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981.
982.
正常妊娠及合并胎儿窘迫孕妇与新生儿不同分娩方式时血气及酸碱平衡变化 总被引：4，自引：0，他引：4
对４６例正常妊娠妇女（对照组）和４１例合并胎儿窘迫的足月妊娠妇女（窘迫组），于分娩时进行足背动脉和新生儿脐静脉、脐动脉血气分析；并将阴道分娩和剖宫产时酸碱平衡变化作了比较。结果：两组产妇动脉血除剩余碱（ＢＥ）偏低（＜－３ｍｍｏｌ／Ｌ）外，其余各值均在正常范围内，两组间各项指标比较，差异无显著性；两组脐静脉血气各项指标差异也无显著性；与对照组比较，窘迫组脐动脉血ｐＨ值、氧分压（ＰＯ＿２）、血氧饱和度（Ｏ＿２Ｓａｔ）均明显降低，二氧化碳分压（ＰＣＯ＿２）明显升高（Ｐ＜００５）。与剖宫产比较，两组阴道分娩产妇均显示有轻度代谢性酸中毒并轻度低氧血症，窘迫组胎儿酸中毒现象更为明显，新生儿出生时Ａｐｇａｒ评分≤７分的发生率也较高。提示：缩短产程对改善胎儿窘迫有重要意义。 相似文献
983.
984.
尿钙及尿微量白蛋白检测在妊高征早期诊断中的临床意义 总被引：11，自引：0，他引：11
目的 评价尿钙及尿微量白蛋白检测在妊高征早期诊断中的临床意义。方法 收集９８ 例孕２４～３２ 周健康孕妇的２４ 小时尿样,采用自动生化仪测定尿钙排泄量,放射免疫法测定尿微量白蛋白的排泄量,按最终是否发生妊高征分成妊高征组（１４ 例） 和正常妊娠组（８４ 例） 。结果 妊高征组尿钙排泄量为（１－４３±０－３７） ｍｍｏｌ／２４ｈ ,正常妊娠组为（３－２６±０－７５） ｍｍｏｌ／２４ｈ,妊高征组尿钙排泄量显著低于正常妊娠组（ Ｐ＜ ０－００５） 。妊高征组尿微量白蛋白排泄量为（１２－６８ ±６－８１） μｇ／２４ｈ ,正常妊娠组为（６－０８±３－４８） μｇ／２４ｈ,妊高征组尿微量白蛋白排泄量显著高于正常妊娠组（ Ｐ＜ ０－０５）。结论 在妊高征临床症状出现４～８ 周之前,即出现尿钙排泄量减少及尿微量白蛋白排泄量增多。这一特征可作为妊高征早期诊断的指标。 相似文献
985.
986.
目的 探讨孕鼠高血糖对胎鼠胰岛β细胞分泌胰岛素功能的影响。方法 ２８ 只妊娠 Ｓ Ｄ 大鼠随机分成两组,实验组在妊娠晚期持续性静脉输注高渗葡萄糖;对照组同期输注无菌蒸馏水。采用胎鼠胰岛细胞进行胰岛素抽提实验、胰岛素释放试验及灌流试验,研究胎鼠胰岛β细胞功能的变化。结果 实验组胎鼠每个胰腺内胰岛素平均水平为（３ ３２９ ．８１ ±１６３ ．３９）ｎｇ;单位重量胰腺组织胰岛素水平为（１５８ ．５６ ±２３ ．３４）ｎｇ／ｍｇ。对照组胎鼠胰腺内胰岛素平均水平为（２ ３９０ ．０４ ±１５１ ．３９）ｎｇ ;单位重量胰腺组织胰岛素水平为（１２５ ．７９ ±１７ ．９７）ｎｇ／ｍｇ 。两者比较,差异有显著性（ Ｐ＜ ０ ．０５） 。在低糖或高糖 Ｈａｎｋｓ 液中温育胰腺组织２ 小时,实验组胎鼠胰岛素释放量：低糖时为（２４ ．２２ ±４ ．６３）ｎｇ／ｍｇ ;高糖时为（７３ ．７３ ±５ ．９４）ｎｇ／ｍｇ 。对照组胎鼠胰岛素释放量：低糖时为（２０ ．５２ ±２ ．３１）ｎｇ／ｍｇ ;高糖时为（５３ ．３５ ±７ ．５３）ｎｇ／ｍｇ 。两组比较,差异有显著性（ Ｐ＜ ０ ．０５） 。在胰岛素灌流试验中,实验组胎鼠胰岛素分泌时相高峰出现早且峰值高于对照组。结论 相似文献
987.
