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31.
硬膜外阻滞麻醉下施行腹部手术,当手术牵拉内脏器官时病人常出现“内脏牵引痛”,为解除这类牵引痛,我院自2002年8月-2004年2月期间对80例硬膜外腔麻醉腹腔手术病人,采用咪唑安定和恩丹西酮做为辅助药,以求解除牵引痛症状,效果尚称满意,今介绍如下。 相似文献
32.
先天性尿道下裂是泌尿外科常见病,男婴中发病率约为0.3%。治疗方法唯有行尿道成形术,矫止阴茎下曲畸形及重建尿道,以满足正常排尿及成年后婚育需求。尿道成形术式多达200余种,各种术式均存在各种各样的并发症,目前仍难以找出一种完美的术式。近3年来我们应用Duckett术一期治疗先天性尿道下裂6例,手术方式相对简单,并发症少,疗效满意,现报告如下。 相似文献
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34.
甲状腺手术引流的改进 总被引:1,自引:0,他引:1
甲状腺手术引流的改进云南省保山地医院外科(678000)张家璋,何联华,杨国富,鲁云我们对于甲状腺术后病人切口下放置胶管,行负压引流袋引流,效果较好。方法:取内径0.6cm或1.0cm乳胶管,长10~20cm,其一尖端剪1~2个侧孔,剪孔按创口大小、... 相似文献
35.
目的:探讨特异性环氧化酶-2(COX-2)抑制剂塞来昔布(celecoxib)对人神经母细胞瘤细胞系SK-N-SH细胞生长的影响及其分子生物学作用机制。方法:不同浓度塞来昔布(12.5、25、50和75μmol/L)用不同时间(24、48和72h)处理SK-N-SH细胞,MTT法检测细胞增殖,DNA ladder法及AO/EB染色法分析细胞凋亡,Western blot检测COX-2、Bcl-2蛋白表达。结果:MTT法显示,12.5、25、50和75μmol/L组在3个时间点对细胞的抑制率分别为(7.38±1.12)%、(10.33±1.97)%和(25.16±5.58)%;(34.46±6.76)%、(30.12±6.71)%和(57.54±3.06)%;(61.85±4.01)%、(50.78±2.85)%和(85.67±2.17)%;(83.85±5.56)%、(90.06±5.71)%和(98.04±4.43)%。组间差异均有统计学意义,P<0.05。结论:塞来昔布抑制SK-N-SH细胞的生长并诱导其凋亡,其机制除了抑制COX-2外还可能与抑制Bcl-2有关,有一定的临床应用价值。 相似文献
36.
Objective To investigate the clinical features and treatment outcomes of different regimens in Chinese patients with lymphoblastic lymphoma(LBL). Methods Forty-three patients with LBL were retrospectively analysed, of which 30 were T-LBL, and 13 B-LBL. Results ①Most patients were young men with a median age of 21, and 63.0% of the T-LBL patients had mediastinal masses. ② Treatment outcome could be assessed in 37 cases, of which the response rate (RR) was 81.1% and complete remission (CR) rate was 67.6%. The RR and CR rates in patients treated with regimens for ALL (ALL-like group) and those treated with regimens for NHL(NHL-like group) were 94.4% , 68.4% and 83.3% , 52.6% , respectively. ③The estimated median overal survival(OS) and progression free survival (PFS) of hematopoietic stem cell transplantation (HSCT) group were significant longer than those of ALL-like group(P =0.018, P=0.025) and NHL-like group(P = 0. 016, P = 0. 011). The OS at 5 years in NHL-like group, ALL-like group and HSCT group were (14.4 ± 9.4) % , (20.2 ± 12.7) % and (79.5 ± 13.1) %, respectively. Conclusion ①LBL is more common in young men, with less involvement of peripheral blood. Compared with B-LBL, T-LBL often has a mediastinal mass and serious cavity effusion. ② Intensive treatment regimens for ALL should be used in LBL. HSCT at CR1 can improve outcome obviously. 相似文献
37.
