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61.
目的观察耳廓复合游离组织瓣连续法修复鼻翼缺损的疗效,以探讨鼻翼缺损的有效修复手段。方法耳廓复合游离组织瓣2次连续法修复鼻翼缺损7例,移植物面积0.5cm×0.7cm~0.8cm×1.2cm。结果7例耳廓复合游离组织瓣移植后全部成活。术后随访6~18个月,移植物无明显回缩,鼻外形满意。结论耳廓复合游离组织瓣连续移植修复鼻翼缺损,适合较严重鼻翼缺损,手术成功率高,术后鼻外形满意,双侧分次取材,耳廓外形双侧对称无畸形。 相似文献
62.
目的 探讨鼻窦CT扫描在内窥镜鼻窦手术中的应用价值。方法 回顾性对80例慢性鼻窦炎患者鼻窦CT扫描与手术中所见进行分析总结。结果 冠状位CT扫描鼻窦病变发现率高,辅以水平CT扫描,鼻窦精细结构、病变范围和程度能够清楚地显示,符合术中所见。结论 鼻窦CT扫描能精确显示鼻窦结构及病变,能正确指导鼻窦内窥镜手术。 相似文献
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Petra M.C. Callenbach Lise P.M. Pels Paul G.H. Mulder Wim H.J.P. Linssen Rob H.J.M. Gooskens Jan L. van der Zwan Oebele F. Brouwer For the SUM Trial Group 《European journal of paediatric neurology》2007,11(6):325-330
About 4-10% of children and adolescents suffer from migraine. In the last few years, several studies have been performed to assess the efficacy and safety of triptans for the acute treatment of migraine in children and adolescents. Only sumatriptan nasal spray has been approved for the treatment of acute migraine with or without aura in adolescents aged 12-17 years in Europe. This review describes the results of the studies with sumatriptan nasal spray that have been performed in children and adolescents, including a study performed in the Netherlands. 相似文献
65.
Background Prosia gland in D2 (PGD2) is a very important mast cell product during the early-phase nasal allergic reaction. However, the quantification of PGD2 in nasal secretions has not yet been well established. Objective Quantitative determination of PGD2 in nasal secretions of atopic patients (n=17) after nasal allergen challenge (NAC) and in non-allergic healthy volunteers (n=10). Methods The nasal microsuction sampling technique was used to obtain the nasal secretions with an exactly known and minimally diluted volume. A sensitive and specific enzyme immunoassay was chosen to measure the more stable 11-methoxime derivative of PGD2. which was obtained after extraction in acelone/ethanol and conversion using methoxamine-HCl. The concentrations of PGD2 in nasal secretions obtained from 10 non-allergic healthy volunteers were used as reference values. Results There was no significant difference in the concentrations of PGD2 between men (median: 569pg/mL) and women (median: 407pg/mL), nor between the baseline concentrations from atopic patients (median: 410pg/mL) and non-allergic controls (median: 477 pg/mL). In the atopic patient group, PGD2 did not significantly increase during the entire sampling period after NAC. The absence of PGD2 response contrasted with the nasal symptoms manifested by sneezing, increased nasal airway resistance, and the significant increases of the concentrations of histamine, tryptase, and leukotriene C4 (LTC4) 5min after NAC. Conclusion This observation suggests that the measurement of PGD2 alone in the nasal secretions does not give reliable information on mast cell activation during a nasal allergic reaction. 相似文献
66.
The local mean and the average difference of four pairs of test locations within the 26° visual field, situated above and below the horizontal nasal meridian, were used to predict the global field indices MD and CLV of the Gl glaucoma program. Out of 539 examinations (194 eyes suspected of having glaucoma), the local indices NDIFF (describing asymmetrical behavior around the nasal horizontal meridian), ND0 (the mean defect in the nasal region), and the global indices MD and CLV were calculated. Seven hundred fifty-five examinations (446 normal eyes) served as a control group. First and second examinations of 146 glaucoma suspect eyes were used to calculate the retest reliability scores for the indices in question. When analyzing the glaucoma suspects, the local index NDIFF, together with the local mean defect, ND0, yielded highly reliable estimates of the global indices MD and CLV, with a retest correlation r = 0.86 for NDIFF, and r = 0.96 for ND0. The covariance of NDIFF with CLV was r = 0.67, while the co-variance of MD with ND0 was r = 0.95.The ranges of the local indices ND0 and NDIFF were each classified into normal range and range of suspected pathology, in analogy to the normal and pathological ranges of the global field indices. Equivalence of the local indices with the corresponding ranges of MD and CLV was investigated and the results are shown. The establishment of local indices may prove to be a powerful tool in early detection of glaucomatous damage. 相似文献
67.
Rhinosinusitis is diagnosed frequently in clinical practice, but the term may in fact encompass a wide spectrum of diseases.
Inflammation of the nasal and sinus mucosa can arise from various causes and lead to different sequelae. Moreover, the term
rhinosinusitis is more accurate than sinusitis. Causes range from a viral infection leading to the common cold to an invasive,
fungal infection. An accurate diagnosis is important because effective therapy is available if recognized early and if specific
therapy is used. Importantly, there is a close relationship between upper and lower airway disease and each have unique structural
and functional differences that make an understanding of rhinosinusitis important not only for upper airway disease, but also
for the management of asthma. All too often, rhinosinusitis becomes chronic and this becomes a challenge because medical therapy
may not be sufficient to control disease. Finally, we should note that the differential diagnosis of rhinosinusitis is extensive
and physicians should place heavy emphasis not only on the history, but also on appropriate imaging studies. A normal exam
does not rule out the possibility or rhinosinusitis. Finally, we should emphasize that effective treatment is dependent on
the etiology of the symptoms but also dependent on whether it is acute or chronic. 相似文献
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