Anne Elizabeth Chambers Craig Fairbairn Marco Gaudoin Walter Mills Irene Woo Raj Pandian Frank Z. Stanczyk Karine Chung Subhasis Banerjee 《Reproductive biomedicine online》2019,38(2):159-168
Research question
Circulating soluble LH-HCG receptor (sLHCGR) is a first-trimester marker for screening pregnancy pathologies and predicts premature or multiple births before fertility treatment. Oestradiol per oocyte at ovulation induction predicts IVF treatment outcomes. We asked whether sLHCGR levels are stable during fertility treatment and whether, alone or with oestradiol, they could improve prediction of fertility treatment outcomes.Design
Serum sLHCGR, anti-Müllerian hormone [AMH] and oestradiol were measured in patients undergoing IVF. Antral follicle count before ovarian stimulation and oocyte yield were used to establish sLHCGR– oocyte ratio (SOR), sLHCGR– antral follicle ratio (SAR), oestradiol at trigger per oocyte (oestradiol–oocyte ratio [EOR]) and oestradiol at trigger per antral follicle (oestradiol–antral follicle ratio [EAR]).Results
The relatively stable sLHCGR was negatively related to AMH when oocyte yield was high. The sLHCGR levels were proportional (r?=?0.49) to oestradiol at early cycle (day-3). Pregnancy and live birth were highest at low sLHCGR (≤1.0 pmol/ml) and SOR (≤ 0.1 pmol/ml/oocyte). A total of 86–89% of live births in IVF treatment were within the cut-off parameters of SAR and SOR (0.5 pmol/ml) and EAR and EOR (380 pg/ml). For failed pregnancy, age, SOR and EOR together had positive and negative predictive values of 0.841 and 0.703, respectively.Conclusions
sLHCGR levels are negatively related to AMH when oocyte yield is high. High early cycle sLHCGR is associated with elevated day-3 oestradiol. Low sLHCGR and SOR are indicators of increased clinical pregnancy and live birth rates. Patient age and SOR, combined with EOR, might improve prediction of IVF treatment outcomes. 相似文献988.
Kim Paquette Stephanie Markey Stephanie Roberge Mario Girard Emmanuel Bujold Suzanne Demers 《Journal d'obstetrique et gynecologie du Canada》2019,41(1):59-63
Background
Lower uterine segment (LUS) thickness in the third trimester of gestation is associated with the risk of uterine scar defect at delivery. It was suggested that first trimester residual myometrial thickness (RMT) could also predict uterine scar defect at delivery.Objective
This study sought to correlate the RMT measured at the site of uterine scar in the first trimester with the LUS thickness measured in the third trimester.Methods
This was a prospective cohort study of women with a singleton pregnancy and a single prior low-transverse CS. All participants underwent an evaluation of uterine scar by using transvaginal ultrasound at 11 to 13 weeks, including the presence of a scar defect and measurement of RMT; and a second evaluation at 35 to 38 weeks, combining both transvaginal and transabdominal ultrasound, for the measurement of LUS thickness. Spearman's correlation test was used to compare first and third trimester measurements.Results
A total of 166 eligible participants were recruited at mean GA of 12.7?±?0.5 weeks. We observed an absence of correlation between first trimester RMT and third trimester LUS thickness (correlation coefficient 0.10; P?=?0.20). First trimester RMTs below 2.0?mm and below 2.85?mm are poor predictors of third trimester LUS thickness below 2.0?mm (sensitivity, 8% and 23%; specificity, 98% and 87%; positive predictive value, 25% and 14%, respectively).Conclusion
There is a poor correlation between first trimester RMT and third trimester LUS thickness in women with a previous CS. First trimester RMT should not be used to inform women on their risk of uterine rupture or to guide clinical management. 相似文献989.
M. Diéguez Felechosa C. Sánchez Ragnarsson M. Riestra Fernández P. Suárez Gil E. Delgado Alvarez E. Menéndez Torre 《Clínica e investigación en ginecología y obstetricia》2019,46(1):9-14
Objective
To estimate the effectiveness of selective versus universal screening for thyroid dysfunction (TD) during pregnancy.Material and methods
Cross-sectional study applying a selective screening protocol, based on the presence of TD risk factors (RF), in a cohort of pregnant women with a positive universal screening result in the Oviedo Healthcare District. Two hundred and twenty pregnant women with TD were studied between April 2010 and March 2011.Results
Selective screening identified 83.6% of pregnant women with TD. The most prevalent RF were maternal age ≥ 30 years (70.5%), history of miscarriage (21.8%) and family history of thyroid disease (20.9%). Excluding the age factor, only 51.8% of the pregnant women included in the group had risk factors.Conclusions
Selective screening identifies a high proportion of pregnant women with TD but at the expense of screening a large number of women, so it does not appear to be an effective strategy. 相似文献990.
The purpose of this study was to evaluate the usefulness of low-field MRI pelvimetry and to correlate the results with X-ray
pelvimetry. A total of 19 women underwent low-field MRI pelvimetry. Mediosagittal and transverse planes were used to measure
the diameters of the minor pelvic cavity. Correlations between MRI and X-ray pelvimetry were 0.96 for the sagittal inlet,
0.94 for the sagittal outlet, 0.93 for the transverse diameter (diameter transversa, DT) and 0.94 for the bispinous distance
(interspinous distance, IS). The repeatability of the measurements was good. For fetuses with cephalic presentation it was
also possible to determine the biparietal diameter (BPD). Low-field MRI pelvimetry was well accepted by the patients. The
scanning time was less than 6 min, which is comparable with the time of X-ray examination with two planes. Magnetic resonance
imaging provides a reliable method to image pelvic structures and soft tissue without ionizing radiation.
Received 2 October 1995; Revision received 27 December 1995; Accepted 19 June 1996 相似文献