Objective To investigate the clinical features and treatment outcomes of different regimens in Chinese patients with lymphoblastic lymphoma(LBL). Methods Forty-three patients with LBL were retrospectively analysed, of which 30 were T-LBL, and 13 B-LBL. Results ①Most patients were young men with a median age of 21, and 63.0% of the T-LBL patients had mediastinal masses. ② Treatment outcome could be assessed in 37 cases, of which the response rate (RR) was 81.1% and complete remission (CR) rate was 67.6%. The RR and CR rates in patients treated with regimens for ALL (ALL-like group) and those treated with regimens for NHL(NHL-like group) were 94.4% , 68.4% and 83.3% , 52.6% , respectively. ③The estimated median overal survival(OS) and progression free survival (PFS) of hematopoietic stem cell transplantation (HSCT) group were significant longer than those of ALL-like group(P =0.018, P=0.025) and NHL-like group(P = 0. 016, P = 0. 011). The OS at 5 years in NHL-like group, ALL-like group and HSCT group were (14.4 ± 9.4) % , (20.2 ± 12.7) % and (79.5 ± 13.1) %, respectively. Conclusion ①LBL is more common in young men, with less involvement of peripheral blood. Compared with B-LBL, T-LBL often has a mediastinal mass and serious cavity effusion. ② Intensive treatment regimens for ALL should be used in LBL. HSCT at CR1 can improve outcome obviously. 相似文献
38.
早期霍奇金淋巴瘤不同治疗模式104例回顾性分析 总被引:1,自引:0,他引:1
本研究探讨早期霍奇金淋巴瘤(HL)综合治疗模式与扩大野放疗模式的疗效。回顾性分析解放军307医院1987年1月至2010年12月确诊的104例早期HL患者临床资料,分为综合治疗组76例与扩大野放疗组28例,比较两种治疗模式对疗效、生存状况及不良反应的影响。结果表明,104例早期HL患者中位生存85.42个月,综合治疗组与扩大野放疗组的完全缓解率(72.4%vs 71.4%,P=0.924)、总有效率(97.4%vs 96.4%,P=0.779)、5年总生存率(OS,89.5%vs 89.1%,P=0.528)和8年OS(81.3%vs 70.6%,P=0.528)无统计学差异,但两组的5年无进展生存率(PFS,84.2%vs 69.0%,P=0.040)、8年PFS(80.0%vs 55.5%,P=0.040)和5年复发率(28.1%vs 45.6%,P=0.023)有差异。结论:早期HL的综合治疗模式较扩大野放疗模式可提高PFS及降低复发率,但两组OS未见差异。 相似文献
39.
40.
43例淋巴母细胞淋巴瘤患者临床特点及疗效分析 总被引:1,自引:0,他引:1
Objective To investigate the clinical features and treatment outcomes of different regimens in Chinese patients with lymphoblastic lymphoma(LBL). Methods Forty-three patients with LBL were retrospectively analysed, of which 30 were T-LBL, and 13 B-LBL. Results ①Most patients were young men with a median age of 21, and 63.0% of the T-LBL patients had mediastinal masses. ② Treatment outcome could be assessed in 37 cases, of which the response rate (RR) was 81.1% and complete remission (CR) rate was 67.6%. The RR and CR rates in patients treated with regimens for ALL (ALL-like group) and those treated with regimens for NHL(NHL-like group) were 94.4% , 68.4% and 83.3% , 52.6% , respectively. ③The estimated median overal survival(OS) and progression free survival (PFS) of hematopoietic stem cell transplantation (HSCT) group were significant longer than those of ALL-like group(P =0.018, P=0.025) and NHL-like group(P = 0. 016, P = 0. 011). The OS at 5 years in NHL-like group, ALL-like group and HSCT group were (14.4 ± 9.4) % , (20.2 ± 12.7) % and (79.5 ± 13.1) %, respectively. Conclusion ①LBL is more common in young men, with less involvement of peripheral blood. Compared with B-LBL, T-LBL often has a mediastinal mass and serious cavity effusion. ② Intensive treatment regimens for ALL should be used in LBL. HSCT at CR1 can improve outcome obviously. 相似文献