中医养生方法的归类及其内涵和特色

以中医文献特别是《内经》为基础,从形神兼养、因时因地、因人而养三方面分类概括中医养生诸法,讨论其内涵和特色。认为形神兼养诸法多源于道、儒、释,特别是道家,主要着眼于身心的调整和摄养;因时因地制宜和因人而养较具中医养生特色,特别是后者中医的优势更大。中医养生在养生方法上与道、儒、释养生多兼融交错,它是在总结道、儒、释各家养生文化基础上的发展和集大成。     

对“在卫汗之可也”的再认识

“在卫汗之可也”出自温热大师叶天士《温热论》,是叶氏为卫分证所提出的治疗大法。其中“在卫”表明阶段,可通过阶段分析法、综合分析法、排除分析法、寒温详辨法四种方法判断;“汗之”明确了卫分证的治则,即导邪外出;“可也”暗含禁忌,用药须中病即止。     

内窥镜鼻窦外科手术治疗后组筛窦及眼球后病变38例临床探讨

 目的 探讨内窥镜鼻窦外科手术治疗后组筛窦及眼球后病变的疗效.方法 使用国产内窥镜对38例(42侧)病人施行手术治疗,其中鼻窦炎鼻息肉30例(34侧)、外伤5例(5侧)、肿瘤3例(3侧).肿瘤病人术后结合放疗/化疗.结果 按照海口会议(1997)临床分型分期标准,鼻窦炎鼻息肉治愈率83.33%、好转10.0%、无效6.6%,外伤病人术后眼部症状消失、视力提高4.2～5.0,肿瘤病人术后随访24～48个月无复发.结论 内窥镜鼻窦外科手术是治疗后组筛窦及眼球后病变的理想方法.强调术前CT扫描检查、术中掌握技术操作及术后局部换药处理.     

基于生物多样性保护条件下的旅游资源开发研究--以湖北九宫山自然保护区为例

本文讨论了生物多样性的概念和研究内容,对九宫山自然保护区内的生物多样性观状进行了系统的调查和论述,提出了在生物多样性保护下的自然保护区旅游资源开发战略和功能分区模式。     

Evaluation of drug efficacy of DPP‐4 inhibitors based on theoretical analysis with pharmacokinetics and pharmacodynamics

Dipeptidyl peptidase‐4 (DPP‐4) inhibitors are used clinically as therapeutic agents for the treatment of diabetes. To determine the rate of DPP‐4 inhibition induced by these inhibitors, pharmacokinetic and pharmacodynamic parameters were used to theoretically examine the relationship between the rate of DPP‐4 inhibition and clinical efficacy following the administration of four different DPP‐4 inhibitors (sitagliptin, vildagliptin, alogliptin, linagliptin) by focusing on the increase in the level of glucagon‐like peptide‐1 (GLP‐1) induced by their administration. On the basis of the relationship shown, changes in clinical efficacy in association with dose change were examined in order to discuss clinical dosage from the standpoint of proper usage. The results indicate that a high rate of DPP‐4 inhibition is necessary for the onset of the effect of an administered the DPP‐4 inhibitor and that the average value for the DPP‐4 inhibition rate can be utilized as a common parameter of clinical efficacy. Furthermore, the efficacy profiles of the present DPP‐4 inhibitors could be demonstrated on the basis of an increase in the GLP‐1 level. It is considered that the present findings provide useful information for promoting the proper clinical use of DPP‐4 inhibitors. Copyright © 2016 John Wiley & Sons, Ltd.     

上肢血栓闭塞性脉管炎1例

1病例资料患者,女,55岁,因左前臂紫绀、疼痛2 d于2010年5月21日入院。患者于2天前无明显诱因出现左前臂紫绀、疼痛,左3、4、5指远节发黑。既往有长期吸烟史。查体：生命体征平稳,左前臂紫绀,左3、4、5指远节发黑,左前臂中、远1/3交界以下皮温降低,左3、4、5指远节皮肤干燥,触、痛觉明显减退,左桡     

缝合神经的指固有动脉背支血管链皮瓣修复指远端皮肤缺损

目的 探讨缝合神经的指固有动脉背支血管链皮瓣修复指远端皮肤缺损的疗效.方法 2008年12月至2009年11月,对24例26指指远端皮肤缺损患者,以指固有动脉背侧支形成的血管链为血供,于近节指体侧方设计皮瓣,皮瓣轴线为指体侧方中线,皮瓣蒂宽0.8～1.0cm,皮瓣转折点为中节指体中远端,逆行转移修复指远端皮肤缺损,皮瓣携带指固有神经背侧支或指背神经与创面指神经断端进行缝合修复,重建手指感觉.结果 术后26指皮瓣均存活.随访时间为6～8个月,皮瓣外形理想,质地良好,感觉恢复优良,两点分辨觉为4～8 mm,患指指间关节平均活动度恢复优良.结论 采用缝合神经的指固有动脉背支血管链皮瓣修复指远端皮肤缺损,操作简单,血供可靠,不牺牲指固有动脉、神经,供区损伤小,术后并发症少,并能重建感觉,是一种理想的手术修复方法.     

介入治疗中晚期肝癌中碘油用量的分析

目的 探讨介入治疗中晚期肝癌中碘油的用量.方法 将64例中晚期肝癌患者按随机数字表法分为2组:A组28例和B组36例.A组患者采用肝固有动脉化疗栓塞术治疗:采用局部麻醉,在大C臂机下将5F肝管推送至肝固有动脉.先将注射用盐酸多柔比星40 mg、注射用顺铂50 mg、氟尿嘧啶1 000 mg在透视下经5F肝管缓慢注入;再...     

整复手法治疗腰椎间盘突出症最佳应用时机

分析腰椎间腰盘突出症3个不同时期临床表现,认为在急性期、缓解期的治疗过程中,过早运用整复手法容易激惹刺激神经根,形成新的炎症水肿,出现疼痛,甚至造成神经损伤。恢复期的特点是腰腿痛基本消失,活动欠灵活,筋骨尚未完全恢复正常。恢复期是整复类推拿手法治疗腰椎间盘突出症最佳应用的时机,体现了中医辨证论治的特色。     

Heat shock protein 90 and its cochaperone, p23, are markedly increased in the aged gerbil hippocampus

In the present study, we compared HSP90 and its co-chaperone, p23, immunoreactivity and their protein levels in the hippocampus between adult (postnatal month 6) and aged (postnatal month 24) gerbils using immunohistochemistry and western blot analysis. HSP90 immunoreactivity was markedly increased in pyramidal cells in the hippocampus proper and in polymorphic cells in the dentate gyrus of the aged group compared to the adult group. p23 immunoreactivity was slightly increased in pyramidal cells of the hippocampus proper and in granule cells of the dentate gyrus in the aged group. In addition, HSP90 and p23 protein levels in the aged hippocampus were much higher than the adult hippocampus. These results indicate that HSP90 and p23 immunoreactivity and protein levels in the hippocampus are distinctively increased in the aged gerbils compared to the adult gerbils.