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61.
Henderson S 《Journal of clinical nursing》2003,12(4):501-508
The Patient's Charter identifies the need for nurses to respect patients' rights to influence their care, and contemporary nursing practice advocates that nurses work in partnership with patients. Hence nurses are encouraged to share their power and facilitate empowerment in their patients by giving them information and support. However, the literature indicates that nurses are not very successful in making patients feel empowered to make informed decisions. This study, conducted in 1998, provides some answers as to why this may be the case. The aim of the study was to explore and describe nurses' and patients' views regarding partnership in care in hospital. Using the grounded theory approach, participants were drawn from four hospitals in Western Australia. A purposive sample of 33 nurses and 32 patients were interviewed in-depth. Participant observation was also conducted and field notes were written. The interviews were transcribed verbatim and analysed using the constant comparative method. The findings showed that nurses viewed involving patients in care as requiring them to give patients information and to share their decision-making powers with them. With the exception of a few, the majority of nurses were unwilling to share their decision-making powers. This created a situation of power imbalance with subsequent little patient input. Factors identified included nurses' beliefs that they "know best", the view that patients lacked medical knowledge and the perceived need for nurses to hold onto their power and maintain control. If nurses and patients are to work as partners, it is important that nurses make every effort to equalize the power imbalance. One way to do this is for nurses to share and give information to patients readily and to be open in their communication with them. 相似文献
62.
Psychosocial work characteristics and self rated health in four post-communist countries 总被引:10,自引:1,他引:9 下载免费PDF全文
Pikhart H Bobak M Siegrist J Pajak A Rywik S Kyshegyi J Gostautas A Skodova Z Marmot M 《Journal of epidemiology and community health》2001,55(9):624-630
STUDY OBJECTIVES: To examine whether psychosocial factors at work are related to self rated health in post-communist countries. DESIGN AND SETTINGS: Random samples of men and women in five communities in four countries were sent a postal questionnaire (Poland, Czech Republic and Lithuania) or were invited to an interview (Hungary). Working subjects (n=3941) reported their self rated health in the past 12 months (5 point scale), their socioeconomic circumstances, perceived control over life, and the following aspects of the psychosocial work environment: job control, job demand, job variety, social support, and effort and reward at work (to calculate a ratio of effort/reward imbalance). As the results did not differ by country, pooled analyses were performed. Odds ratios of poor or very poor health ("poor health") were estimated for a 1 SD increase in the scores of work related factors. MAIN RESULTS: The overall prevalence of poor health was 6% in men and 7% in women. After controlling for age, sex and community, all work related factors were associated with poor health (p<0.05). After further adjustment for perceived control, only two work related factors remained associated with poor health; the odds ratios (95% confidence intervals) for 1 SD increase in the effort/reward ratio (log transformed) and job variety were 1.51 (1.29, 1.78) and 0.82 (0.73, 1.00), respectively. Further adjustment for all work related factors did not change these estimates. There were no interactions between individual work related factors, but the effects of job control and social support at work differed by marital status, and the odds ratio of job demand increased with increasing education. CONCLUSIONS: The continuous measure of effort/reward imbalance at work was a powerful determinant of self rated health in these post-communist populations. Although the cross sectional design does not allow firm conclusions as to causality, this study suggests that the effect of the psychosocial work environment is not confined to Western populations. 相似文献
63.
The investigation of chromosomal aberrations in adrenocortical tumours has been limited by the difficulties of applying classical cytogenetics to tumours with low levels of proliferation. We have therefore applied the technique of interphase cytogenetics to paraffin-embedded archival specimens of 14 adrenocortical adenomas and 13 carcinomas. Hybridizations were performed using centromere-specific probes to chromosomes 3, 4, 9, 17, 18 and X, which have been shown to be altered in other types of tumours. Chromosomal imbalance was defined on the basis of changes in both chromosome index (CI) and signal distribution (SD). Where only one of these was altered, this was classified as a tendency to gain or loss. On the basis of the analysis of optimal hybridizations, carcinomas showed gains in all chromosomes studied, five of nine showing gains in multiple chromosomes. Gains were most common in chromosomes 3, 9 and, in particular X, eight of 11 showing gain, and one a tendency to gain. Chromosomal gain was seen less commonly in adenomas, but again chromosomes 3, 9 and X were involved. Losses were infrequent, only one carcinoma showing loss of chromosome 18, and adenomas showing a tendency to loss of chromosomes 4 (two cases), 17 (one case) and 18 (two cases). Our data suggest that changes in chromosomes 3, 9 and X are early events in adrenocortical tumorigenesis, and that there is increasing chromosomal instability with tumour progression. 相似文献
64.
