Effects of combined Chinese drugs and chemotherapy in treating advanced non-small cell lung cancer

Objective:To evaluate the efficacy and side effects of combined Chinese drugs and chemotherapy in treating advanced non-small cell lung cancer(NSCLC).Methods:Sixty-three patients with stageⅢB andⅣNSCLC hospitalized from October 2001 to October 2008 were enrolled and assigned to two groups using a randomizing digital table,with 33 patients in the treatment group and 30 in the control group. They were all treated with the Navelbine and Cisplatin(NP) chemotherapy,but to the treatment group the Chinese drugs...     

中医护理干预在胃脘痛治疗中的效果观察

目的探讨中医护理干预在治疗胃脘痛中的效果观察.方法对89例胃脘痛患者随机分成干预组和对照组,干预组采取中医穴位按压、中药外敷、穴位艾灸等综合干预,对照组采用常规护理方法.结果44例胃脘痛患者通过中医穴位按压、中药外敷、穴位艾灸综合干预,解除了患者痛苦,缩短了疗程,收到较好治疗效果.结论中医护理干预大大提高胃脘痛患者的治愈率.患者易于接受,疗效快,效果好.     

中医与西医治疗晚期非小细胞肺癌病人远期生存率的临床研究

Objective： To investigate the prognostic influence on long-term overall survival （OS） from treatment with Chinese medicine （CM） and chemotherapy or targeted therapy in advanced non-small-cell lung cancer （NSCLC） patients. Methods： The clinical data of 206 advanced NSCLC patients who were treated with CM and Western medicine in Beijing Cancer Hospital from April 1999 to July 2013 were retrospectively analyzed. Long-term survivors were defined as OS ≥ 3 years after treatment with CM and chemotherapy. Twenty-eight patients had OS ≥ 3 years, 178 had OS 〈 3 years, and all clinical data were statistically analyzed with the Cox model. Variables were gender, age, smoking status, performance status （PS） score, pathological type, clinical stage, first-line chemotherapy, targeted therapy, and use of CM. Univariate survival analysis was performed using the Kaplan-Meier method and log-rank sequential inspection. Multivariate survival analysis was used to analyze the meaningful factors of univariate survival analysis with the Cox model. Results： The survival rate of patients with OS ≥ 3 years was 13.6% （28/206）. Cox multivariate regression analysis showed that PS score, clinical stage, disease control rate to first-line chemotherapy, and use of CM were independent factors of long- term OS （all P〈0.05）. However, gender, age, smoking, and use of epidermal growth factor receptor tyrosine- kinase inhibitor were not significant （P〉0.05）. Conclusion： PS score, clinical stage, disease control rate to first- line chemotherapy, and use of CM are probably independent prognostic factors for long-term OS in patients with advanced NSCLC.     

肿瘤患者如何养生防感冒

很多患者来就诊时常会问这样一个问题:我老爱感冒有什么办法预防吗?生活上应注意些什么? 肿瘤患者,特别是多次化疗后,免疫力较低,怕风怕冷.除了必要的药物治疗外,向大家简单介绍一下<内经>中的顺应四时的自然养生法.     

肺癌初诊患者的中医证候分布规律研究

目的探讨初诊肺癌的中医证候分布规律。方法采用横断面研究方法,将符合纳入标准的肺癌初诊病例按八纲、气血及脏腑辨证进行分型并进行统计学处理分析。结果共收集139例肺癌初诊患者,其不同中医证候的分布组间差异有统计学意义（P〈0．01）。结论初诊肺癌最常见为气虚证、阴虚证或气阴两虚证,在虚证的基础上多易合并气滞证、血瘀证、痰湿证等兼夹证;肺癌病位在肺,最易累及肾、脾。     

Could We Use Clinical Benefit to Evaluate the Effects of Chinese Medicine on the Treatment of Cancer?

