生精片治疗少弱精子症疗效观察45例

目的探讨生精片治疗少弱精子症的疗效与安全性。方法 90例少弱精子症患者随机分为两组,治疗组45例,口服生精片;对照组45例,口服维生素C与维生素E。各组均在治疗3个月后评定疗效。结果临床疗效总有效率治疗组为91.8%,对照组为15.3%,两组比较,差异有显著性意义(P<0.01)。治疗组精子密度及前向运动率明显增高。结论口服生精片治疗少弱精子症疗效显著,无不良反应。     

生脉注射液辅助治疗支气管哮喘急性发作47例疗效观察

目的探讨生脉注射液辅助治疗支气管哮喘急性发作的临床效果。方法选择2008年1月至2009年12月92例支气管哮喘急性发作患者,随机将上述患者分为两组,观察组和对照组。对照组患者给予支气管哮喘急性发作常规治疗：解痉、平喘、糖皮质激素、控制感染等;观察组在对照组治疗的基础上给予生脉注射液60ml加入250ml生理盐水中静脉滴注,每天1次。两组患者共治疗14天。在治疗期间观察患者临床症状改善情况,并定期测定患者肺功能。结果两组患者总有效率比较,差异有统计学意义,P〈0.05。结论生脉注射液辅助可以显著改善支气管哮喘急性发作期患者临床症状,提高肺功能,临床治疗效果显著,值得借鉴。     

芪莲舒痞颗粒对食管黏膜异型上皮样变的逆转作用研究

目的探讨芪莲舒痞颗粒对食管黏膜异型上皮样变的逆转作用研究。方法选择山东省消化病防治中心和河南科技大学第三附属医院诊断的食管黏膜异型上皮样变者100例,随机分成两组,一组（治疗组）口服芪莲舒痞颗粒,每次2袋,日3次冲服。对照组口服胃复春片,每次4片,日3次。疗程均为3个月。所有患者在治疗前及疗程结束后2周内作胃镜及病理检查。常规病理对胃黏膜萎缩、肠化、异型增生,按轻、中、重分别记分为1、2、3分,各部位组织得分之和为各项目之总积分。结果比较两组病人治疗前后的胃镜下组织黏膜图像变化,结果发现,芪莲舒痞颗粒与对照组均能明显改善胃镜下组织黏膜的图像,差异均有显著性（P〈0.05）;比较两组治疗后的胃镜下组织黏膜图像的变化,结果发现,治疗组疗效明显优于对照组（P〈0.05）。结论芪莲舒痞颗粒对食管黏膜异型上皮样变有明显的逆转作用,优于既往的常规中药治疗。     

自拟回乳贴中西医结合回乳临床观察

[目的]探讨回乳的有效方法。[方法]应用维生素B6口服结合自制中药回乳贴外敷乳房局部治疗120例需要回乳的患者。[结果]120例患者经治疗5天后效果明显。[结论]维生素B6口服结合自制中药回乳贴外敷乳房效果显著。     

Preliminary Comparative Study on the Effect of Different Chinese Drugs for Strengthening Pi(脾)in Antagonizing Diet Induced Obesity

<正>Objective:To observe the difference in fatty degree,glucose-lipid disorder and adipose-hormones between diet induced obesity(DIO) rats and diet induced obesity resistance(DIO-R) rats,and to explore the effect and acting mechanism of Chinese drugs for strengthening Pi(脾,CD-SP) and those for both strengthening Pi and dissolving phlegm(CD-SPDP) in inhibiting obesity.Methods:Excepting eight rats allocated in the blank control group,the other 54 rats were fed with high-lipid forage for 12 weeks to establish models of obesity. Finally,30 DIO rats and 8 DIO-R rats(shown by their body weight) were obtained.The DIO rats were divided into three groups,which were given gastric perfusion,respectively,with normal saline(Group A),CD-SP(Group B),and CD-SPDP(Group C).Fourteen weeks later,the animals' body weight(BW),length(BL),blood levels of fasting insulin(Fln),fasting glucose(FBG),triglyceride(TG),cholesterol(TC),leptin(LP),neuropeptide Y(NPY), C-reactive protein(CRP),tumor necrosis factor-α(TNF-α),adiponectin(AN),and resistin(RS) were measured; insulin resistance index(IRI) was calculated,and the degree of obesity and lipid content in abdominal cavity of rats were estimated.Moreover,the levels of LP,CRP,TNF-α,AN and RS in homogenate of rats' adipose tissues(ATH) were determined.Results:After 12 weeks of high-lipid diet,the BW of DIO rats was higher than that of normal or DIO-R rats.After a 14-week continuous high-lipid diet feeding,in DIO rats,BW,lipid coefficient (LC),and IRI were significantly increased(P0.01);serum levels of TNF-α,LP and AN were lower,NPY was higher,while the ATH levels of LP and AN were lower and TNF-αwas higher in DIO rats than in DIO-R rats (P0.05 or P0.01);blood levels of FBG and lipids in DIO rats showed an increasing trend but was statistically insignificant(P0.05);no significant difference was found in serum levels of CRP and RS due to the overly high data dispersion.Comparisons of the 3 DIO groups showed that BW,body weight index(BWI),LC and IRI were significantly lowered after treatment(P0.01) in Group C,while these indexes were not significantly different between Group A and B;the serum levels of TNF-α,LP,and AN increased,NPY decreased in Group B and C, ATH levels of LP and AN increased,and TNF-αdecreased in the two groups;but NPY,LP,and AN in blood and ATH were higher in Group C than those in Group B(P0.05 or P0.01).Conclusion:CD-SPDP could inhibit DIO and IR,showing that the effect is better than that of CD-SP,and its mechanism is related to promotion of LP and AN secretion and elevation of serum NPY.     

