首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   443篇
  免费   20篇
  国内免费   1篇
耳鼻咽喉   6篇
儿科学   11篇
妇产科学   18篇
基础医学   21篇
口腔科学   9篇
临床医学   58篇
内科学   70篇
皮肤病学   9篇
神经病学   29篇
特种医学   13篇
外科学   44篇
综合类   41篇
预防医学   80篇
眼科学   4篇
药学   20篇
中国医学   1篇
肿瘤学   30篇
  2023年   10篇
  2022年   14篇
  2021年   22篇
  2020年   36篇
  2019年   28篇
  2018年   16篇
  2017年   15篇
  2016年   25篇
  2015年   26篇
  2014年   40篇
  2013年   35篇
  2012年   19篇
  2011年   36篇
  2010年   23篇
  2009年   19篇
  2008年   28篇
  2007年   23篇
  2006年   9篇
  2005年   8篇
  2004年   4篇
  2003年   5篇
  2002年   3篇
  2001年   3篇
  1999年   2篇
  1998年   3篇
  1997年   1篇
  1996年   1篇
  1995年   1篇
  1994年   1篇
  1992年   2篇
  1991年   1篇
  1990年   1篇
  1989年   2篇
  1981年   1篇
  1976年   1篇
排序方式: 共有464条查询结果,搜索用时 15 毫秒
91.

Background

Surgical resection is an important factor in the curative treatment of gastric cancer. However a variety of aspects of surgical treatment that potentially influence outcome are still not well defined. This study aims to assess the influence of hospital type, referral pattern and proximal or distal location of the tumour on the ultimate survival.

Methods

From January 1994 to January 2007, a total of 5245 patients were diagnosed with gastric adenocarcinoma in the region of the Comprehensive Cancer Centre North-East Netherlands. Hospitals in this region were categorized into three types: teaching university (TU), teaching non-university (TNU), and non-teaching hospitals (NT). The influence of hospital type, referral for surgery and location of the tumour on the relative survival of operated patients was studied.

Results

Of the 5245 patients, 2334 patients underwent surgery. For operated patients, the 5-year relative survival was 42.5% for the TU versus 34.0% and 35.5% for respectively TNU and NT hospitals (p = 0.064), with no difference (p = 0.38) in relative survival (25.6–31.9%) in the proximal tumours. A significant difference was found between the hospitals in the 5-year relative survival in the distal tumours; 59.7% in the TU versus 36.4% in the TNU and 36% in the NT (p = 0.03 univariate), however this was not confirmed in the multivariate analysis (p = 0.184). High referral centres did not perform better as far as survival is concerned than low referral hospitals.In conclusion the hospital type in our region did not significantly influence outcome of surgery for gastric cancer.  相似文献   
92.
目的了解学龄前儿童的视力和屈光发育状况,探讨该年龄段儿童弱视筛查中的视力和屈光度筛选标准。方法横断面调查研究。对海淀区24所幼儿园3~6岁儿童进行视力和屈光度检查。3岁儿童采用图形视力表,4岁以上用标准对数视力表。屈光度检查用SureSight手持式自动验光仪在自然状态下进行。用M(Q1~Q3)描述各年龄组视力和屈光度的分布特征,用秩和检验比较不同年龄组间视力和屈光度分布差异,以百分位数法确定95%参考值范围。结果球镜度M(Q1~Q3):3岁和4岁均为1.25 D(1.00~1.75 D),5岁和6岁均为1.50 D(1.00~1.75 D),3~6岁不同年龄组间球镜度分布差异有统计学意义(χ2=77.60,P<0.01)。柱镜度:各年龄组均为-0.50 D(-0.75~-0.25 D),不同年龄组间柱镜度分布差异有统计学意义(χ2=60.41,P<0.01),两两比较3岁和4岁组之间差异有统计学意义(Z=-4.75,P<0.008),3岁儿童柱镜度较其他组偏小。视力:3岁为0.6(0.6~0.7),4岁为0.8(0.8~1.0),5岁和6岁均为1.0(1.0~1.0),不同年龄组间视力分布差异有统计学意义(χ2=11 323.87,P<0.01),两两比较各年龄组间差异均有统计学意义(P<0.008),随年龄增长视力逐渐提高。视力正常儿童的球镜度P2.5~P97.5:3岁+0.50~+2.75 D,4岁+0.50~+2.50 D,5岁+0.50~+2.75 D,6岁+0.50~+3.00 D,柱镜度P5:3岁-1.50 D,4~6岁-1.25 D;屈光度正常儿童的视力P5分别为3岁和4岁0.6,5岁和6岁0.8。柱镜度数变化对视力的影响较大,球镜度数变化对视力的影响相对较小。结论视力筛选标准:3岁和4岁<0.6,5岁和6岁<0.8;球镜度筛选标准:3~6岁球镜≤+0.25 D和≥+3.00 D;柱镜度筛选标准:3岁≤-1.75 D,4~6岁 ≤-1.50 D。自然状态下屈光筛查球镜度范围可适当放宽,柱镜度范围应相对严格。  相似文献   
93.

