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991.
Thirteen female patients with lymphomas involving the genital tract were studied. Their median age was 50 years. There were three cases of stage I disease, one stage II and nine stage IV. The gastrointestinal tract was commonly involved in patients with disease in the ovary. The histology was mostly intermediate or high grade according to the Working Formulation. Immunophenotyping was performed in six patients and they were all B-cell tumours. There appeared to have a strong association between gastrointestinal involvement and ovarian disease. All patients received combination chemotherapy with or without additional radiotherapy and the survival of patients with stage I and II disease appeared to be superior to those with stage IV disease. However, the difference observed did not reach statistical significance because of small patient number. It remains uncertain whether lymphomas of the female genital tract by itself carries a poorer prognosis than the nodal lymphomas of comparable stage and histology. 相似文献
992.
L. Guillou E. Lamoureux S. Masse J. Costa 《Virchows Archiv : an international journal of pathology》1991,418(5):467-471
Summary A case of alveolar soft-part sarcoma located in the uterine corpus is reported. It was an incidental finding in the hysterectomy specimen of a 40-year-old woman. Light and electron microscopic examination revealed periodic-acid-Schiff-positive, diastase-resistant, membrane-bound cytoplasmic granules and crystalloids. Tumour cells expressed immunoreactivity with vimentin, desmin, cytokeratins, NK1/C3 and HMB-45 antibodies. Four years postoperatively, the patient is still alive without evidence of disease. Differential diagnoses, immunocytochemistry and clinical management of uterine alveolar soft-part sarcoma are discussed and the literature reviewed. 相似文献
993.
994.
Angiotensin receptor binding interactions of the angiotensin agonist, 125I-angiotensin II (125I-AII), and antagonist, 125I-[sarcosine1,leucine8]angiotensin II (125I[Sar1,Leu8]AII), are differentially affected by sodium ion concentration. 125I-AII binding to calf cerebellar cortex or adrenal cortex is increased 25 or 2.5 fold respectively when sodium ion concentration is increased from 10 to 150 mM. In brain membranes increasing sodium concentration accelerates the association and slows the dissociation of 125I-AII. 125I[Sar1,Leu8]AII binding to these tissues is much less sensitive to changes in sodium ion concentration. In rabbit uterine homogenates, neither 125I-AII nor 125I[Sar1,Leu8]AII binding is significantly altered by changes in sodium ion concentration. The sodium elicited increase in 125I-AII binding to calf cerebellum is correlated with cationic size and is not an ionic strength effect. The effect of sodium on potencies of angiotensin analogues in competing for 125I[Sar1,Leu8]AII binding does not correlate with agonist or antagonist properties, but is largest for peptides with aspartic acid at position one in the peptide structure. 相似文献
995.
996.
Yassine Nouira Wassime Feki Sami Ben Rhouma Imed Ben Salah Ali Horchani 《International urogynecology journal》2005,16(6):512-514
We report a case of vesicouterine fistula as a complication of forceps delivery revealed by urinary incontinence in a 68-year-old woman. Diagnosis was confirmed by examination and cystography. The treatment was a transperitoneal excision of the fistula. The literature is briefly reviewed and the treatment options are discussed. 相似文献
997.
