悬灸早期介入对急性面瘫血清炎性因子的影响

目的：探究悬灸早期介入对急性期面瘫（BP）的抗炎效果，为悬灸急性期介入治疗面瘫提供理论依据。方法：选取2016年3月至2019年3月成都中医药大学附属医院收治的BP患者132例作为研究对象，按照治疗方法的不同分为悬灸组（n=38）、激素组（n=46）和悬灸加激素组（n=48）；同时随机抽取体检中心体检结果无特殊异常者作为正常人群（n=126）。将正常人群同急性期BP患者相关血清炎性因子比较，观察BP患者血清炎性因子有无改变；采用随机对照研究，将急性期BP患者132例分为悬灸组、激素组、悬灸加激素组，均治疗2周，比较患者治疗前后血清炎性因子水平，并同时采用House-Brackmann（H-B）整体评分量表进行疗效评价，观察组间差异。结果：与正常人群比较，急性期BP患者血清相关炎性因子均呈升高趋势，组间比较差异有统计学意义（P<0.05）；治疗2周后，3组BP患者血清WBC、NEUT、PLT、TNF、NLR和H-B整体评分与治疗前比较，差异均有统计学意义（P<0.05）；治疗后3组间比较，WBC、NEUT、LC差异有统计学意义（P<0.05），其他指标和H-B整体评分3组间比较，差异无统计学意义（P>0.05）。结论：和正常人比较，急性期BP患者血清相关炎性因子呈增高趋势；3种方法均能在一定程度上降低急性期BP患者相关血清炎性因子水平，3种方法疗效差异无统计学意义，悬灸可作为激素的一种替代和补充。     

Three-dimensional soft tissue changes after reduction malarplasty in female patients

The aim of this study was to determine the three-dimensional soft tissue changes after reduction malarplasty. Soft tissue changes relative to the amount of movement of the zygomatic bone were studied. Pre- and postoperative cone beam computed tomography images of 21 female patients were superimposed. The anterior-most point of the body osteotomy (point A), arch osteotomy site (point D), and points dividing line A–D into thirds (points B and C) were marked on lateral view images. The vertical distances from the midsagittal line to the centre of the zygomatic bone and the outer prominence of the soft tissue were measured on the coronal view of each image. The proportion of the change in soft tissue to that of the bone before and after surgery was calculated for each point. The relationship between body mass index and the soft tissue change ratio, and the differences in soft tissue changes at each point were analysed. Mean soft tissue changes for points A, B, C, and D were 53.43%, 66.66%, 63.67%, and 57.23%, respectively. The amount of soft tissue change at point B was greater than that at points A and D, which were osteotomy sites. There was no statistical correlation between body mass index and the soft tissue change ratio at each point.