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61.
David H. Miller M.D. Theodore T. Miller M.D. Elizabeth Schultz M.D. Baruch Toledano M.D. 《Emergency radiology》1997,4(3):172-176
We report a case of dislocation of the second through fifth carpometacarpal joints and review the mechanism of injury and radiographic findings in such injuries. 相似文献
62.
Oguzkan Sürücü Ulrich Sure Sabine Gaetzner Sonja Stahl Ludwig Benes Helmut Bertalanffy Ute Felbor 《Child's nervous system》2006,22(11):1461-1464
Introduction and background A 3-year-old Bosnian girl with a large symptomatic brainstem and multiple supratentorial cavernous angiomas, who underwent neurosurgical treatment, is presented. As multiple cavernomas are more common in familial cases, genetic analyses and neuroradiological imaging were performed in the patient and her parents to see whether there was any evidence for inheritance. This information is important for genetic counseling and provision of medical care for at-risk relatives. Currently, no recommendation is available on how to manage these cases.Results Genetic analyses demonstrated a novel CCM1 frameshift mutation (c.1683_1684insA; p.V562SfsX6) in the child and the asymptomatic 27-year-old mother. Sensitive gradient-echo magnetic resonance imaging of the mother revealed multiple supratentorial lesions, whereas analogous imaging of the father showed no pathological findings.Conclusion This case exemplifies that seemingly sporadic cases with multiple lesions might well be hereditary and that presymptomatic genetic testing of family members may identify relatives for whom clinical and neuroradiological monitoring is indicated. 相似文献
63.
本文从媒介、宿主、传播途径及其遗传学基础对埃立克体传播循环中获得的最新进展进行综述性回顾,为人埃立克体病的预防提供技术支持和基础资料。 相似文献
64.
鼻咽癌在不同高发区人群中的发病差异 总被引:5,自引:0,他引:5
目的:探索在广东省不同鼻咽癌高发区人群中发病差异,探讨相关病因发病因素。方法:1986~1995年对广东省四会市、广州市近6万人前瞻性研究,通过对两地人群鼻咽癌检出率,EBVVCA/IgA阳性率,阳性人群癌前病变,癌变检出率,并以Logistic多元回归分析其差异。结果:发现四会地区人群与广州地区人群相比:①高鼻咽癌检出率;②EBVVCA/IgA阳性人群高合并鼻咽粘膜癌前病变;③EBVVCA/IgA阳性人群高鼻咽癌检出率;④鼻咽粘膜癌前病变高癌变率。结论:EBV感染与肿瘤遗传易感性在鼻咽癌发病上是否起着协同或加强作用值得进一步研究。 相似文献
65.
目的:探讨胃癌微卫星不稳定性(MSI)与胃腺癌中皿管内皮生长因子(VEGF)之间的关系。方法:应用PCR—SSCP技术检测30例胃腺癌5个位点的微卫星不稳定性,同时应用免疫组织化学的方法检测肿瘤皿管内皮生长因子(VEGF)蛋白的表达。结果:MSI阳性率为43.4%(13/30)。VEGF阳性率为60%(18/30)。MSI—H胃癌VEGF的表达显著减少。结论:MSI—H的胃癌与MSS胃癌可能存在两种不同的胃癌及肿瘤血管新生形成的途径。MSI—H肿瘤较低的VEGF表达可能可以解释为何MSI-H胃癌有较低的侵袭性。 相似文献
66.
Arthroscopic shoulder surgery has become a safe tool for evaluation and treatment of a wide range of shoulder problems with few complications. With ever-improving technology (and commitment to motor skill development among arthroscopists), we can expect to maintain this low rate despite increasing procedure complexity. Avoiding complications in arthroscopic shoulder surgery requires careful preoperative planning, judicious patient selection, a thorough understanding of arthroscopic anatomy, and facility with arthroscopic techniques. 相似文献
67.
68.
Axel Stäbler M.D. Richard G. H. Baumeister M.D. Ulrike Szeimies Ulrich Fink M.D. Hermann Berger M.D. 《Skeletal radiology》1994,23(2):103-106
Post-traumatic ulnar carpal translocation is a rare, severe ligamentous injury to the wrist. Radiologic findings include widening of the radiocarpal joint space at the radial styloid process and ulnar displacement of the carpus. Less than 50% of the lunate articulates with the radius in the neutral position; the lunate is tilted dorsally with palmar subluxation due to a ruptured radioscapholunate (RSL) ligament. This malposition should be called rotatory palmar subluxation of the lunate (RPSL), by analogy to rotatory subluxation of the scaphoid (RSS). In contrast to dorsiflexed intercalated segment instability (DISI), in RPSL the RSL ligament is ruptured and, in the majority of cases, the scapholunate ligament remains intact. A prompt diagnosis should lead to successful treatment. 相似文献
69.
LUO Zhengqiang CHEN Anmin GUO Fengjin LI Xinzhi 《中德临床肿瘤学杂志》2006,5(2):138-140
Objective: To investigate the expression of integrin α4 in osteosaxcoma and significance. Methods- Forty-six patients with osteosarcoma (Enneking Ⅰ-Ⅲ) were analyzed for the expression of α4 integrin subunit using immunohistochemical method. Results: Twenty-nine (63.04%) of 46 samples demonstrated positive (+-++) integrin α4 expression. Loss expression of integrin α4 was observed in the patients with advanced Enneking stage (P=0.0040) and with metastatic disease at presentation (P=0.0158). Integrin α4 expression correlated with cell differentiation, the level of malignancy and the invasive behavior of osteosaxcoma. Conclusion: The loss expression of integrin α4 subunit might be a predictor indicating the invasive potential of osteosarcoma and play a role in metastasis of osteosaxcoma patients. 相似文献
70.
L.E. Oostenbrug I.M. Nolte E. Oosterom G. van der Steege G.J. te Meerman H.M. van Dullemen J.P.H. Drenth D.J. de Jong K. van der Linde P.L.M. Jansen J.H. Kleibeuker 《Digestive and liver disease》2006,38(11):834-845
BACKGROUND: Three major polymorphisms of the Caspase-Activation Recruitment Domain containing protein 15 gene have been described to be associated with Crohn's disease. Genotype-phenotype studies reported in literature provide conflicting data on disease localisation and behaviour. We investigated the relation of Caspase-Activation Recruitment Domain containing protein 15 with inflammatory bowel disease and Crohn's disease phenotypic characteristics in a large Dutch cohort and performed a pooled analysis on inflammatory bowel disease patients and Crohn's disease phenotypic characteristics reported in association studies. METHODS: We genotyped 781 cases and 315 controls for the R702W, G908R and 1007fsinsC variants and for six microsatellite markers in and close to Caspase-Activation Recruitment Domain containing protein 15. In the pooled analysis data of 7201 inflammatory bowel disease patients and 3720 controls from 20 studies were included. RESULTS: Association was found for Crohn's disease with R702W and 1007fsinsC, including several disease characteristics, and not for ulcerative colitis. In the pooled analysis all three common Caspase-Activation Recruitment Domain containing protein 15 variants showed strong association with Crohn's disease (p<0.00001; odds ratio varying from 3.0 for single heterozygotes to 14.7 for compound heterozygotes) and not with ulcerative colitis. Phenotype analysis showed association with small bowel involvement, stricturing and penetrating disease. CONCLUSION: Caspase-Activation Recruitment Domain containing protein 15 is associated with Crohn's disease and not with ulcerative colitis. All three common Crohn's disease-associated variants are associated with small bowel involvement, the G908R and 1007fsinsC alleles also being associated with a complicated disease course. 相似文献