全文获取类型
收费全文 | 339273篇 |
免费 | 30039篇 |
国内免费 | 13842篇 |
专业分类
耳鼻咽喉 | 4156篇 |
儿科学 | 7228篇 |
妇产科学 | 3933篇 |
基础医学 | 45300篇 |
口腔科学 | 15756篇 |
临床医学 | 32064篇 |
内科学 | 45300篇 |
皮肤病学 | 6875篇 |
神经病学 | 18251篇 |
特种医学 | 10080篇 |
外国民族医学 | 171篇 |
外科学 | 37330篇 |
综合类 | 51501篇 |
现状与发展 | 71篇 |
一般理论 | 4篇 |
预防医学 | 10837篇 |
眼科学 | 5860篇 |
药学 | 25093篇 |
127篇 | |
中国医学 | 17518篇 |
肿瘤学 | 45699篇 |
出版年
2024年 | 484篇 |
2023年 | 5045篇 |
2022年 | 6907篇 |
2021年 | 13146篇 |
2020年 | 12256篇 |
2019年 | 11416篇 |
2018年 | 11279篇 |
2017年 | 12286篇 |
2016年 | 12906篇 |
2015年 | 13752篇 |
2014年 | 22334篇 |
2013年 | 26552篇 |
2012年 | 19601篇 |
2011年 | 21735篇 |
2010年 | 18250篇 |
2009年 | 17101篇 |
2008年 | 17337篇 |
2007年 | 17872篇 |
2006年 | 16156篇 |
2005年 | 14683篇 |
2004年 | 12615篇 |
2003年 | 11008篇 |
2002年 | 9001篇 |
2001年 | 7813篇 |
2000年 | 6505篇 |
1999年 | 5563篇 |
1998年 | 4997篇 |
1997年 | 4505篇 |
1996年 | 3999篇 |
1995年 | 3422篇 |
1994年 | 3013篇 |
1993年 | 2422篇 |
1992年 | 2083篇 |
1991年 | 1909篇 |
1990年 | 1534篇 |
1989年 | 1405篇 |
1988年 | 1306篇 |
1987年 | 1073篇 |
1986年 | 960篇 |
1985年 | 1231篇 |
1984年 | 1072篇 |
1983年 | 773篇 |
1982年 | 837篇 |
1981年 | 690篇 |
1980年 | 607篇 |
1979年 | 496篇 |
1978年 | 360篇 |
1977年 | 267篇 |
1976年 | 231篇 |
1975年 | 109篇 |
排序方式: 共有10000条查询结果,搜索用时 62 毫秒
11.
12.
13.
14.
15.
16.
17.
《Transfusion and apheresis science》2022,61(1):103368
The endothelium is a single-layered structure that responds to physical and chemical signals with various factors it synthesizes. In the early days of its discovery, as the inner wall of the vessels, the endothelium was thought to be a simple barrier that lays on the surface. Over time it is discovered that endothelium maintains body homeostasis with the molecules it synthesizes, despite its simple single-layer structure. It has been accepted as an important organ that contributes to the maintenance of vascular tone, cell adhesion, inflammation, vascular permeability and coagulation. Any imbalance in these physiological and pathological events causes endothelial dysfunction. This can cause many diseases such as atherosclerosis, hypertension, diabetes, or it can occur because of these. Endothelial related disorders may also complicate hematopoietic stem cell transplantation (HSCT), which is used to treat various hematologic and neoplastic diseases. These life-threatening complications include graft-versus-host disease, hepatic veno-occlussive disease, transplant-associated thrombotic microangiopathy and diffuse alveolar hemorrhage. They share a similar pathophysiology involving endothelial cells with different clinical presentations. Therefore, current researche on the issue is putting the endothelium under the spotlight for novel markers and treatment options that should be used to monitor or treat at least some of these complications following HSCT. 相似文献
18.
《The British journal of oral & maxillofacial surgery》2022,60(7):890-895
Patients undergoing sentinel node biopsy (SLNB) for early oral squamous cell carcinoma (OSCC) who harbour occult metastases (pN+ve) may be at greater risk of mortality due to prolonged overall treatment times than those identified as pN+ve on elective neck dissection (ELND). A retrospective comparative survival analysis was therefore undertaken to test this hypothesis. Patients were identified from the South Glasgow multidisciplinary team (MDT) database. Group 1 comprised 38 patients identified as pN+ve, or who were false negative, on sentinel lymph node biopsy (SLNB). Group 2 comprised 146 patients staged pN+ve on ELND. The groups were compared with the Kaplan Meier method and Cox proportional hazards model. In addition, a matched-pair analysis was performed. A unique and specifically designed algorithm was deployed to optimise the pairings. No difference in disease-specific or overall survival was found between the groups. Patients undergoing SLNB as the initial neck staging modality in early OSCC and are identified as pN+ve do not appear to be at a survival disadvantage compared with those staged with ELND. 相似文献
19.
20.
The adrenal cortex gives rise to a biologically heterogenous group of neoplasms, each with a distinct morphology, antigen expression and molecular profile. Adrenal cortical adenomas have excellent prognosis and are usually cured by surgical resection alone, while adrenal cortical carcinomas are very aggressive tumors with a poor prognosis regardless of therapy. These tumors are rare and often challenging for a pathologist to diagnose, as significant overlap exists between benign and malignant lesions in some cases. In this review, we attempt to summarize most important histologic and clinical features of adrenal cortical adenomas and carcinomas, clarify the use of different grading systems, the use of special stains and the differential diagnosis for practicing pathologists. Most relevant hereditary syndromes associated with adrenal cortical tumors are listed. Updates in molecular alterations in adrenal cortical neoplasms and hyperplastic diseases as well as their clinical significance and potential therapeutic implications are also discussed. 相似文献