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91.
92.
43株奇异变形杆菌检测及其耐药分析 总被引:1,自引:0,他引:1
目的检测从临床标本中分离的43株奇异变形杆菌对16种抗菌药物的体外活性,以及这些杆菌产超广谱β-内酰胺酶、AmpC酶、金属β-内酰胺酶的情况,正确指导临床合理使用抗生素。方法用API-20E对菌株进行鉴定,双纸片协同试验和确证试验筛选超广谱β-内酰胺酶,纸片扩散法检测AmpC酶,改良Hodge试验检测金属β-内酰胺酶,药敏试验采用标准的纸片扩散法。结果奇异变形杆菌的产酶率为20.9%(9/43)。其中,超广谱β-内酰胺酶为18.6%(8/43),AmpC酶为2.3%(1/43),金属β-内酰胺酶为0。三代头孢菌素、四代头孢菌素、氨曲南、头孢西啶、亚胺培南、阿米卡星和左氧氟沙星的敏感率均大于80%。结论实验室有必要加强对产β-内酰胺酶奇异变形杆菌的检测。三代头孢菌素、四代头孢菌素、氨曲南、头孢西啶、亚胺培南、阿米卡星和左氧氟沙星是治疗奇异变形杆菌感染的首选药物。 相似文献
93.
94.
目的研究奇异变形杆菌(Proteus mirabilis,PM)波动生长过程中生物波调控因子(biological wave regulating factor,BRF)的节律性释放及作用。方法应用MTT实验和激光共聚焦显微镜观察BRF对细菌代谢的影响;采用凝集抑制实验检测PM周期性释放BRF;原子力显微镜观察PM在潜-生序变化中BRF生成情况。结果PM在波动生长过程中周期性释放BRF,潜生体可合成大量的BRF。BRF能提高细菌的代谢水平,促进细胞内pH值的变化。结论PM的波动生长过程是细菌生长代谢的消长与环境平衡-远离平衡变化之间互为因果的动态过程,是与细菌自身调控物质BRF协同作用的结果。 相似文献
95.
Gilles Dautel MD Joel Vialaneix MD Stephane Faivre MD 《The Journal of foot and ankle surgery》2004,43(2):113-118
Macrodactyly involving the great toe is difficult to treat when both the functional and cosmetic problems are addressed simultaneously. Partial resection of the distal phalanx is an easy way to reduce the length of the involved toe. However, there are cosmetic concerns with loss of the toenail. The authors report on a clinical case in which shortening and debulking of the toe was performed while preserving the hallux nail. The nail complex was transferred as an island flap to the dorsal aspect of the proximal phalanx. At the 1-year follow-up, the length of the reconstructed toe was significantly decreased, with a normal-looking nail. 相似文献
96.
Osteomyelitis due to Proteus mirabilis is rare. Spinal osteomyelitis caused by this organism has only been described in adults. This is the first paediatric case
of P. mirabilis vertebral osteomyelitis.
Received: 4 June 1996 / Accepted: 1 July 1996 相似文献
97.
The relationship between growth condition and production of cell-bound hemolysin by Proteus mirabilis 51959 strain was investigated. Hemolytic activity was not dependent on type of medium, oxygen accessibility and was inhibited in presence of N-ethylmaleimide, different sera or trypsine. Cell-free hemolysin was released to the medium during stationary-death phases of growth of fluid Proteus mirabilis and vulgaris cultures.Corresponding author. 相似文献
98.
99.
Frederick A. Jakobiec Roberto Pineda Roxana Rivera Charlene Hsu-Winges David Cherwek 《Survey of ophthalmology》2010,55(1):78
It is remarkable to uncover a new aspect of congenital epibulbar solid dermoids and lipodermoids. We describe a dramatic central epicorneal polypoidal lipodermoid coloboma accompanied by an upper eyelid coloboma that was not associated with Goldenhar syndrome. Histopathologically the excised lesion displayed superficial layers of epidermis and a thin dermis with eccrine glands, vestigial hair structures, and bundles of arrector pili smooth muscle that extended from the undersurface of the epidermis to the bulge area of the primitive hairs. This last feature is not present in normal eyelid skin nor in the conjunctiva, and has not been previously documented to occur in epibulbar dermoids and lipodermoids. S-100-positive dendritic melanocytes and CD1a-positive Langerhans cells were both observed intraepidermally, indicating a complete complement of normal cells in this layer. Beneath the dermis was a massive collection of lobules of mature adipose tissue that fused with the corneal stroma. A virtually identical pedunculated limbal tumor has been previously reported that was associated with Goldenhar syndrome. Review of earlier published cases of epibulbar dermoids and lipodermoids establishes that central corneal lesions are not a stigma of Goldenhar syndrome, in contrast to limbal masses. Other epibulbar choristomas that can be confused with lipodermoids are described. 相似文献
100.
Jinbo Chen Liuqing Chen Yiqun Duan Dongsheng Li Bilin Dong 《The Journal of dermatology》2015,42(2):219-220
Connective tissue nevi represents a kind of hamartoma, and coalescence of the lesions in a cerebriform mode in the lumbar region without Proteus syndrome is rarely seen. Here, we report a 26‐year‐old woman presenting with nodules and plaques in her left lumbar region of 26 years in duration. Histopathological examination and Masson‐trichrome stain showed increased dermal collagen bundles in a haphazard array. The diagnosis of connective tissue nevi was made. This is the first case report on cerebriform connective tissue nevi without Proteus syndrome in the lumbar region. 相似文献