活血通降方对瘀血阻络证反流性食管炎患者胃电图的影响

目的:观察活血通降方治疗瘀血阻络证反流性食管炎(RE)对胃电图的影响,从电生理角度探讨该方药的作用机制。方法:筛选瘀血阻络证RE患者60例,随机分为两组予以治疗,西药组30例:奥美拉唑+多潘立酮+铝碳酸镁,中西药组30例:奥美拉唑+活血通降方,对患者治疗前及治疗后4周及8周后症状学积分、胃镜表现及胃电图进行比较分析。结果:西药组:西医症状学积分:治疗前(20.59±4.25)分,治疗4周(16.21±3.02)分,治疗8周(9.32±2.08)分,差异有统计学意义(P 0.05);中医症状学积分:治疗前(43.28±8.09)分,治疗4周(35.06±5.03)分,治疗8周(18.23±4.09)分,差异有统计学意义(P 0.05);胃镜分级:治疗前A级8例,B级16例,C级6例,治疗8周后14例恢复正常,A级10例,B级5例,C级1例;中西药组:西医症状学积分:治疗前(19.38±3.05)分,治疗4周(15.23±2.12分),治疗8周(7.23±3.12)分,差异有统计学意义;中医症状学积分:治疗前(45.41±7.12)分,治疗4周(35.34±4.11)分,治疗8周(15.12±5.21)分,差异有统计学意义(P 0.05);胃镜分级:治疗前A级7例,B级15例,C级8例,治疗8周后16例恢复正常,A级9例,B级5例,C级0例;与西药组比较,中西药组治疗后症状学及内镜改善更明显,胃电图主要表现为主频下降,慢波百分比区趋于正常,胃动过速、胃动过缓及节律紊乱百分比减低。结论:活血通降方可缓解瘀血阻络证RE患者临床症状及情志,改善胃镜下黏膜表现,具有黏膜保护、动力调节的作用,其机制可能是通过调节胃食管肌电活动及电节律紊乱而发挥作用的。     

脑卒中急性期空腹胃电图动态变化分析

目的 观察脑卒中患者急性期空腹胃电图参数的动态变化,并探讨其相关发生机制.方法 应用体表胃电图检测127例急性脑卒中患者入院24 h及入院1周时空腹胃电参数变化,并与34名健康对照组相对比.结果 与正常组相比,脑卒中患者入院24 h胃窦及胃体部胃电振幅明显降低,入院1周时两部位胃电振幅则升高接近正常水平.胃窦及胃体部两不同时间的胃电频率与正常组相比无统计学意义.同时,脑出血患者入院24 h胃窦及胃体部的胃电振幅与正常组相比均明显降低(P<0.05),入院1周时已升高至正常水平.而脑梗死患者胃窦及胃体部两不同时间胃电振幅与正常组相比均无统计学意义.结论 脑卒中患者急性期胃窦、胃体部的蠕动频率未见明显改变,而胃窦、胃体部的蠕动强度受到抑制,且不同性质的脑卒中类型对胃动力的影响亦不相同,其中脑出血患者胃窦、胃体部的蠕动强度降低尤为明显.     

不同亚型胃食管反流病患者胃动力检测的研究

目的:采用生物阻抗胃动力检测系统和评价方法研究不同亚型胃食管反流病(Gastroesophageal refluxdisease,GERD)患者胃动力情况.方法:选取103例GERD患者,行GERD的反流症状(Gastroeso phageal reflux disease,GerdQ)评分,并通过胃动力检测系统提取胃...     

Increased feelings with increased body signals

Since the beginning of psychology as a scientific endeavour,the question of whether the body plays a role in how a personexperiences emotion has been the centre of emotion research.Patients with structural gastrointestinal disorders, such asCrohn's disease, provide an intriguing opportunity to studythe influence of body signals on emotions and feelings. In thepresent study, emotionally salient films were presented to participantswith Crohn's disease in either the active state (Crohn's-active,CA) or silent state (Crohn's-silent, CS), and to normal comparison(NC) participants. We hypothesized that CA participants wouldhave increased feelings, compared with CS and NC participants,when viewing emotional films designed to elicit happiness, disgust,sadness and fear. Gastric myoelectrical activity (electrogastrogram,or EGG) was measured during the films, and after each film waspresented, participants rated emotion intensity (arousal) andpleasantness (valence). All groups labelled the emotions similarly.In support of the hypothesis, CA participants showed an increasein subjective arousal for negative emotions compared with CSand NC participants. The CA participants also showed increasedEGG during emotional film viewing, as well as a strong positivecorrelation of EGG with arousal ratings. Together, these findingscan be taken as evidence that aberrant feedback from the gastrointestinalsystem up-regulates the intensity of feelings of negative emotions.     