外伤性鼓膜穿孔实施贴敷法治疗的临床观察

目的探讨采用鸡蛋内膜贴敷法治疗外伤性鼓膜穿孔的疗效。方法165例（168耳）外伤性鼓膜穿孔患者随机分成治疗组（鸡蛋内膜贴敷法）82耳和对照组（传统干燥疗法）86耳。对照组予口服抗生素预防感染;治疗组在此基础上,用备好的鸡蛋内膜片贴敷于鼓膜穿孔周围的鼓膜面上,使其完全敷盖穿孔,根据穿孔大小择期取下贴敷材料或重新贴敷来观察鼓膜愈合情况。结果治疗组治愈率95％,对照组治愈率78％,两组比较差异有统计学意义（P〈0．05）。治疗组平均愈合时间（36±23）d,对照组平均愈合时问（52±26）d,治疗组穿孔愈合时间明显短于对照组（P〈0．05）。结论采用鸡蛋内膜贴敷法治疗外伤性鼓膜穿孔,不仅可缩短鼓膜穿孔愈合时间,且能明显提高治愈率。     

中医“象”的特点

"象"指事物在自然本体状态下的呈现,对"象"规律的揭示和研究,可称之为象科学。"象"具有动态性、自然性、物我合一性和整体性四个特点。"象"是中医观察和研究的主要对象。中医"象"的思维方式注重体验、直觉和悟性,这种思维方式是立体的、混沌的、意象的和体验的。其特色主要体现在生命的精神层面、功能层面、整体层面和动态层面。     

复方南星止痛膏治疗寒湿痹阻型膝关节骨关节炎临床观察

目的观察复方南星止痛膏治疗寒湿痹阻型膝关节骨关节炎的临床疗效。方法将150例患者随机分为三组,分别采用局部外敷复方南星止痛膏治疗、局部外敷骨痛贴膏治疗、患处局部热敷。结果三组治疗后VAS评分均有明显下降,与自身治疗前比较,差异有统计学意义(P<0.05)。结论复方南星止痛膏对寒湿痹阻型膝关节骨关节炎患者疼痛的治疗效果确切,副作用小。     

三伏贴治疗咳喘病的临床研究

[目的]评价穴位贴敷治疗咳喘病的临床疗效。[方法]测定144例病人治疗后的中医症状评分和肺功能（FEV1、PEF、FEV1%）,比较治疗前后评价指标的差异,及其与年龄、性别及中医证型的关系。[结果]治疗后患者的症状评分肺功能均有明显地改善。[结论]三伏贴治疗前后患者的临床症状明显改善,并且肺功能指标同样得到改善。     

我院生脉注射液不良反应分析

目的：分析生脉注射液引起的不良反应（ADRs）,为临床合理用药提供参考。方法：收集本院2005～2008年以来,内科、外科、骨伤科、妇产科和门诊应用生脉注射液,按卫生部ADR判定标准筛选的ADR病例56例,并进行分类整理。结果：生脉注射液的ADRs主要有过敏性皮疹、腹胀、腰背剧痛、心动过速和低血压等。结论：生脉注射液引起ADRs的原因较多,但相关报道较少,临床应用时应加以重视,加强监测,减少ADRs的发生。