Background

Access to specialty care is critical for patients with advanced stage lung cancer. This study assessed access to cancer specialists and cancer treatment in a broad population of patients with advanced stage lung cancer.

Materials and Methods

Two study samples were extracted from 2 claims databases and analyzed independently: patients aged ≥ 18 years with de novo diagnosis of metastatic lung cancer in the MarketScan database between 2008 and 2014 (commercially insured adult patients; n = 22,268); and patients aged ≥ 65 years in the Surveillance, Epidemiology, and End Results–Medicare database with a diagnosis of advanced non–small-cell lung cancer between 2007 and 2011 (Medicare-insured elderly patients; n = 9651). The study period spanned from 6 weeks before the first lung biopsy tied to the initial lung cancer diagnosis until the end of continuous health insurance enrollment, or data availability, or death.

Results

Among the commercially insured adults (MarketScan), most patients were seen by a cancer specialist within a month of first lung biopsy (80%), 12% were never seen by a cancer specialist, and 6% did not receive cancer-directed therapy. Among the Medicare-insured elderly patients (SEER–Medicare), the proportions were 79%, 4%, and 10%, respectively. Patients seen by a cancer specialist were more likely to receive cancer-directed therapy (95% vs. 92%, P < .001 and 92% vs. 38%, P < .001, respectively).

Conclusion

Between 4% and 12% of patients with advanced stage lung cancer do not have appropriate access to cancer specialist, which appears to negatively affect access to optimal and timely treatment.  相似文献   
94.
95.

Objective

to evaluate the effectiveness of continuing training for traditional birth attendants (TBAs) on their reproductive knowledge and performance.

Setting

Mzuzu Central Hospital in the northern region of Malawi.

Participants and analysis

a total of 81 TBAs trained during 2004 and 2006 in Mzuzu, Malawi received continuing training courses. Their reproductive knowledge was assessed by a structured questionnaire during 2004 and 2007. A multivariate generalised estimating equation (GEE) model was constructed to determine the associations between their reproductive knowledge scores and age, years of education, time since the last training course, test frequency and number of babies delivered.

Findings

from July 2004 to June 2007, a total of 1984 pregnant women visited these trained TBAs. A total of 79 (4.0%) mothers were referred to health facilities before the birth due to first-born or difficult pregnancies. No maternal deaths occurred among the remaining mothers. There were 26 deaths among 1905 newborn babies, giving a perinatal mortality rate of 13.6 per 1000 live births. The GEE model demonstrated that knowledge scores of TBAs were significantly higher for TBAs under the age of 45 years, TBAs with more than five years of education, TBAs who had taken a training course within one year, and TBAs with a higher test frequency.