<正>Chinese medicine (CM) exhibits special characteristics and unique superiority in the cancer treatment,mainly showing in the alleviation of the side effects of radiotherapy and chemotherapy,such as the arrest of bone marrow and gastrointestinal     

互补/替代医学在癌症治疗中的现状与趋势──首届草药与癌症治疗国际会议落下帷幕

首届草药与癌症国际会议于2001年6月8～9日在意大利佛罗伦萨召开。来自美国国立卫生院（NIH）国家互补医学中心的教授，WHO国际药物检测中心，传统医学项目的负责人，意大利、中国、土尔其、奥地利、印地安、古巴、澳大利亚等10余个国家，150多名代表参加了会议。 与会代表对草药在癌症治疗中的作用，研究状况及今后的方向等展开了热烈的讨论。使用广泛的药物带有肿瘤治疗的终点性研究，如生存期，无病生存期，神经内分泌指标，神经心理社会性因素，生理功能和生活质量。特殊人群和各种CAM模式的题目：草药（人参，美黄芩，黑升麻），草…     

直肠癌合并皮肌炎1例

患者女性，６７岁，因面部、四肢皮疹２月余，近端肌无力１个月，便血半个月。于１９９７年６月就诊于北医大第一临床医院皮肤科，查体：两颊、前额、胸背部、四肢伸侧出现暗红色斑。丘疹，指间及掌指关节处可见Ｇｏｔｔｒｏｎ征，近端肌力下降，肌电图示肌损害，实验室指标异常：ＣＰＫ ３ ３００ＩＵ／Ｌ。ＬＤＨ５６３１Ｕ／Ｌ、ＧＯＴ１７８ＩＵ／Ｌ、ＧＰＴ １６３ＩＵ、ＡＮＡ：阳性１：１６０斑点型，胸片、心电图、腹部Ｂ超未见异常。确诊为皮肌炎。遂给予强的松６０ｍｇ／ｄ，治疗１０天后面部、四肢红斑、实验室指标明显好转，但…     

岩白菜素药源植物资源研究进展

岩白菜素具有镇咳祛痰的功效,作为传统用于治疗呼吸系统疾病的特效药,市场需求量大.目前已有20科37属88种植物均含有岩白菜素的研究报道,其中虎耳草科鬼灯檠属、岩白菜属、落新妇属,紫金牛科紫金牛属植物较为普遍,西南鬼灯檠、羽叶鬼灯檠和岩白菜是提取岩白菜素的主要植物资源,含有3.0%以上的岩白菜素.我国西南和西北地区是岩白菜素药源植物资源的主要分布区,但近年来野生资源迅速减少,有必要开展主要药源植物的保护与繁育及种植研究.     

玻璃体腔注射康柏西普对PDR玻璃体切割的辅助作用

背景 玻璃体切割术(PPV)是糖尿病视网膜病变增生晚期的主要治疗方法,研究表明PPV术前注射抗血管内皮生长因子(VEGF)药物能够有效降低手术难度及并发症的发生率,目前关于康柏西普在PPV术前辅助应用的报道尚少见. 目的 观察术前玻璃体腔注射康柏西普(IVC)对增生性糖尿病视网膜病变(PDR)患者行经平坦部PPV的辅助效果.方法 采用非随机对照临床研究,纳入2015年6月至2016年5月于粤北人民医院确诊并行PPV的PDR患者47例51眼的病例资料.依据术前是否行IVC将患者分为IVC组24例26眼和对照组23例25眼.对比分析2个组患者术中医源性裂孔的发生率、玻璃体腔填充物的应用和术后玻璃体再出血、黄斑中心凹视网膜厚度及最佳矫正视力(BCVA). 结果 术中IVC组患眼医源性裂孔发生率为7.69％,明显低于对照组的32.00％,差异有统计学意义(P=0.038);术中IVC组患眼应用玻璃体腔填充物的比例为19.23％,明显低于对照组的52.00％,差异有统计学意义(x2=5.993,P=0.014);术后4个月时IVC组玻璃体再出血的发生率为3.85％,明显低于对照组的28.00％,差异有统计学意义(P=0.024);术后3个月时IVC组黄斑中心凹视网膜厚度为(278.04±43.46) μm,明显较对照组的(340.76±84.91) μm薄,差异有统计学意义(t=-3.340,P=0.002);术后3个月时IVC组BCVA明显好于对照组,差异有统计学意义(Z=-2.114,P=0.034).IVC术后未见不良反应. 结论 术前IVC能减少PDR患者PPV术中医源性裂孔的发生及玻璃体腔填充物的应用,降低术后玻璃体腔再出血的发生率及黄斑中心凹视网膜厚度,并可提高患者的视力.