全文获取类型
| 收费全文 | 447篇 |
| 免费 | 24篇 |
| 国内免费 | 21篇 |
专业分类
| 耳鼻咽喉 | 1篇 |
| 妇产科学 | 4篇 |
| 基础医学 | 14篇 |
| 口腔科学 | 16篇 |
| 临床医学 | 10篇 |
| 内科学 | 33篇 |
| 皮肤病学 | 4篇 |
| 神经病学 | 4篇 |
| 特种医学 | 14篇 |
| 外国民族医学 | 1篇 |
| 外科学 | 24篇 |
| 综合类 | 117篇 |
| 预防医学 | 13篇 |
| 眼科学 | 5篇 |
| 药学 | 39篇 |
| 中国医学 | 187篇 |
| 肿瘤学 | 6篇 |
出版年
| 2024年 | 1篇 |
| 2023年 | 5篇 |
| 2022年 | 15篇 |
| 2021年 | 19篇 |
| 2020年 | 16篇 |
| 2019年 | 45篇 |
| 2018年 | 51篇 |
| 2017年 | 26篇 |
| 2016年 | 11篇 |
| 2015年 | 11篇 |
| 2014年 | 35篇 |
| 2013年 | 21篇 |
| 2012年 | 20篇 |
| 2011年 | 27篇 |
| 2010年 | 31篇 |
| 2009年 | 20篇 |
| 2008年 | 5篇 |
| 2007年 | 13篇 |
| 2006年 | 12篇 |
| 2005年 | 7篇 |
| 2004年 | 14篇 |
| 2003年 | 11篇 |
| 2002年 | 8篇 |
| 2001年 | 5篇 |
| 2000年 | 10篇 |
| 1999年 | 4篇 |
| 1998年 | 3篇 |
| 1997年 | 4篇 |
| 1995年 | 14篇 |
| 1994年 | 2篇 |
| 1993年 | 2篇 |
| 1992年 | 3篇 |
| 1991年 | 6篇 |
| 1990年 | 1篇 |
| 1989年 | 2篇 |
| 1987年 | 1篇 |
| 1983年 | 3篇 |
| 1982年 | 1篇 |
| 1981年 | 3篇 |
| 1980年 | 2篇 |
| 1976年 | 1篇 |
| 1973年 | 1篇 |
排序方式： 共有492条查询结果，搜索用时 31 毫秒
41.
42.
基于药物代谢组学的中药及方剂中组分间协同增效作用 总被引：1，自引：0，他引：1
针对中药及方剂中多组分间配伍协同作用的特点，提出了利用药物代谢组学解析多组分间协同增效作用的机制的假说，并介绍了作者近期利用药物代谢组学研究方剂及组成药物相互关系的成果。 相似文献
43.
刘完素的《三消论》是现存最早的消渴专书,另一本署名完素的著作《素问病机气宜保命集》中也有描写消渴诊治的专论,但比较此二论著的内容后,发觉其论述的角度迥异,不似由同一人所写,且目录学考证的结果或薄弱或分歧,无法辨别真伪。再借助于完素的《黄帝素问宣明论方》里消渴资料的分类比对,发现《三消论》和《宣明论方》的描述相当一致,此二书应当是出自刘完素之手。相对而言,《素问病机气宜保命集》的写作方式则明显不同于前二者,不大可能是刘完素的作品。 相似文献
44.
45.
46.
Background
A longer time in consultation with doctors in ambulatory care has been associated with better quality of care. Patient experience is of great concern to policy makers and is linked with health-care quality. However, the relationship between consultation length and patient experience remains unclear. We aimed to investigate the effect of consultation length on patient experience, based on analysis of a cross-sectional nationwide patient survey data in China.Methods
We obtained patient survey data from a strati?ed nationwide survey sample that covered 136 tertiary hospitals in China. Patient-estimated consultation length and associated patient experience data were collected by questionnaire after each patient attended a face-to-face consultation with a doctor. The consultation experience was rated on a 5-point scale. We applied a two-piecewise linear regression model to examine the saturation effect of the consultation length on patient experience (consultation score), using a smoothing function, while age, sex, education, and profession were adjusted in the model, then estimated the turning point that gave the maximum model likelihood by using trial and error.Findings
Between Dec 18, 2017, and Dec 30, 2017, 27?721 patients, aged 15–85 years, were eligible and selected for inclusion. The median patient-reported duration of face-to-face ambulatory care consultation was 10 min (IQR 5–12), and the mean score of the consultation experience rated by the patient was 4·25 (SD 0·83; 95% CI 4·24–4·26) on the 5-point scale. After adjusting for potential confounders including age, sex, education, and profession, there was a non-linear relationship between consultation length and measure of patient experience after smooth curve fitting. A turning point at 8 min was identified in the modelling process. Below this point, there was a higher probability of rating a consultation score above average with longer consultation length (odds ratio [OR] 1·28, 95% CI 1·26–1·30, p<0·001). After this point, the OR changed to 1·03 (95% CI 1·02–1·04, p<0·001). There was a significant difference in patient experience measure before and after this consultation length turning point (p<0·001).Interpretation
Consultation length was associated with a measure of patient experience in a non-linear pattern. Longer consultations might not be required to achieve better patient experience, but an adequate consultation should not be shorter than 8 min. Future research about the appropriateness of consultation length for varies ambulatory care institutions would be of benefit.Funding
National Natural Science Foundation of China (71532014), National Health Commission of China 相似文献47.
