成功抢救头孢唑林钠静注致呼吸、心跳停止1例

头孢唑林为第一代头孢菌素，抗菌谱广。除肠球菌属、耐甲氧西林葡萄球菌属外，本品对其他G^＋球菌具有良好抗菌活性。肺炎球菌和溶血性链球菌对本品高度敏感。适用于治疗敏感菌所致的呼吸道感染、尿路感染、肝胆系统感染、皮肤软组织感染、感染性心内膜炎以及眼、耳、鼻、喉科感染和败血症、骨髓炎等。其毒性低、疗效好，在临床上应用较为广泛，极少发生过敏性休克。我院抢救成功因使用头孢唑林钠致呼吸、心跳停止1例，现报告如下。     

东北八种老鹳草没食子酸含量比较

采用HPLC法比较东北三省8种老鹳草没食子酸的含量,结果:鼠掌老鹳草中没食子酸含量最高达0.301%,建议可作为老鹳草药用来源。     

DETECTION OF HIGH-PATHOGENICITY ISLAND-HARBORING ESCHERICHIA COLI ISOLATED FROM CHILDREN WITH DIARRHEA DISEASE IN CHINA

[Objective] To investigate the etiologicla status of etiologica status of high-pathogenicity island-harboring Escherichia coil(HPIEC) in dianhea disease among children. [Method] Diarrheagenic Esoherichia coli was isolated and identified from the stool specimens of 1032 children with dianhea diseases by culturing, serotyping, Polymerase chain reaction amplification (PCR), the High-pathogenicity island-harboring Esoherichia coli (HPIEC) was identified by PCR and in situ hybridization. [Results] A total of 652 strains of E.coli isolated from 1032 stool specimens and confirmed by serotyping, PCR and colony hybridization out of which 225 were identified as diarrheagenic E.coil,including 20 EPEC,81 ETEC, 47 SLTEC, 74 ESIEC, and 3 EIEC strains. 112(17.2%)irp2 virulent gene positive E.coli (HPIEC) were detected from the 652 strains, out of which 24 were from the 74 ESIEC strains and 17 from the 47 SLTEC strains. The typical clinical symptoms of children with diarrhea disease caused by HPI- harboring E.coli included anorexia(87.5%) ,abdominal pain(58.0%), diarrhea (75.9%,Over six episoders, mostly of mucous stool a day), and fever(50.9%). [Conclusion] High-pathogenicity island-harboring E.coli is one of the important pathogens of diarrhea diseases in children.     

中药治疗斑秃25例

斑秃病中医又称"油风",俗称"鬼剃头"。笔者用中药益气养血法,配合外用药治疗25例,取得满意效果,兹介绍如下。一般资料 25例中男19例,女6例。年龄小于20岁2例,21～30岁8例,31～40岁11例,大于41岁4例,最小者12岁,最大52岁,平均31.6岁。职业:农民7例,工人3例,教师10例,干部3例,其他     

用升麻属植物提取物或活性部位降低细胞中β-淀粉样多肽水平

以己烷提取升麻，得到己烷可溶部位和不溶部位。此不溶部位可降低细胞中β-淀粉样多肽的水平或分泌。     

003鹰爪花属植物化学成分研究进展

本文就鹰爪花属植物的化学成分及相关的药理活性研究进展作一概述。     

柴胡属5种植物RAPD分析与分类鉴定

目的 探讨正晶柴胡与同属近似种包括柴胡Bupleurum chinense、狭叶柴胡B.scozonerifolium、竹叶柴胡B.marginatum、小叶黑柴胡B.smithii var.parvifolium、大叶柴胡B.longiradiatum5种柴胡属植物鉴定的分子证据。方法 CTAB法提取柴胡属原植物总DNA，以随机引物进行非特异扩增。结果 用随机引物OPA－1（5‘－CAGGCCCTTC－3‘），OPD－8（5‘－GTGTGCCCCA－3‘）和OPD－11（5‘－AGCGCCATTG－3‘）能有效地鉴定这5种柴胡属植物。结论 RAPD法可准确鉴定正品柴胡及其近似种。     

肠杆菌科新种细菌的分离鉴定及致病性研究

报告了从辽宁省部分地区腹泻和感染标本中检出的成团肠杆菌、非脱羧勒克氏菌、克吕沃尔氏菌、彭氏变形菌、霍堆氏肠杆菌的分离、鉴定，药敏试验及致病性研究结果．部分菌株可引起动物、生物模型病变，证明有致病力．与人的腹泻和感染有关．致病性研究中，溶血性阳性率最高，依次为乳鼠灌胃，ＨｅＰ—２细胞、Ｖｅｒｏ细胞病变，兔肠袢结扎．豚鼠角膜侵袭试验无阳性．药敏试验证实，５组细菌抗药谱已很广，临床可用的敏感药物不多，一旦发生感染，治疗将十分困难．