丸疼痛病人的彩色多普勒血流显像 (CDFI)表现和治疗情况。 结果 :8例显示睾丸内血流信号稀疏或消失 ,诊断为精索扭转 ,其中 1例手法复位成功 ,7例手术探查并得以证实。其余 5例显示患侧睾丸血流信号丰富 ,诊断为急性睾丸炎或睾丸附睾炎 ,经抗生素治疗后症状好转 ,超声复查显示血流减少。 结论 :CDFI在精索扭转诊断和鉴别诊断中具有重要意义 ,可作为急性睾丸疼痛病人的首选检查方法  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号