以传染源控制为主的血吸虫病综合防治策略文献计量学研究

目的 目的 对以传染源控制为主的血吸虫病综合防治策略产出进行文献计量学分析。 方法 方法 在中国知网 （CNKI）、 万方数据库、 维普数据库 （VIP）、 PubMed、 Web of Science、 BIOSIS和Google Scholar 等数据库中检索有关以传染源控制为 主的血吸虫病综合防治策略的文献, 并进行相关文献计量学分析。 结果 结果 2004?01?01至2014?09?30共发表94篇有关以 传染源控制为主的血吸虫病综合防治策略, 其中中文文献78篇, 占82.98%; 英文文献16篇, 占17.02%。中文文献共发表 在21种期刊上,《中国血吸虫病防治杂志》 发表论文最多, 占全部文献的37.23%; 16篇英文文献发表在12种英文期刊上, 其中 《PLoS Neglected Tropical Diseases》 刊载论文最多, 为3篇。94篇文献著者隶属于37家机构, 其中中国疾病预防控制 中心寄生虫病预防控制所 （16篇）、 安徽省血吸虫病防治研究所 （12篇）、 湖南省血吸虫病防治所 （9篇） 发文量居前3位; 94篇文献共有157位署名作者, 其中汪**、 周**、 张**发文量居前3位。 结论 结论 以传染源控制为主的血吸虫病综合防治 策略已在全国广泛推广实施, 应加大经验总结, 并积极向国际上宣传已取得的成果。     

控制传染源为主的综合策略在洞庭湖区血吸虫病防治中的实践与思考

湖南省通过4种模式试点,实施以控制传染源为主的综合防治血吸虫病策略,取得了明显效果。     

贵州省流行性出血热流行病学研究

本文报告贵州省1962至1987年在50县(市)有EHF病例发生:51县(市)人群血清中查到EHF抗体;高、低发病县(市)及一些未报病县的健康人群中存在有隐性感染;黔北的遵义等地为贵州省EHF高发病地区。全省82县(市)中,76县(市)的鼠类等携带EHF病毒;黔北的遵义等37县(市)主要是黑线姬鼠带病毒,东、南部的石阡等39县(市)则以褐家鼠带病毒为主;从人和鼠中分离到9株病原体。从而认为贵州省存在野鼠型、家鼠型及混合型EHF疫区,为本病防制对策的制定提供了科学依据。     

温肝法的学术渊源及方药整理研究

通过整理历代医家主要著作中关于温肝法的记载,阐述温肝法的学术渊源。运用计量学方法,选取文献中温肝法常用方药,建立数据库,进行药物频次统计,总结出温肝法高频药物和温肝法所治病证的治疗原则,以期更好的指导临床。     

Neural correlates of chromostereopsis: An evoked potential study

Chromostereopsis is an illusion of depth arising from colour contrast: ocular chromatic aberrations usually make red appear closer to the viewer than blue. Whereas this phenomenon is widely documented from the optical and psychophysical point of view, its neural correlates have not been investigated. To determine the cortical processing of this colour-based depth effect, visual evoked potentials (VEPs) to contrasts of colour were recorded in 25 subjects. Chromostereopsis was found with the stimuli combining spectra extremes. VEP amplitude but not latency effects were observed to colour depth cues, suggesting an underlying, depth-specific slow negative wave, located using source modelling first in occipito-parietal, parietal, then temporal areas. The component was larger over the right hemisphere consistent with RH dominance in depth processing, likely due to context-dependent top-down modulation. These results demonstrate that the depth illusion obtained from contrast of colour implicates similar cortical areas as classic binocular depth perception.     

2003—2007年郴州市生活饮用水水质监测

目的了解郴州市城区生活饮用水水质，针对存在的问题提出改进建议。方法选取有代表性的城区二次供水、末梢水、出厂水和水源水进行监测，采用国家标准进行评价。结果所监测的二次供水、末梢水、出厂水和水源水的合格率分别为86．3％、84．9％、97．4％和100．0％。不合格的指标分别有游离性余氯、浑浊度、总大肠菌群和细菌总数。结论．郴州市城区生活饮用水水质基本符合国家标准，针对存在的问题，有关部门应加强管理。     

The neural correlates of deficient error awareness in attention-deficit hyperactivity disorder (ADHD)

The ability to detect and correct errors is critical to adaptive control of behaviour and represents a discrete neuropsychological function. A number of studies have highlighted that attention-deficit hyperactivity disorder (ADHD) is associated with abnormalities in behavioural and neural responsiveness to performance errors. One limitation of previous work has been a failure to determine the extent to which these differences are attributable to failures of conscious error awareness, a process that is dependent on the integrity of the frontal lobes. Recent advances in electrophysiological research make it possible to distinguish unconscious and conscious aspects of error processing. This study constitutes an extensive electrophysiological investigation of error awareness and error processing in ADHD. A Go/No-Go response inhibition task specifically designed to assess error awareness was administered to a group of adults diagnosed with ADHD and a group of matched control participants. The ADHD group made significantly more errors than the control group but was less likely to consciously detect these errors. An analysis of event-related potentials elicited by errors indicated that an early performance monitoring component (early positivity) was significantly attenuated in the ADHD group as was a later component that specifically reflects conscious error processing (Pe). Dipole source modelling suggested that abnormal Pe amplitudes were attributable to decreased activation of the anterior cingulate cortex. Decreased electrodermal activity in the ADHD group also suggested a motivational insensitivity to performance errors. Our data provide evidence that neuropsychological deficits associated with ADHD can be exacerbated by error processing abnormalities. Error awareness may represent an important cognitive and physiological phenotype for ADHD.     

Low resolution electromagnetic tomography analysis of ictal EEG patterns in mesial temporal lobe epilepsy with hippocampal sclerosis

ObjectiveTo investigate the difference in the spatial distribution of scalp initial ictal discharge (IID) patterns in mesial temporal lobe epilepsy with hippocampal sclerosis (HS–MTLE).MethodsScalp ictal EEG data in 22 seizure-free patients after temporal lobectomy with amygdalo-hippocampectomy were classified as follows: a regular 5–9 Hz rhythm with a restricted temporal/subtemporal distribution (type 1, 11 patients), or an irregular 2–5 Hz rhythm with a widespread fronto-temporal distribution (type 2, 11 patients). EEG data were fragmented into segments of 1.28 s, both at ictal onset and at baseline. The LORETA solution of three frequency bands was compared between ictal and baseline using statistical non-parametric mapping (p < 0.01).ResultsThe LORETA solution of 5–9 Hz in type 2 had wider cortical activity in the ipsilateral fronto-temporal area, compared to type 1 with activation of the ipsilateral focal mesial and lateral temporal regions. The LORETA solution of 10–13 Hz in both types showed increased activity in the fronto-temporal area, which was wider in type 2 than type 1. Increased cortical activity of <5 Hz was not observed in type 1, whereas increased cortical activity was observed in the bilateral anterior frontal area in type 2.ConclusionsThe cortical source distribution in HS–MTLE may depend on scalp IID frequency. The neural generators of 5–13 Hz may be important for the formation of the ictal onset zone in both ictal patterns.SignificanceSpatial distributions in HS–MTLE patients differ with scalp IID frequency.