前庭刺激对飞行人员胃电图影响的研究

为探讨应用胃电图定量描述前庭刺激对植物神经功能的影响，用运行谱和相对 值对８１我飞行人员前庭刺激前，中，后的胃电图进行了分析，结果表明，前庭刺激可使胃电图的主幅不稳定率，主频不稳定率和胃动过缓，正常节律，胃运过速的发生率产生不同程度的改变。     

视动错觉诱发的运动病动态发生过程与胃电的联系

目的 在视动刺激诱发运动病过程中，探讨胃电的变化与运动病恶心症状动态发生过程的联系，为运动病的预测和防护提供思路和依据。方法 20名18－25岁的健康男性，分别接受15min的单纯视动刺激实验，记录了运动病症状并采集了胃电信号。结果 （1）11名恶心发生者运动病分值明显高于9名恶心未发生者（P＜0．001）；同时，恶心发生者胃节律过速百分比的增加和主导慢波百分比的减少都明显大于9名恶心未发生者胃电两参数的变化（都为P＜0．001）；（2）11名恶心发生者自身旋转错觉出现的时间明显早于胃电的变化（P＜0．001）；（3）刺激过程中，11名恶心发生者胃电主导慢波（Primary Wave,Pw)和胃节律过速（Tachygastria,Tach)百分比减低或增加都明显早于恶心症状的发生（都为P＜0．01）。结论 （1）恶心时胃电的变化程度明显高于未恶心时；（2）自身旋转错觉与胃电的变化和恶心的发生有密切的关系；（3）胃电的变化先于恶心症状的出现。     

体表胃电图慢波提取方法的比较研究

体表胃电图(electrogastrogram,EGG)具有幅值小、频率低和窄带宽的特点,并且极易受到心电、呼吸以及运动等干扰.文中对三种常用的EGG慢波的提取方法进行了比较,包括自适应滤波、小波多尺度分解和经验模态分解,并将三种方法分别应用于模拟的含噪EGG信号以及临床EGG慢波的提取.研究结果表明,三种方法各有优缺点,均能有效地提取出EGG信号中的慢波成分.与自适应滤波相比,小波多分辨率分解和经验模态分解获得了更高的信噪比和更低的重构方差.     

功能性消化不良中医证型与胃电图的关系探讨

临床上笔者根据功能性消化不良所具有的证候特征,分为三型:即脾胃虚弱型、肝气犯胃型及肝郁胃热型。其中脾胃虚弱型与肝气犯胃型类似于运动障碍型,而肝郁胃热型类似于溃疡样型。本文对120例功能性消化不良中医证型与胃电图之间的关系进行分析,发现脾胃虚弱型组胃电幅值比正常组及肝郁胃热型组低,肝气犯胃型组胃电幅值则呈不规则变化,肝郁胃热型组胃电幅值比正常人组高(P<0.05)。胃电波幅在一定程度上反映了中医脾、胃、肝的病理生理变化。胃电图对功能性消化不良的中医证型提供了一定的诊断依据。     

Electrogastrography Differentiates Reflux Disease With or Without Dyspeptic Symptoms

Many patients with gastroesophgeal reflux disease (GERD) may also have overlapping symptoms of dyspepsia. This study was to examine if GERD patients could be separated into meaningful groups based on their gastric myoelectrical characteristics. The study included 20 GERD patients with dyspeptc symptoms (GERD+) and 17 patients with GERD. Gastric myoelectrical activity was assessed using cutaneous electrodes to record electrogastrograms (EGGs). The GERD+ patients ingested smaller volumes of water compared to patients with GERD (P < 0.05). At baseline, the percentage of gastric myoelectrical power in the normal 3-cpm range was significantly less in patients with GERD+ compared with the GERD subjects (P = 0.01). Power in the bradygastria range was significantly greater in patients with GERD+ (P = 0.005). The GERD+ group had a significant increase in the percentage of power in the tachygastria range later after ingesting the water load (P < 0.01). In conclusion, this study has shown that more gastric dysrhythmias were detected in the GERD+ patients accompanied with altered perception of stomach fullness.     

胃必欢颗粒治疗功能性消化不良的临床研究

[目的]观察胃必欢颗粒治疗功能性消化不良(FD)患者的疗效。[方法]将142例FD患者随机分为胃必欢颗粒治疗组(72例),多潘立酮对照组(70例),观察两组治疗前后临床症状、胃排空、胃电图的变化。[结果]治疗组和对照组总有效率分别为90.27%和85.71%(P<0.05)。胃必欢颗粒能有效改善症状,促进胃排空,改善胃电节律紊乱,与对照组比较P<0.05。[结论]胃必欢颗粒具有多途径改善FD患者的胃动力作用。