全文获取类型
收费全文 | 18492篇 |
免费 | 1440篇 |
国内免费 | 1414篇 |
专业分类
耳鼻咽喉 | 981篇 |
儿科学 | 273篇 |
妇产科学 | 392篇 |
基础医学 | 472篇 |
口腔科学 | 113篇 |
临床医学 | 5250篇 |
内科学 | 4671篇 |
皮肤病学 | 89篇 |
神经病学 | 504篇 |
特种医学 | 758篇 |
外国民族医学 | 3篇 |
外科学 | 2870篇 |
综合类 | 2818篇 |
预防医学 | 465篇 |
眼科学 | 215篇 |
药学 | 699篇 |
7篇 | |
中国医学 | 102篇 |
肿瘤学 | 664篇 |
出版年
2024年 | 70篇 |
2023年 | 546篇 |
2022年 | 724篇 |
2021年 | 923篇 |
2020年 | 900篇 |
2019年 | 916篇 |
2018年 | 673篇 |
2017年 | 574篇 |
2016年 | 687篇 |
2015年 | 787篇 |
2014年 | 1305篇 |
2013年 | 1196篇 |
2012年 | 952篇 |
2011年 | 1201篇 |
2010年 | 1031篇 |
2009年 | 903篇 |
2008年 | 940篇 |
2007年 | 977篇 |
2006年 | 1008篇 |
2005年 | 824篇 |
2004年 | 688篇 |
2003年 | 626篇 |
2002年 | 543篇 |
2001年 | 468篇 |
2000年 | 288篇 |
1999年 | 250篇 |
1998年 | 213篇 |
1997年 | 172篇 |
1996年 | 166篇 |
1995年 | 145篇 |
1994年 | 123篇 |
1993年 | 71篇 |
1992年 | 77篇 |
1991年 | 72篇 |
1990年 | 78篇 |
1989年 | 45篇 |
1988年 | 37篇 |
1987年 | 31篇 |
1986年 | 19篇 |
1985年 | 8篇 |
1984年 | 18篇 |
1983年 | 14篇 |
1982年 | 14篇 |
1981年 | 7篇 |
1980年 | 8篇 |
1979年 | 4篇 |
1978年 | 9篇 |
1977年 | 8篇 |
1975年 | 4篇 |
1973年 | 1篇 |
排序方式: 共有10000条查询结果,搜索用时 16 毫秒
1.
2.
《Acta otorrinolaringologica espanola》2022,73(5):279-285
Background and objectiveMinimally invasive surgery of benign middle ear tumours is possible by using the endoscope. The optimal lighting and the broadest vision it offers, allow a transcanal approach to these rare tumours. The objective of this work is to summarize its key points through a case series.Materials and methodsRetrospective study of benign middle ear tumours that underwent exclusive endoscopic surgery in a third-level adult university hospital between June 2018 and June 2020. Postoperative follow-up was performed by otoendoscopy and audiometry.ResultsSix patients underwent surgery during the study period. Five patients were female and one male, with an average age of 57.8 years (± 21.9). Four tumours were in the left ear and 2 in the right ear. These included 4 tympanic paragangliomas (3 type I and one type II), a chorda tympani neuroma, and a congenital cholesteatoma. There were no serious postoperative complications. At present, no tumour recurrence has been found in either case, with a minimum follow-up of 7 months.ConclusionsThe present study adds evidence on the safety and efficacy of endoscopic transcanal ear surgery, as a minimally invasive technique, for the treatment of benign middle ear tumours confined to the tympanic cavity. 相似文献
3.
4.
目的 观察超声引导下关节腔内注射重组人Ⅱ型肿瘤坏死因子受体-抗体融合蛋白(益赛普)治疗血友病性关节病(HA)的价值。方法 回顾性分析32例接受超声引导下穿刺关节腔注射益赛普的HA患者,对比观察治疗前及治疗后1个月血友病关节健康评分(HJHS)、视觉模拟评分(VAS),以及超声所示目标关节增生滑膜厚度、血流信号、Melchiorre及中国早期血友病性关节病超声检测(HEAD-US-C)评分,评估其治疗价值。结果 对32例均成功完成超声引导下穿刺关节腔及腔内注射益赛普,共对18例膝关节、7例肘关节及7例踝关节进行治疗。术后未出现感染、出血等并发症。治疗后1个月,目标关节HJHS、VAS、Melchiorre评分、HEAD-US-C评分及增生滑膜最大厚度、平均厚度、血流信号均低于治疗前(P均<0.01)。结论 超声引导下关节腔内注射益赛普治疗HA安全、有效。 相似文献
5.
6.
7.
8.
《European journal of surgical oncology》2022,48(6):1264-1271
BackgroundIn order to avoid excessive treatment of thyroid nodules in the clinic, it is necessary to find a simple and practical analysis method to comprehensively and accurately reflect benign or malignant thyroid nodules. This study aimed to construct and validate a comprehensive and reliable network-based predictive model using a variety of imaging and laboratory criteria for thyroid nodules to stratify the risk of malignancy prior to surgery.MethodsWe retrospectively analyzed data from patients who underwent surgical treatment for thyroid nodules at the Thyroid and Breast Diagnosis and Treatment Center of Weifang Hospital of Traditional Chinese Medicine between January 2018 and December 2020. Binary logical regression analysis was performed to predict whether nodules were malignant or benign. The developmental dataset included 457 patients (January 2018–December 2020). The validation set included separate data points (n = 225, January 2018–December 2020).ResultsIn this study, criteria that showed significant predictive value for malignant nodules included TI-RADS: 4b (p = 0.065); Bethesda IV, Bethesda V, Bethesda VI (P < 0.0001); BRAFV600E mutation (P < 0.0001); Calcitonin>5 pg/ml (p = 0.0037); and FNA-Tg>30 ng/ml (p = 0.0003). A 10-grade risk scoring system was developed. The risk of malignancy risk ranged from 2.06% to 100% and was positively associated with increasing risk grade. The areas under the receiver-operating characteristic curve of the development and validation sets were 0.972 and 0.946, respectively.ConclusionA simple, comprehensive and reliable web-based predictive model was designed using a variety of imaging and laboratory criteria to stratify thyroid nodules by probability of malignancy. 相似文献
9.
《Revista brasileira de otorrinolaringologia (English ed.)》2022,88(4):602-606
IntroductionThe Modena bleeding score is a categorical rating scale that allows the assessment of the surgical field in relation to bleeding during endoscopic surgery. It has recently been presented and validated in the field of endoscopic ear surgery by the present authors. The Modena bleeding score provides five grades for rating the surgical field during endoscopic procedures (from grade 1 ? no bleeding to grade 5 ? bleeding that prevents every surgical procedure except those dedicated to bleeding control).ObjectiveThe aim of this study was to validate the Modena bleeding score in the setting of endoscopic sinus surgery.MethodsFifteen three-minute videos of endoscopic sinus surgery procedures (each containing three bleeding situations) were evaluated by 15 specialists, using the Modena bleeding score. Intra and inter-rater reliability were assessed, and the clinical validity of the Modena bleeding score was calculated using a referent standard.ResultsThe data analysis showed an intra-rater reliability ranging from 0.6336 to 0.861. The inter-rater reliability ranged from 0.676 to 0.844. The clinical validity was α = 0.70; confidence limits: 0.64 ? 0.75, corresponding to substantial agreement.ConclusionThe Modena bleeding score is an effective method to score bleeding during endoscopic sinus surgery. Its application in future research could facilitate the performance and efficacy assessment of surgical techniques, materials or devices aimed to bleeding control during endoscopic sinus surgery. 相似文献
10.