超关节夹板固定加悬垂石膏治疗肱骨中下段骨折

应用超关节夹板固定加悬垂石膏治疗肱骨中下段骨折２７例。经治疗后随访，Ｘ片复查骨折均在６～８周内愈合。无一例延迟愈合或不愈合。作者认为：夹板固定及石膏塑造同时并用，达到固定和牵引，维持骨折的稳定，消除局部剪力，促进骨愈合的目的。     

Rat middle cerebral artery occlusion by an intraluminal thread compromises collateral blood flow

We compared in Wistar rats collateral blood flow through leptomeningeal anastomoses after middle cerebral artery occlusion using craniotomy (‘extravasal occlusion'), which results in a small volume of cerebral infarction, and after intraluminal thread occlusion (‘intravasal occlusion'), which produces a large volume of cerebral infarction. Simultaneous laser–Doppler flowmetry with two probes placed on the cerebral cortex was used to measure and compare collateral blood flow. Extravasal occlusion caused a cortical blood flow reduction along a gradient in lateral direction, whereas blood flow reduction after intravasal occlusion was more uniformly distributed. It is concluded that permanent intravasal occlusion compromises collateral blood flow and therefore may not be a suitable model for measuring the ability of pharmacotherapeutic agents, if any, to improve collateral blood flow acutely after middle cerebral artery occlusion. The two models can be useful for testing drugs on parenchymal neuroprotective properties. Thereby, the intraluminal technique is preferred because of the possibility to study reperfusion damage when transient occlusion is applied.     

Abnormal glial cytoskeleton in progressive supranuclear palsy

Progressive supranuclear palsy (PSP) is characterized by neurodegenerative changes of the basal ganglia, brainstem and the cerebellum. Moreover, it is noteworthy that abnormal cytoskeleton of glial cells is distributed widely in the brain. The morphological, immunohistochemical and ultrastructural properties of the properties of the peculiar glia have been elucidated. However, many factors remain unsettled regarding the abnormalities. The purpose of this paper is to define the properties of PSP, to present its distributional characteristics, and to examine the correlation of PSP with neuronal loss and astrocytosis.     

埋线提升在中下面部年轻化中的应用与设计

埋线提升是近年来新兴的面部年轻化微创美容技术,其中使用频率高、技术成熟的领域则是用于中下面部年轻化治疗。因此,笔者就这一技术的发展历史、相关面部解剖要点、设计原则及操作要点进行综述,并进一步对该技术现存的问题和展望进行客观评价。     

Lacrimal Duct Occlusion for the Treatment of Dry Eye

The most widespread treatment for dry eyes in clinical practice is an instillation containing artificial tear fluid. When an instillation does not ameliorate dry eye, we use punctal plugs. The insertion of punctal plugs is an eminent curative that positively improves the corneal and conjunctival epithelial disorders and the amount of lacrimal fluid accumulated in the conjunctival sac. We shall introduce the lacrimal duct occlusion utilizing atelocollagen solutions, which solves many of the issues induced by conventional methods.     

肺结核合并肺毛霉菌感染的临床分析

目的探讨肺结核合并肺毛霉菌感染的防治。方法对8例肺结核合并肺毛霉菌感染的危险因素、临床表现、诊断及治疗进行总结分析。结果8例肺结核患者经深部痰培养临床确诊为肺毛霉菌感染。用两性霉素B治疗大约4周后，6例有效，1例出现肾功能不全合并高钾血症行透析治疗，1例合并蛛网膜下腔出血死亡。结论肺毛霉菌病因临床表现无特异性，易误诊。早期诊断，规范抗结核治疗，合理应用抗生素、激素，早期应用两性霉素B脂质体是提高肺结核合并肺毛霉菌病治愈率的关键。     

反支撑形螺纹种植体即刻负载时应力分布的三维有限元分析

目的:利用三维有限元模型,探讨圆柱状反支撑形螺纹种植体螺纹形态变化对周围骨组织应力大小的影响,为临床设计和选择最佳的种植体螺纹参数提供理论依据.方法:利用包含圆柱状反支撑形螺纹种植体的颌骨三维有限元模型,分别设定螺纹宽度恒定(W=0.2)螺纹齿高(H)变化范围为0.2-0.6mm,或螺纹齿高恒定(H=0.4)螺纹宽度(W)范围为0.1-0.4mm.在种植体正中分别加载垂直向100N和颊舌向45°50N的作用力进行分析.观察H和W变化对颌骨平均应力Von-Mises峰值的影响.结果:即刻负载时,垂直向加载(F1)时,齿高及宽度变化时种植体Von-Mises应力峰值增幅分别为68.39％和20.90％;侧向加载(F2)时,种植体应力峰值变化增幅为42.28％和32.51％;结合两种作用力,当螺纹宽度恒定,齿高为0.3-0.5mm时,即刻负载情况下种植体对颌骨产生的应力峰值相对较小;齿高恒定,宽度设计为0.1-0.3mm时,种植体对颌骨产生的应力峰值相对较小.结论:在生物力学方面研究表示,圆柱状反支撑形螺纹种植体最佳的螺纹设计为螺纹齿高在0.3-0.5mm之间,螺纹宽度在0.1-0.3之间;相对于种植体螺纹宽度而言种植体螺纹齿高对应力分布影响更大,种植体螺纹设计时更应重视齿高的设计.     

虚实双挂线治疗复杂性肛瘘71例

目的：探析虚实双挂线治疗复杂性肛瘘效果。方法选择该院2011年6月-2014年6月期间所收治71例复杂性肛瘘患者作为研究对象,分为两组。观察组采取虚实双挂线治疗,对照组采取切开挂线术进行治疗,比较治愈率、复发率及并发症发生率。结果观察组瘘口愈合时间为（15.6±4.4）d,对照组为（18.3±4.7）d,对比差异有统计学意义（t=2.450,P=0.015约0.05）;观察组治愈率、复发率分别为97.2%、2.8%,前者高于对照组,后者低于对照组,对比差异有统计学意义（P<0.05）。观察组并发症发生率为2.8%（1/36）,仅1例漏气,显著低于对照组17.1%（6/35）比较差异有统计学意义（P<0.05）。结论虚实双挂线治疗复杂性肛瘘可最大限度保留患者正常皮肤与肛门结构功能,创口愈合速度更快,治愈率高且不易复发,为理想手术方法。