Understanding the relationship between co-occurring PTSD and MDD: symptom severity and affect

How to best understand theoretically the nature of the relationship between co-occurring PTSD and MDD (PTSD + MDD) is unclear. In a sample of 173 individuals with chronic PTSD, we examined whether the data were more consistent with current co-occurring MDD as a separate construct or as a marker of posttraumatic stress severity, and whether the relationship between PTSD and MDD is a function of shared symptom clusters and affect components. Results showed that the more severe depressive symptoms found in PTSD + MDD as compared to PTSD remained after controlling for PTSD symptom severity. Additionally, depressive symptom severity significantly predicted co-occurring MDD even when controlling for PTSD severity. In comparison to PTSD, PTSD + MDD had elevated dysphoria and re-experiencing – but not avoidance and hyperarousal – PTSD symptom cluster scores, higher levels of negative affect, and lower levels of positive affect. These findings provide support for PTSD and MDD as two distinct constructs with overlapping distress components.     

新世纪国际人工智能研究领域可视化分析

目的:全面了解新世纪国际人工智能领域的研究现状与研究热点。方法:运用TDA软件,利用文献统计分析、关键词共现分析的方法揭示研究热点。结果:国际人工智能领域文献量呈上升趋势,其中美国发文量排名第一,中国位居第六。人工智能的主要研究领域包括计算机科学、工程学、自动化与控制系统3个学科。研究热点为遗传算法、神经网络和机器学习。结论:新世纪国际人工智能研究涉及多个学科,研究热点集中在知识获取、知识表示和问题求解3个宏观层面,神经网络、遗传算法和机器学习是研究者们关注的核心。     

基于文献挖掘视角的组学研究脉络梳理

目的：梳理组学研究脉络,分析组学研究热点趋势,帮助科研工作者把握研究方向,为科研管理部门在组学研究方面的资助提供决策支持。方法：利用E-utilities下载1986-2016年PubMed数据库收录的含有“-Omics/Omic/Omes/Ome”的题录信息27 040 819条,在题录信息的题目和摘要中对以“-Omics/Omic/Omes/Ome”结尾的词进行标注、筛选,并利用词频分析法、共现分析法、社会网络分析法对筛选结果进行分析。结果：获得组学相关记录共346 977条,文献发表量逐年递增,自2000年后呈井喷式增长。各类单一组学的文献发表量均呈逐年递增的趋势,其中基因组学文献发表量最多。2014年之后,转录组学的文献发表量赶超了蛋白质组学,成为继基因组学之后的第二大组学类型。转录组学、线粒体基因组学与基因组学共现的文献量在某一时间节点后呈井喷式增长,其余组学类型与基因组学共现的文献量都稳定增长。结论：后基因组时代把组学研究推向了高潮,无论是数量还是种类都出现了井喷式的增长。多类型组学的融合研究越来越受科研人员的关注。     

Alcohol misuse in bipolar disorder. A systematic review and meta-analysis of comorbidity rates

AimsTo assess the comorbidity rates of alcohol use disorders (AUDs) in bipolar disorder (BD) and to explore possible sources of heterogeneity.MethodsStudies were identified through database searches. Meta-analytic techniques were employed to aggregate data on lifetime comorbidity and to explore possible sources of heterogeneity. Funnel plots were used to detect publication bias.ResultsIn clinical studies, AUDs affected more than one in three subjects with BD. Significant heterogeneity was found, which was largely explained by the geographical location of study populations and gender ratio of participants. AUDs affected more than one in five women and two in five men.ConclusionAUDs are highly prevalent in BD. Our study revealed a substantial heterogeneity across studies. Further research including control groups is needed. Patients with BD should be assessed for current and previous AUDs.     

基于共词分析的军队医院SCI论文热点分析

基于关键词共现分析,利用SPSS软件的聚类和多维尺度分析军队137家医院2006-2013年发表的SCI论文研究方向及其随时间的变化。指出军队医院近8年内的研究主题、热点、常态研究领域和新出现领域,为军队医院今后制定研究方向提供参考。     

The risk of Parkinson’s disease in inflammatory bowel disease: A systematic review and meta-analysis

Background

Several studies have reported an increased prevalence of Parkinson disease (PD) amongst patients with inflammatory bowel disease (IBD) with conflicting results. We aimed to evaluate the risk of PD in the IBD population by conducting a meta-analysis (MA).

Recurrent pain in children, socio-economic factors and accumulation in families

The aim of this study was to estimate the prevalence of parent-reported pain among children in the Nordic countries in 1996, and to describe the association between recurrent pain in children and parental socio-economic factors. We also wanted to estimate the association between parental pain and childhood pain and co-occurrence of different pain patterns in the same child. Data were obtained from a cross-sectional survey on children's health and well-being in the Nordic countries in 1996. About 10, 000 children aged 2–17 years of age were selected from population registries. Mean response rate was 68%. We selected the cases 7 years where the respondent was the child's biological mother or father, yielding a total of 6230 subjects. The adjusted analyses were performed using logistic regression in SPSS. The total prevalence of headache, abdominal pain and back pain among children 7–17 years of age was 14.9, 8.3 and 4.7%, respectively. The most common pain combination was headache and abdominal pain. Pain was most frequent among girls. The prevalence was slightly higher in low educated or low-income families compared to those of high status. Children living in low educated, low-income, worker families had approximately a 1.4-fold odds of having pain. There was a strong association between the different pain conditions, and between pain and other forms of distress in the same child. A site-specific association between parental and child pain was also shown, but we assume that this might have been mediated through subjective (information) bias.     

医疗云相关SCI论文主题词聚类分析

检索与医疗云相关的SCI论文,分析当前该主题相关研究方向。对Web of Science^TM核心合集数据库中该主题SCI论文进行文献计量学分析,统计高频主题词在同一文献中的出现频率并生成共现矩阵,使用SPSS对矩阵各类文献内容进行聚类分析,进而获得该主题的研究方向。     

国际健康素养领域研究现状、热点与前沿的可视化分析

利用文献统计分析、共现分析、同被引分析及可视化手段,探讨国际健康素养领域研究现状、热点与前沿。指出健康素养的内涵与评估、公众健康素养与健康产出的关系、健康教育和健康促进、评估工具的适应性及其改进和应用等是健康素养领域的研究热点。