Immunohistochemical determination of estrogen and progesterone receptor positivity in uterine adenosarcoma 总被引:2,自引:0,他引:2
Amant F Schurmans K Steenkiste E Verbist L Abeler VM Tulunay G De Jonge E Massuger L Moerman P Vergote I 《Gynecologic oncology》2004,93(3):67-685
BACKGROUND: Given the paucity of data regarding hormone dependency, it was the purpose of this study to screen for the presence of estrogen and progesterone receptors in uterine adenosarcoma (UAS). METHODS: One hundred and five centers were asked to screen their files for uterine adenosarcomas. A immunohistochemical estrogen and progesterone receptor determination was performed. RESULTS: Twenty-eight primary UAS were stained, including one cervical adenosarcoma. Sarcomatous overgrowth could be observed in eight. Furthermore, two cases of recurrent UAS, one only consisting of endometrial stromal sarcoma, were stained. UAS lacking sarcomatous overgrowth showed estrogen receptor positivity in 17/20 (85%) and 16/20 (80%) in the epithelial and sarcomatous component, respectively. Progesterone positivity was observed in 13/20 (65%) and 12/20 (60%) in the epithelial and sarcomatous component, respectively. In 18/20 (90%) of the cases, either the estrogen or the progesterone receptor stained positive in the sarcomatous component. UAS with sarcomatous overgrowth showed estrogen receptor positivity in 4/8 (50%) and 0/8 (0%) in the epithelial and sarcomatous component, respectively. Progesterone positivity was observed in 2/8 (25%) and 1/8 (12%) in the epithelial and sarcomatous component, respectively. The stromal component of both recurrent cases stained moderately positive for estrogen receptor whereas progesterone receptor was considered negative. CONCLUSION: The observation that the sarcomatous component of UAS without sarcomatous overgrowth frequently expresses hormone receptors might be of significant clinical importance. 相似文献
998.
子宫动静脉瘘致阴道大出血的临床分析 总被引:21,自引:0,他引:21
目的探讨子宫动静脉瘘致阴道大出血患者的临床特点、诊断与治疗方法以及预后。方法对我院1990年8月至2003年5月收治的15例子宫动静脉瘘患者的临床资料进行回顾性分析。结果本组患者都以异常阴道大量出血就诊,15例均合并剖宫产分娩史、多次刮宫史或妇科恶性肿瘤病史。彩色B超及选择性子宫动脉造影通常可以明确诊断。诊断性刮宫并不能起到有效治疗作用,反而会加重出血。15例患者中,14例接受子宫动脉栓塞术,其中11例(79%)栓塞治疗成功,栓塞术后无并发症发生。保守治疗成功的患者术后均能恢复正常月经,并有5例成功妊娠。结论子宫动静脉瘘是导致阴道大出血的少见却严重的原因之一,子宫动脉栓塞术是治疗子宫动静脉瘘出血有效的保守治疗方法,栓塞术后患者的子宫及卵巢功能并不受影响。 相似文献
999.
目的探讨抑癌基因p16在子宫平滑肌肿瘤发生发展中的作用及其在诊断中的临床意义。方法应用细胞免疫荧光技术及流式细胞术,对55例子宫平滑肌肿瘤石蜡组织块的p16表达定量分析。结果正常子宫平滑肌组织p16表达均为阴性。14例平滑肌瘤仅2例出现过度表达(14%);交界性平滑肌肿瘤12例,多数为过度表达(75%);子宫平滑肌肉瘤29例中,则有27例(93%)出现过度表达。从平滑肌瘤、交界性平滑肌瘤到平滑肌肉瘤,p16表达量显著递增。p16表达量随肿瘤细胞分裂相、异型性、密度的增高也有明显增高。p16低表达者5年生存率为85%,而过度表达者为48%。结论子宫平滑肌肿瘤一旦出现p16过度表达应考虑为恶性;p16表达可能和平滑肌瘤向平滑肌肉瘤的转化密切相关,p16表达可作为判断患者预后的一项客观指标。 相似文献
1000.
经腹超声检测原发性痛经子宫动脉血流动力学研究 总被引:3,自引:0,他引:3
目的:经腹超声(TBUS)检测未婚少女原发性痛经(Primary Dysmenorrhea,PD)子宫动脉血流动力学改变,探讨痛经程度与子宫血流灌注的相关性。方法:54名PD未婚少女和41名正常对照者在月经周期第一天经腹超声检查,记录子宫动脉、弓状动脉、放射动脉、螺旋动脉的搏动指数(PI)与阻力指数(RI),按《中药新药治疗痛经的临床研究指导原则》进行痛经积分和痛经程度判定。结果:中度组、重度组与对照组比较在月经期第一天子宫动脉较细分支血流阻力较高;螺旋动脉的搏动指数、阻力指数与痛经积分具有一定相关性。结论:经腹超声能够检测到未婚少女子宫动脉血流参数;PD月经周期第一天子宫动脉灌注阻力高;PD严重程度与螺旋动脉的搏动指数、阻力指数相关。 相似文献