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991.
M Wall 《Pediatric pulmonology》1989,6(2):71-73
The question of whether functional residual capacity (FRC) falls in infants during active sleep has been clouded by studies using different subject groups and techniques for measurements of lung volume and determination of sleep state. Twenty healthy full-term infants within the first week of life participated in the present study. Neurophysiological and behavioral criteria were used to define sleep state, and measurements of FRC were made using a specially constructed closed-circuit helium dilution system. Regularity of respiration was recorded using magnetometers on the chest and a modified respirator monitor. Results showed that no significant changes in FRC occurred, related either to sleep state or to regularity of respiration. In addition, we failed to detect any differences in FRC between the sexes. Pediatr Pilmonol. 1989; 7:71–77 . 相似文献
992.
J C Henry T van Amelsvoort R G Morris M J Owen D G M Murphy K C Murphy 《Neuropsychologia》2002,40(5):471-478
Velo-cardio-facial syndrome (VCFS) is associated with deletions on the long arm of chromosome 22, mild intellectual disability, poor social interaction and a high prevalence of psychosis. However, to date there have been no studies investigating the neuropsychological functioning of adults with VCFS. We compared 19 adults with VCFS with 19 age, gender and IQ matched controls using a comprehensive neuropsychological battery. Compared to controls, adults with VCFS had significant impairments in visuoperceptual ability (Visual Object and Space Perception Battery), problem solving and planning (Tower of London) and abstract and social thinking (Comprehension WAIS-R). It is likely that haploinsufficiency (reduced gene dosage) of a neurodevelopmental gene or genes mapping to chromosome 22q11 underlies the cognitive deficits observed in individuals with VCFS. 相似文献
993.
目的 采用改进的Mitchell术式矫正拇外翻畸形。方法 对Mitchell术式进行改进 ,术中缩短第 1跖骨 ,内侧舌状骨瓣旋后外翻嵌入截骨近端髓腔 ,拇收肌联合腱移位于第 1跖骨头外侧 ,并松解第 1跖趾外侧关节囊等综合整形。结果 共 63例 (1 0 1足 )应用Mitchell术式并得到 2年以上的随访 ,总优良率达 91 % ,疗效满意。结论 本术式针对拇外翻畸形的病理解剖及其症状多方面矫正 ,使术后的外形和功能得到全面改善 ,可同时适用中老年患者 相似文献
994.
股骨近端带锁髓内钉在粗隆间骨折的应用 总被引:25,自引:3,他引:22
目的评价股骨近端带锁髓内钉(ProximalFemoralNail,PFN)治疗股骨粗隆周围骨折的临床疗效。方法对72例股骨粗隆周围骨折的治疗作回顾性总结分析。其中男29例,女性43例。年龄64~96岁,平均78岁。在本组粗隆周围骨折的分型中,EvenⅠ型16例、Ⅱ型31例、ⅢA型14例、ⅢB型6例、Ⅳ型3例。其余2例为粗隆下骨折。结果随访自出院以后超过6个月的患者65例,除一例患者因患有严重的骨质疏松而出现拉力螺钉脱出并髋内翻外,其余患者拍片显示骨折已愈合,生活能够自理,临床疗效满意,骨折平均愈合时间为8周。结论PFN是治疗股骨粗隆周围骨折的一种较好的内固定方法,为股骨粗隆部位的骨折创造了理想的愈合条件,由于其并发症低,手术操作简便,符合微创技术的治疗要求,值得临床推广应用。 相似文献
995.
David Mischoulon Darin D. Dougherty Kathryn A. Bottonari Robert L. Gresham Shamsah B. Sonawalla Alan J. Fischman Maurizio Fava 《Psychiatry Research: Neuroimaging》2002,116(3):151-161
Nefazodone has been widely used as an antidepressant, but it has not been tested for depression with anger attacks. In an open study, we administered nefazodone (maximum 600 mg/day) for 12 weeks to 16 outpatients who had major depression with anger attacks. Assessment instruments comprised the Structured Clinical Interview for DSM-IV (SCID), Anger Attacks Questionnaire (AAQ), 17-item Hamilton Rating Scale for Depression (HAM-D-17), Clinician Global Impression Scale (CGI), Symptom Questionnaire (SQ), Modified Overt Aggression Scale (MOAS), and MOAS-Self-Rated. Three subjects underwent positron emission tomography (PET) with [18F]-setoperone for 5-HT2 binding potential (BP) and [11C]-SCH-23,390 for D1 BP, both at baseline and after 6 weeks of treatment. Eight subjects underwent PET with [18F]-setoperone and with [11C]-SCH-23,390 at baseline only. In an examination of whether D1 and 5HT2 (data available in six subjects) receptor BP predicted treatment response, we found significant decreases in the HAM-D-17, CGI-S, weighted MOAS, MOAS verbal scale, OAS Self-Rated verbal, SQ Depression and Anger/Hostility scales after nefazodone; 50% responded to nefazodone (defined as ≥50% decrease in HAM-D-17 score), and 44% reported disappearance of anger attacks. A statistically significant percentage decrease in 5HT2 BP was observed for the right mesial frontal and left parietal regions after 6 weeks of treatment. No significant change was observed in D1 BP in any region. Although CGI-I scores correlated significantly with D1 BP in the left thalamic region, the correlation was not significant after Bonferroni correction. The effectiveness of nefazodone for depression with anger attacks may be related to widespread changes in 5HT2 receptor BP. 相似文献
996.
目的 探讨羧乙基锗倍半氧化物(Ge-132)在乙醇致体内脂质过氧化过程的抑制作用及机理。方法 用10mg/kg体重的乙醇给大鼠灌胃,同时自由饮用100mg/L的锗-132,饲养3个月。结果 乙醇+Ge-132组大鼠组织和血清与单给乙醇组比较DMA含量显著降低(P<0.05),SOD、CAT活力均升高(P<0.05),但与对照组比较均无显著性差异(P>0.05)。结论 Ge-132通过清除OH^.和O2^.-自由基,抑制SOD、CAT活力降低,从而抑制过量乙醇对机体的损伤。 相似文献
997.
998.
本文主要研究了无机玻璃纤维增强聚甲基丙烯酸甲酯(PMMA)/羟基磷灰石(HA)复合材料的制备及相关的性能测试,证明此复合材料性能稳定、物理机械强度高以及工艺简单,有良好的应用前景。 相似文献
999.
1000.
Intracranial trajectories of sympathetic nerve fibers originating in the superior cervical ganglion (SCG) in the rat were investigated by means of anterograde labeling following the injection of wheat germ agglutinin-horseradish peroxidase conjugate (WGA-HRP) into the unilateral SCG. The trajectory of the sympathetic fiber innervating the pineal gland and its continuing structures was found advancing along the abducent nerve, through the cavernous plexus, then along the trochlear nerve. Labeled sympathetic fibers showed two patterns of distribution in the blood vessels on the basal surface of the brain. The sympathetic fibers originating in the unilateral SCG were intermingled with those fibers from the contralateral SCG in the pineal gland, its continuing structures and the choroid plexus of the third ventricle as well as in the cerebral blood vessels. 相似文献