Conclusion and implications for practice

continuing training courses are effective to maintain the reproductive knowledge and performance of trained TBAs. It is recommended that continuing training should be offered regularly, at least annually.  相似文献   
96.
This paper presents the results of a prospective observational cohort study investigating referral practices to six specialized pain centres (SPCs) in 303 patients with headache (HD), low back pain (LBP), and neuropathic pain (NP). The study was divided into three parts. Part 1: The pain health care history (contacts with general practitioners and specialists, further referrals, time spans, therapies) before first contact with the SPC. Part 2: Reality of pain therapy and management in the SPC (patients’ attrition, interdisciplinarity of therapy and novel therapeutic strategies instigated). Part 3: Follow‐up and assessment of pain levels (NRS, SES), disability scores (PDI), QoL scores (SF 12), and anxiety and depression scores (HADS) at 0, 6 and 12 months. Using an ordinal linear regression model, factors predicting a good treatment outcome were identified. On average it took 3 years of pain symptoms before first consultation with GP. The median time period from the first pain sensations until the appointment in the SPC was 12 years. Nearly half of the referrals to specialists or SPCs were initiated by a non‐professional. In the SPC the medication was changed in 71% of cases. Care was interdisciplinary in only 32%. At 6 and 12 months after the first contact with the SPC, only 20% of the patients had improved with respect to levels of pain and psychometric data. A high degree of chronicity, a history of pain‐associated surgeries and low social support were negative predictors for treatment outcome.  相似文献   
97.
目的分析转诊后未到位肺结核可疑者未到位原因,探讨进一步提高转诊到位率的措施。方法采用统一培训调查员,入户填写调查问卷方法对315例转诊后未就诊肺结核可疑症状者进行调查,使用SPSS10.0软件包进行统计分析。结果完成有效调查问卷181份,未就诊者多为低收入(94.1%)、低学历(80.7%)的社会弱势人群,已在其他医院就诊除外肺结核(54.5%)、自觉症状消失/好转(17.4%)、经济困难(6.6%)、行动不便(6.0%)、交通困难(4.8%)、药店自购药(4.2%)等为患者未就诊的主要原因。结论结核病防治专业机构加大工作的积极性和主动性、在全社会强化健康促进工作、特别是强化免费诊治政策的宣传,不断提高与医疗机构的合作程度、提高医务人员传染病报告卡填写质量,加强对抗结核药品的管理力度等措施以提高转诊患者的到位率。  相似文献   
98.
OBJECTIVE: Otitis media management involves both primary and specialist health care. The present study used data on GP referrals to estimate the proportion of children with otitis media referred from primary to specialist care, study variation in referral pattern and factors that influence GP behaviour. METHODS: Data on general practitioners' view on collaborative aspects of specialist health care was collected in a cross-sectional questionnaire survey among all Norwegian GPs in 2004 (N=1633). The outcome of interest was referral routines for otitis media at first visit and at follow-up. RESULTS: Mean referral for otitis media was 22%, most commonly at follow-up visit. Twenty-seven percent of children with otitis media were sent to ENT departments and 73% to practicing otolaryngologists. Variation in referral pattern among GPs was moderate. GPs with specialty in general medicine had 6% fewer referrals. Separate analysis on referral to practicing otolaryngologists showed that GP work load and availability to practicing specialists increased referral, whereas availability to hospital services reduced the probability. CONCLUSION: In Norway, otitis media management mainly takes place in primary care. Completed specialty in general medicine reduces referrals and non-medical factors influence referral behaviour. We suggest that learning groups may contribute to update knowledge in primary care and fewer referrals to specialists.  相似文献   
99.
目的探索在省级结核病专科医院实施结核病人信息登记、转诊及转报制度的可行性和有效性。方法对2003年7月制定结核病人信息登记制度以来登记、转报的结核病人资料及动态变化进行分析。结果通过该制度的实施,加大了查痰力度,涂阳病人的比例由10.1%提高到23.3%,未查痰病人的比例由66.3%下降至16.5%;登记的结核病人全部转报至病人住址所在地的结防机构。结论结核病人信息登记、疫情报告、转诊和转报这一工作制度在省级结核病专科医院的建立和实施,提高了专科医院医务人员的痰检意识,结核病人信息集中管理以及定期向结防机构的转报,有利于防治机构采取措施对病人的进一步跟踪治疗管理。  相似文献   
100.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号