目的 观察柴芍六君汤、拉米夫定联合治疗慢性乙型肝炎患者YMDD变异的情况.方法 采用非随机同期对照试验,将405例慢性乙型肝炎患者分为治疗组和对照组,治疗组220例,对照组185例,对照组给予拉米夫定100 mg,每天1次,口服,治疗18个月.治疗组给予柴胡六君汤每日1剂,同时口服拉米夫定100 mg,每天1次,治疗18个月.观察患者临床症状、ALT复常率、HBeAg阴转率,HBeAg血清转换率,HBV DNA阴转率、治疗12个月及18个月的YMDD变异率.率的比较采用χ2检验,均数比较采用t检验或U检验,方差不齐者用秩和检验. 结果治疗3.6、12.18个月时,ALT复常率治疗组分别为69.5%、85.9%、90.5%,82.7%,对照组分别为50.3%、65.4%、78.4%,69.7%,两组比较,χ2值分别为15.70、23.50、11.50.9.50.JD值均<0.01,差异均有统计学意义.治疗组12、18个月HBV DNA阴转率、HBeAg阴转率、HBeAg血清转换率、YMDD变异率分别为77.7%、57.7%、25.5%、6.8%和86.8%、74.1%、33.2%、8.6%,对照组分别为54.6%、36.8%,13.O%,14.6%和69.2%、37.3%、19.5%、20.5%,两组比较,χ2值分别为24.38、17.70、9.88、6.54和18.67、55.60、9.62,11.78,P<0.01或P<0.05,差异有统计学意义. 结论柴芍六君汤联合拉米夫定治疗慢性乙型肝炎,能有效地改善肝功能,提高拉米夫定抑制HBV复制的作用,减少YMDD变异的发生. 相似文献
48.
目的：观察子午流注择时温和灸联合中药敷脐防治胃肠道恶性肿瘤化疗所致胃部不良反应的临床疗效。 方法：将120例胃肠道恶性肿瘤化疗患者随机分为对照组和观察组,每组60例。对照组患者在化疗期间常规给予制酸剂和止吐药物,观察组在对照组干预措施基础上,根据子午流注择时给予温和灸法和中药敷脐;观察两组患者胃部不良反应情况。 结果：化疗期间,观察组、对照组恶心、呕吐及食欲减退等胃部不良反应发生率分别为51.7%和80.0%,观察组胃部不良反应发生率及胃部症状分级均低于对照组(P<0.05)。 结论：子午流注择时温和灸联合中药敷脐能有效防治胃肠道肿瘤化疗所致的恶心、呕吐及食欲不振等胃部反应。 相似文献
49.
Background
In China, patients increasingly choose to access severely overcrowded higher level hospitals, whereas the lower level facilities often have low frequencies of use. This situation undermines effectiveness and efficiency of the health system. Moreover, the situation tends to worsen despite policy measures aimed at improvement. We therefore aimed to systematically review the factors affecting patient choice of health system access in China to synthesise scientific understanding.Methods
We did a systematic review of peer-reviewed literature that investigated Chinese patients' choice of health-care facilities at different levels. We searched Embase, MEDLINE, Web of Science, and PubMed for English language articles, and three large Chinese databases (CNKI, VIP, and Wanfang) for articles in Chinese between April 1, 2009, and Jan 28, 2016, using search terms related to patients' choice of health-care facility access level, and how these factors affect the choice of level, such as health care access, decision making in health care, and health seeking behaviour. The primary outcome was to identify the factors that influenced patient choices of health system access level in China. Two structured forms were used to extract data from eligible studies, regarding the study characteristics, methodology, and factors. We appraised the methodological quality of the studies using Method Appraisal Tool (MMAT).Findings
We identified and included 45 studies into our analysis. We identified four types of factors related to patient, provider, context, and composite factors from multiple types. Patient factors are mentioned in 31 (69%) of 45 studies, but the evidence on patient factors is mostly inconclusive. Context factors were the least frequently mentioned, and were reported in four (9%) studies. Evidence suggests that the provider factors, such as drug variety and equipment, and composite factor, such as perceived quality, push patients from lower levels towards higher levels. The MMAT quality score was 100% for 13 studies, 75% for 25 studies, 50% for six studies, and 25% for one study.Interpretation
This systematic review provides an evidence base for measures to redirect patient flow from high level health-care facilities to lower level facilities, thus improving effectiveness and efficiency of the Chinese health system. The underuse of primary care facilities in the Chinese health system compromises the effectiveness and efficiency, and are likely to be amplified by current demographic trends. Evidence suggests that improving the drug availability, equipment, and perceived quality of primary care services can improve the situation. Our evidence suggests that further experimental research is needed, which also considers interactions between factors.Funding
This study was partly funded by the China Scholarship Council (grant number 201507720036). 相似文献50.
Feng Jiang Huixuan Zhou Linlin Hu Tingfang Liu Shichao Wu Pengyu Zhao Guangyu Hu Huanzhong Liu Yilang Tang Yuanli Liu 《Lancet》2018