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61.
Chromosomes in 1620 metaphases of ascitic fluid cells in 20 cases of ovariancarcinoma were analyzed.The results showed that there were marked structuralaberrations aside from significant increase in chromosomal numerical aberrations(85.2%).In the ascitic fluid cells from 12 patients,15 types of marker chromosomes were found,among which t(6;14)(q21;q24)and t(2;6)(q35;p12)were more frequently noted witha rate of 7.84% and 7.59% respectively,which was significantly higher than that of othermarker chromosomes(P<0.01).The findings suggested that,besides t(6;14)(q21;q24),t(2;6)(q35;p12)may also be a specific marker chromosome of ovarian carcinoma. 相似文献
62.
63.
Amyloidaceous ulcerated gingival hyperplasia: a newly described entity related to ligneous conjunctivitis 总被引:2,自引:0,他引:2
A. Y. Gokbuget S. Mutlu C. Scully A. Efeoglu S. R. Porter P. Speight G. Erseven M. Karacorlu 《Journal of oral pathology & medicine》1997,26(2):100-104
Gingival hyperplasia may be genetic, may be acquired as a consequence of exposure to drugs and other agents or may appear as part of a more widespread disorder. Five patients who acquired gingival hyperplasia due to amyloidaceous deposits staining only for fibrin are presented. This appears to be a new entity related to ligneous conjunctivitis. 相似文献
64.
The relationship of gingival crevicular fluid short chain carboxylic acid concentration to gingival inflammation 总被引:2,自引:0,他引:2
R. Niederman Y. Buyle-Bodin B.-Y. Lu C. Naleway P. Robinson R. Kent 《Journal of clinical periodontology》1996,23(8):743-749
Abstract Short-chain carboxylic acids (SCCA; C≤5: e.g., lactic acid, propionic acid, butyric acid) are metabolic by-products of bacterial metabolism which accumulate in the gingival crevice, and exhibit significant biological activity, including the ability to alter gene expression. It has been hypothesized that among the activities of SCCAs are their ability to contribute to gingival inflammation. This concept complements the notion that specific periodontal pathogens are the causative agents of gingival inflammation. To begin testing these 2 hypotheses, we examined the relationship between SCCA concentrations, specific putative periodontal pathogens, and gingival inflammation in medically healthy periodontally diseased subjects. We reasoned that if SCCAs and/or specific periodontal pathogens were causative gingival inflammatory agents, gingival inflammation should increase with increasing concentration of the inflammatory mediator. We also recognized that other clinical variables needed to be controlled for, and an objective quantitative assessment of gingival inflammation used. To accomplish these tasks, sites within subjects were stratified by location and pocket depth, and the following quantified: bacteria] presence; SCCA concentration: and gingival inflammation. The results indicated that gingival inflammation directly and significantly correlated with SCCA concentrations in the maxillary and mandibular molars, incisors and canines (all r≥0.47; all p≤ 0.015; too few bicuspids were available for complete analysis). The relationship between gingival inflammation and SCCA concentration was best described by a natural log relationship. Gingival inflammation did not, however, correlate positively with either the total number of specific putative periodontal pathogens, or the sum of subsets of these pathogens (?0.31 ≤r≤ 0.39; 0.08 ≤p 0.75) for any of the locations. Finally, the SCCA concentration did not correlate with the level of individual or groups of pathogens. These data, together with historical work and other preliminary data, support the hypothesis that SCCA, rather than specific putative periodontal pathogens, may be a causative agent in gingival inflammation. This work may, in part, begin to explain the apparent lack of a direct relationship between current gingival inflammation and the prediction of bacterially mediated periodontal attachment loss. 相似文献
65.
66.
耳脑医用粘合剂是α-氰基丙烯酸正辛酯和α-氰基丙烯酸正丁酯及少量添加剂配伍而成的复合性医用粘合剂。应用此粘合剂粘合修补脑脊液漏27例,其中外伤性脑脊液鼻漏5例,经鼻蝶入路垂体瘤切除术脑脊液漏6例,开颅手术后手术切口脑脊液漏11例,脊膜膨出修补术后脑脊液漏5例。成功25例,成功率93%。应用此粘合剂修补脑脊液漏具有简便、迅速、有效的特点。 相似文献
67.
A 73-year-old woman presenting with persistent swelling of the right knee 30 months after total joint arthroplasty was found to have a Candida parapsilosis infection. Treatment with fluconazole resulted in full recovery. 相似文献
68.
目的:检测β—淀粉样蛋白(β—amyloid protein,Aβ)两种主要成分Aβl-40和Aβ1—42在阿尔茨海默病(Alzheier's Disease,AD)脑脊液中的变化,并探讨其对AD的诊断价值。方法:采用敏感的双抗体夹心酶联免疫吸附法(ELISA),检测54例AD患脑脊液中Aβ的浓度,并与30例正常对照(normal controls,NC)脑脊液中的相应成分进行对比。结果:①AD患脑脊液中Aβ1—42浓度低于正常对照组,而Aβl-40/Aβl—42比值高于对照组;②以脑脊液中Aβ比值及Aβl—42浓度检测诊断AD的敏感性分别为54.51%、90.00%,特异性为84.25%、84.38%。结论:临床上同时检测脑脊液中Aβl—42浓度及Aβ比值可作为早期诊断AD的辅助指标,具有一定的临床应用价值。 相似文献
69.
本文报导了用40只白色短毛家兔所做的动物模拟失重实验,得出各脏器微血管通透性的动态反应曲线。并用微循环研究方法,分析了模拟失重时各脏器微血管功能状态与微血管通透性之间的关系;阐述了各脏器微循环功能变化特点;并对变化机理作了初步探讨。 相似文献
70.