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101.
中药饮片小包装与中药调配 总被引:3,自引:0,他引:3
郭丽萍 《河南中医学院学报》2008,23(5)
目的:改进传统中药饮片调配模式,保证中药汤剂的治疗效果.方法:通过实践,比较中药小包装饮片与中药传统包装饮片的优劣.结果:中药小包装饮片具有质量可靠、减少污染和降低损耗的优势.结论:使用中药小包装饮片,可以提高中药饮片质量,有利于中药调配模式的改革. 相似文献
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Hiyoshi K Takano H Inoue K Ichinose T Yanagisawa R Tomura S Cho AK Froines JR Kumagai Y 《Journal of applied toxicology : JAT》2005,25(1):47-51
Although several studies have reported that diesel exhaust particles (DEP) affect cardiorespiratory health in animals and humans, the responsible components in DEP for the effects remain to be defined. Diesel exhaust particles contain quinones that can catalyse the generation of reactive oxygen species, resulting in the induction of oxidative stress. Oxidative stress can correlate with a variety of diseases and health effects. In the present study, we investigated the effects of phenanthraquinone--a relatively abundant quinone in DEP--on lung inflammation and the local expression of cytokine proteins in mice as a measure of oxidative damage. The animals were randomized into two experimental groups that received vehicle or phenanthraquinone by intratracheal instillation. The cellular profiles of bronchoalveolar lavage fluid (BALF) and local expression of cytokines were evaluated 24 and 48 h after the instillation. Phenanthraquinone challenge revealed an increase in the numbers of neutrophils and eosinophils in BALF as compared to vehicle challenge (P < 0.05 at 48 h post-instillation). Phenanthraquinone induced the lung expression of interleukin (IL)-5 and eotaxin 48 h and 24 h after the challenge, respectively. These results indicate that intratracheal exposure to phenanthraquinone induces recruitment of inflammatory cells, at least partly, through the local expression of IL-5 and eotaxin. 相似文献
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淫羊藿药材HPLC指纹图谱的勾兑研究 总被引:2,自引:0,他引:2
目的:在中药HPLC指纹图谱数据的基础上,对不同来源的中药淫羊藿原药材进行了勾兑研究,寻找提高药材指纹图谱相似度,稳定药材质量的新途径.方法:以道地药材为勾兑目标,药材的夹角余弦相似度为评价指标,使用系统优化的勾兑比例投料进行勾兑实验,采集勾兑药材的HPLC指纹图谱.结果:勾兑后,药材与道地药材的相似度评价结果明显提高,与理论计算的结果一致.结论:相似度差异较大的不同批次中药材通过基于中药指纹图谱的勾兑,相似度评价得到提高,为中药原药材的充分利用提供了新的参考方法. 相似文献
106.
目的:改进传统中药饮片调配模式,保证中药汤剂的治疗效果。方法:通过实践,比较中药小包装饮片与中药传统包装饮片的优劣。结果:中药小包装饮片具有质量可靠、减少污染和降低损耗的优势。结论:使用中药小包装饮片,可以提高中药饮片质量,有利于中药调配模式的改革。 相似文献
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Glucocorticoids block the local allergic response in a variety of ways. However, studies have also shown that glucocorticoids increase in vitro IgE synthesis and that treatment with corticosteroids may result in elevated serum IgE concentrations. The ability of topical glucocorticoids to modulate the mucosal IgE response has not been elucidated. We studied the effect of topical steroid (fluticasone propionate) treatment on the local allergic antibody response induced by challenge with either allergen or diesel exhaust particles (DEP). A parallel group study was performed with ragweed-allergic subjects, each subject serving as his/her own control. Nasal provocation challenges were performed on three groups. One group received ragweed allergen, another diesel exhaust particles, and the third saline. The study was repeated following 1 week of treatment with intranasal fluticasone propionate. Each group received the same challenge as before. The concentrations of total immunoglobulins (IgE, IgG, IgA, and IgM), anti-ragweed antibody, IgE- and IgA-secreting cells, epsilon (epsilon) mRNA, and cytokine mRNAs (IL-2, -4, -5, -6, TNF-alpha, INF-gamma) were measured in nasal lavages performed before and at various time points after challenge. Treatment with fluticasone propionate for 7 days caused a decrease in the concentrations of nasal IgE protein, IgE-producing cells, total epsilon mRNA, and all the cytokine mRNAs tested. Furthermore, treatment with fluticasone propionate inhibited the production of allergen-specific IgE and cytokine mRNAs following challenge with ragweed antigen. However, fluticasone treatment did not significantly inhibit the enhancement of mucosal IgE production or cytokine mRNAs observed following nasal challenge with DEP. These results indicate that 1-week treatment with topical fluticasone propionate was effective in blocking local effects of allergen exposure but was unable to inhibit the adjuvant-like effect of DEP. 相似文献
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