异氟醚对缺氧心肌细胞的影响

目的 :探讨异氟醚对心肌细胞缺氧损伤的影响。方法 :将原代培养成活 48h的大鼠乳鼠心肌细胞分为 3组 :A组为对照组 (氰化钠造成心肌细胞细胞内缺氧模型 ) ,B组为 Iso1组 (缺氧 +0 .2 8mm ol/L异氟醚 ) ,C组为 Iso2组(缺氧 +2 .8m mol/L异氟醚 )。比较 3组心肌细胞细胞形态学 (倒置相差显微镜、透射电镜观察 )的变化及 A值的改变。结果 :缺氧 12 h后 ,对照组细胞搏动功能变化明显 ,呈散在细胞搏动 ,而实验组搏动频率减慢。随着时间的延长 ,细胞形态学变化逐渐明显 ,对照组较实验组变化更显著。结论 :异氟醚对培养心肌细胞缺氧损伤有一定的保护作用。     

影响玉米秸秆微生物降解制肥的因素浅析

试验以粉碎后的玉米秸杆为原料进行好氧微生物降解制造有机肥，通过比较不同含水率和通气条件对秸秆降解效率的影响，以及降解过程中温度，pH，微生物量的变化，总结出微生物降解玉米秸秆过程的变化规律。由试验可知，水分与通气条件均是影响发酵效果的重要因素，且制造堆肥的最佳含水率在60％－70％。     

热舒适的生理机制及其与健康的关系

基于生理学、心理学的角度分析了热舒适产生的过程，探讨了热舒适、健康以及与环境之间的关系，指出稳态、舒适的环境不一定有利于健康，它减弱了人适应环境的能力。人同时交替在室内室外两种差异较大的环境中生活时，可能会给人的生理心理及适应能力带来影响。     

紫杉醇加顺铂同步放疗治疗晚期非小细胞肺癌的近期疗效

目的　探讨低剂量紫杉醇加顺铂同步放疗对晚期非小细胞肺癌 (NSCLC)治疗价值。方法　将 40例晚期NSCLC病人随机分成 2组。放化疗同步组 (RT +CT组 ) :紫杉醇 ( 3 0～ 40mg m2 )加顺铂( 4 0mg m2 )每周应用 ,化疗 4周期。同步胸部放射治疗 60～ 70Gy(常规分割 )。单纯化疗组 (CT组 ) :应用紫杉醇 ( 13 0mg m2 )加顺铂 ( 70～ 80mg m2 ) ,化疗 2周期以上。结果　RT +CT组总有效率 66.7% ,CT组为 3 1.8% (P <0 .0 5 )。RT +CT组主要副作用为放射性食管炎和放射性肺炎 ,骨髓抑制低于CT组 ,CT组主要副作用为血液毒性。结论　低剂量紫杉醇加顺铂方案同步放疗近期有效率高 ,毒副作用可以耐受 ,优于单纯化疗组。     

In vivo mechanical condition plays an important role for appearance of cartilage tissue in ES cell transplanted joint

The objective of this study was to evaluate the effects of the mechanical environment on the formation of cartilage tissue in transplanted embryonic stem (ES) cells. Full‐thickness osteochondral defects were created on the patella groove of SD rats, and ES cells (CCE ES cells obtained from 129/Sv/Ev mice and Green ES FM260 ES cells obtained from 129SV [D3] ‐ Tg [NCAG‐EGFP] CZ—001–FM260Osb mice) were transplanted into the defects embedded in collagen gel. The animals were randomly divided into either the joint‐free group (JF group) or the joint‐immobilized group (JI group) for 3 weeks after a week postoperatively. The results showed that cartilage‐like tissue formed in the defects of the JF group whereas large teratomatous masses developed in the defects of the JI group. Some parts of the cartilage‐like tissue and the teratomatous masses were positively stained with immunostain for GFP when the Green ES FM260 ES cells were transplanted. It is suggested that the environment plays an important role for ES cells in the process of repairing cartilage tissue in vivo. © 2007 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 26:10–17, 2008     

Le rôle du soutien social dans la prédiction de la violence chez les personnes atteintes de troubles mentaux graves

The evaluation of the risk of violent behavior in severely mentally ill rests on clinical and contextual factors, such as the presence of a co-diagnosis of alcohol or drug abuse, the presence of antisocial personality disorder, the quality of interpersonal relationships and the social support. There are several definitions of social support, therefore several measurements. Nevertheless, the link between the social support and physical and mental health are shown in the literature. Social support can be beneficial or a source of stress; consequently, it is considered a contextual risk factor for violence, or a protection factor, for individuals suffering with severe mental illness. Few studies consider the possible conflicting aspect of social support and even less show the relationship between social support and violence using non-linear analyses. This type of analysis would allow obtaining profiles likely to better explain the functioning of individuals in the context of the relationship between social support and violence, with the aim of intervening in a precise, personalized and targeted way, while decreasing the risk of violence in severely mentally ill.     

Vaccination coverage against 2009 seasonal influenza in chronically ill children and adults: Analysis of population registries in primary care in Madrid (Spain)

Using electronic clinical records in primary care (ECRPC) of the entire population living in the Autonomous Community of Madrid, Spain (5,102,568 persons) as a data source, this study aimed to ascertain seasonal anti-influenza vaccination coverage in the chronically ill at-risk children (aged 6 months to14 years) and adults (15–59 years).     

危重症临床监护信息系统的应用特点和支撑条件

危重症临床监护信息系统能自动采集监护仪上的生命体征，确认和转换医嘱，准确记录患者的出入量，预先做好模板方便病情描述，查询病历资料，实现病历电子化存储。系统监护仪要有数据输出接口，系统和医院信息无缝连接．系统的整体结构布局。     

Fast,exact k‐space sample density compensation for trajectories composed of rotationally symmetric segments,and the SNR‐optimized image reconstruction from non‐Cartesian samples

A recently developed method for exact density compensation of non uniformly arranged samples relies on the analytically known cross‐correlations of Fourier basis functions corresponding to the traced k‐space trajectory. This method produces a linear system whose solution represents compensated samples that normalize the contribution of each independent element of information that can be expressed by the underlying trajectory. Unfortunately, linear system‐based density compensation approaches quickly become computationally demanding with increasing number of samples (i.e., image resolution). Here, it is shown that when a trajectory is composed of rotationally symmetric interleaves, such as spiral and PROPELLER trajectories, this cross‐correlations method leads to a highly simplified system of equations. Specifically, it is shown that the system matrix is circulant block‐Toeplitz so that the linear system is easily block‐diagonalized. The method is described and demonstrated for 32‐way interleaved spiral trajectories designed for 256 image matrices; samples are compensated non iteratively in a few seconds by solving the small independent block‐diagonalized linear systems in parallel. Because the method is exact and considers all the interactions between all acquired samples, up to a 10% reduction in reconstruction error concurrently with an up to 30% increase in signal to noise ratio are achieved compared to standard density compensation methods. Magn Reson Med 60:339–349, 2008. © 2008 Wiley‐Liss, Inc.     

类风湿性关节炎病人的心理健康状况及相关因素

类风湿性关节炎病人的心理健康问题主要表现为严重的焦虑和抑郁症状、抑郁症。影响他们心理健康的因素涉及疼痛、社会支持、自我尊重与对疾病的调理能力、大脑功能等因素。针对性的心理健康促进措施主要有认知-行为干预、心理教育干预,这些干预措施在不同程度上改善了类风湿性关节炎病人的心理健康状况。