65.
High intra-population genetic diversity and multiple measures of genetic variability at STR loci are useful in inferring past evolutionary history. However, STRs, categorized by their repeat motif size, differ in a number of aspects, requiring separate analyses. We analyzed 783 STRs in 36 worldwide populations to examine marker suitability as well as correlations between various measurements, to evaluate the extent of genomic diversity present in modern human populations. The loci were grouped by type and analyzed separately for each population group. Genetic variation defined by gene diversity and allele size variance, shows different trends of variation across four types of STRs. Additionally, there is little variation of genetic diversity, but there is decreased allelic size variance with increasing repeat motifs. A poor correlation between genetic diversity and allelic size variance across loci in all groups for Di-STRs is probably caused by the presence of allelic size gaps. In contrast, allelic size variance, genetic diversity, and number of alleles are strongly correlated with both tri- and tetra-STRs. The positive correlation of allelic size variance and presence of gaps within the range of allelic sizes in Di-STRs alone explains these observations. An unexpected high imbalance index (β) at Di-STRs due to high allelic size variance also supports this assertion. 相似文献
66.
Dr. Giorgio Coccagna Alessandro Capucci Simone Pierpaoli 《Clinical autonomic research》1999,9(3):135-138
A young man presented with tachycardia and faintness after an episode of influenza. He underwent 24-h heart rate recordings, each of which documented episodes of sinus arrest lasting up to 7.2 seconds. All episodes occurred in the second half of the night and were always accompanied by severe bradycardia. Cardiac function tests failed to disclose anything abnormal. Two polysomnographic recordings demonstrated that the sinus arrests occurred during REM sleep. Power spectral analysis of heart rate variability showed that during the second half of the night there was an abnormal prevalence of vagal activity, particularly during REM sleep stages, presumably responsible for the bradycardia and fall in blood pressure. We speculate that the episodes of sinus arrest are linked to a central mechanism that triggers the autonomic imbalance during REM sleep. 相似文献
67.
抗生素相关性肠道菌群失调的现状调查 总被引:1,自引:0,他引:1
目的 :了解我院菌群失调与抗生素应用情况 ,以增强医护人员合理使用抗生素意识。方法 :采用粪便直接涂片染色法诊断有无菌群失调及菌群失调的程度 ,并采用前瞻性和回顾性相结合的方法 ,调查抗生素应用情况。结果 :老年患者发病率较高 ,抗生素相关性菌群失调的发病率为 6 5 .0 % ,引起菌群失调的药物种类多样化 ,主要是头孢菌素、亚胺培南、青霉素、哌拉西林、克林霉素。结论 :对特殊人群使用抗生素时 ,有必要进行肠道菌群的监测 ,以促进抗生素的合理应用。 相似文献
68.
69.
V. I. Petukhov L. Kh. Baumane I. Ya. Kalvinsh A. P. Skesters A. A. Silova B. Rozentale L. A. Ivanchenko 《Bulletin of experimental biology and medicine》2008,146(6):875-877
Measurements of nitrogen oxide and copper in the blood of 57 patients with chronic viral hepatitis C was carried out before
antiviral therapy by electron paramagnetic resonance on a Radiopan EPR spectrometer. The results indicate elevated levels
of nitrogen oxide and copper in the blood of these patients in comparison with normal subjects. Comparison of these findings
with the results of a previous analysis of redox status of patients with chronic viral hepatitis C indicate that this disease
is characterized by a significant pro-oxidant shift in the realization of redox processes and disorders in the metal ligand
homeostasis (at least as regards copper).
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 146, No. 12, pp. 704–706, December, 2008 相似文献
70.
肺心病人临终前酸碱失衡及死亡原因的探讨 总被引:1,自引:1,他引:0
本文分析了179例肺心病人临终前动脉血气、血电解质和死亡原因。结果表明:肺心病人在临终前的酸碱失衡是常见的。其中慢性呼吸性酸中毒最常见,其它依次为三重酸碱失衡、慢性呼吸性酸中毒并代谢性酸中毒和慢性呼吸性酸中毒并代谢性碱中毒。慢性呼吸性碱中毒、慢性呼吸性碱中毒并代谢性碱中毒和代谢性酸中毒是少见的。肺心病人死亡的主要原因是并发上消化道出血,其次为直接死于酸碱失衡,特别是三重酸碱失衡。 相似文献