全文获取类型
收费全文 | 11269篇 |
免费 | 649篇 |
国内免费 | 111篇 |
专业分类
耳鼻咽喉 | 45篇 |
儿科学 | 374篇 |
妇产科学 | 173篇 |
基础医学 | 369篇 |
口腔科学 | 173篇 |
临床医学 | 1169篇 |
内科学 | 1438篇 |
皮肤病学 | 131篇 |
神经病学 | 322篇 |
特种医学 | 204篇 |
外科学 | 921篇 |
综合类 | 1869篇 |
预防医学 | 2924篇 |
眼科学 | 71篇 |
药学 | 1057篇 |
11篇 | |
中国医学 | 383篇 |
肿瘤学 | 395篇 |
出版年
2024年 | 3篇 |
2023年 | 179篇 |
2022年 | 318篇 |
2021年 | 446篇 |
2020年 | 518篇 |
2019年 | 411篇 |
2018年 | 416篇 |
2017年 | 324篇 |
2016年 | 343篇 |
2015年 | 365篇 |
2014年 | 981篇 |
2013年 | 962篇 |
2012年 | 897篇 |
2011年 | 921篇 |
2010年 | 800篇 |
2009年 | 664篇 |
2008年 | 561篇 |
2007年 | 564篇 |
2006年 | 494篇 |
2005年 | 372篇 |
2004年 | 275篇 |
2003年 | 245篇 |
2002年 | 158篇 |
2001年 | 150篇 |
2000年 | 124篇 |
1999年 | 104篇 |
1998年 | 64篇 |
1997年 | 64篇 |
1996年 | 51篇 |
1995年 | 39篇 |
1994年 | 33篇 |
1993年 | 14篇 |
1992年 | 20篇 |
1991年 | 14篇 |
1990年 | 15篇 |
1989年 | 10篇 |
1988年 | 12篇 |
1987年 | 9篇 |
1986年 | 8篇 |
1985年 | 17篇 |
1984年 | 11篇 |
1983年 | 7篇 |
1982年 | 7篇 |
1981年 | 5篇 |
1980年 | 12篇 |
1979年 | 3篇 |
1978年 | 8篇 |
1977年 | 3篇 |
1973年 | 2篇 |
1972年 | 4篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
41.
Tanya L. Kowalczyk Mullins Caitlyn R. Idoine Gregory D. Zimet Jessica A. Kahn 《The Journal of adolescent health》2019,64(5):581-588
Purpose
Understanding the attitudes of physicians toward the use of pre-exposure prophylaxis (PrEP) for HIV prevention among youth is critical to improving access to PrEP. We examined PrEP-related attitudes among physicians who provide primary care to 13- to 21-year-old adolescents.Methods
Individual, in-depth, semistructured interviews were conducted with 38 physicians from adolescent medicine, family practice, internal medicine/medicine-pediatrics, obstetrics/gynecology, and pediatrics who care for any adolescents younger than 18 years. Interviews assessed familiarity with PrEP, perceived benefits and barriers to providing PrEP to adolescents, facilitating factors for prescribing PrEP, and likelihood of recommending and prescribing PrEP to adolescents.Results
Mean age was 44.6 years (standard deviation 10.9). Fourteen physicians (37%) reported being somewhat or very familiar with PrEP. Perceived benefits of prescribing PrEP included decreased acquisition/rates of HIV, improved provision of sexual health services, and improved patient awareness of HIV risk. Barriers to PrEP were reported at the patient (e.g., lack of acceptability to patients), provider (e.g., concerns about patient adherence, safety/side effects, parents as a barrier to PrEP use), and system (e.g., high cost) levels. Facilitating factors for prescribing PrEP included low cost/coverage by insurance, physician education about PrEP, patient educational materials, and clinical guidelines for PrEP use in youth. A higher proportion of physicians reported being highly or somewhat likely to recommend (N = 16, 42%) than prescribe PrEP (N = 13, 34%).Conclusions
In this study of primary care physician attitudes toward PrEP prescribing for adolescents, physicians identified numerous barriers to providing PrEP. Addressing these barriers may increase adolescents' access to PrEP. 相似文献42.
《Australian critical care》2019,32(6):540-559
ObjectivesThe objective of this review was to describe cardiovascular risk (CVR) assessment methods and to identify evidence-based practice recommendations when dealing with population at risk of developing cardiovascular diseases.Review methods and data sourcesA literature review following the Arksey and O'Malley scoping review methodology was conducted. By using appropriate key terms, literature searches were conducted in PubMed, SciELO, Cochrane Library, Dialnet, ENFISPO, Medigraphic, ScienceDirect, Cuiden, and Lilacs databases. A complementary search on websites related to the area of interest was conducted. Articles published in English or Spanish in peer-review journals between 2010 and 2017. Critical appraisal for methodological quality was conducted. Data was extracted using ad-hoc tables and qualitatively synthesized.ResultsAfter eliminating duplicates, 55 325 records remained, and 1432 records were selected for screening. Out of these, 88 full-text articles were selected for eligibility criteria, and finally, 67 studies were selected for this review, and 25 studies were selected for evidence synthesis. In total, 23 CVR assessment tools have been identified, pioneered by the Framingham study. Qualitative findings were grouped into four thematic areas: assessment tools and scores, CVR indicators, comparative models, and evidence-based recommendations.ConclusionsIt is necessary to adapt the instruments to the epidemiological reality of the population. The most appropriate way to estimate CVR is to choose the assessment tool that best suits individual conditions, accompanied by a comprehensive assessment of the patient. More research is required to determine a single, adequate, and reliable tool. 相似文献
43.
新型冠状病毒病(COVID-19)疫情蔓延期间,防控形势十分严峻,耳鼻咽喉科内镜室作为上呼吸道疾病诊疗的重要场所更需要严加防范。内镜室医务人员处于高风险职业暴露状态,在临床工作中必须按防控方案执行操作。遵照国家卫生健康委对COVID-19防控的总体要求,我科在医院统一部署下,根据耳鼻咽喉科内镜室感控特点,研究分析疫情期间感染危险因素,制定内镜室COVID-19防控方案,以防止医院内交叉感染,保障患者与医务人员安全。 相似文献
44.
45.
46.
47.
48.
《Vaccine》2016,34(26):2921-2925
Human immunodeficiency virus (HIV) is the cause of one of the most lethal pandemics in human history, although in recent years access to highly effective anti-retroviral therapy has provided new hope worldwide. Transmission of HIV by sexual contact, childbirth and injection drug use has been reduced, but 2 million are newly infected each year, and much of the transmission is from people who do not know their status. In addition to known methods, a preventive vaccine is needed to end the pandemic. The extraordinary mutability and genetic diversity of HIV is an enormous challenge, but vaccines are being designed for broad coverage. Computer-aided design of mosaic immunogens, incorporating many epitopes from the entire genome or from conserved regions aim to induce CD8+ T cells to kill virus-infected cells or inhibit virus replication, while trimeric envelope proteins or synthetic mimics aim to induce broadly reactive neutralizing antibodies similar to those cloned from some infected patients. Induction of more potent and durable responses may require new adjuvants or replicating chimeric vectors chimeras that bear HIV genes. Passive or genetic delivery of broadly neutralizing antibodies may provide broad protection and/or lead to insights for vaccine designers. Proof-of-concept trials in non-human primates and in one human efficacy trial have provided scientific clues for a vaccine that could provide broad and durable protection against HIV. The use of vaccines to destroy HIV reservoirs as part of therapy or cure is now also being explored. 相似文献
49.
50.