Chest wall implantation of lung cancer at the drainage tube site: Report of a case

We report herein the case of a 70-year-old man in whom a chest wall implantation of adenocarcinoma of the lung at the drainage tube site was found 4 months after a right lower lobectomy with mediastinal lymph node dissection had been performed for adenocarcinoma of the right lower lobe. The lesion was successfully treated by tumor extirpation. We believe that tumor seeding to the chest wall occurred at the time of thoracotomy. To prevent such tumor seeding, the pleural cavity should be washed out routinely with a massive volume of physiological saline solution prior to closure of the chest wall.     

鼻内镜下腺样体切除术与常规腺样体刮除术的疗效比较

目的:比较鼻内镜下腺样体切除术与常规腺样体刮除术两种术式的疗效。方法:将资料完整的34例腺样体肥大患者分为鼻内镜下腺样体切除术18例(切除术组),常规腺样体刮除术16例(刮除术组);采用声反射鼻测量等参数观察手术疗效,随访6~12个月并进行回顾性分析。结果:切除术组平均手术时间5.25(1.25~15.75)min,刮除术组8.5(1.5~35.0)min,两组差异有统计学意义(P<0.01);切除术组平均出血量50(10~125)ml,刮除术组平均出血量75(5~175)ml,两组比较无统计学意义(P>0.05)。切除术组术后出血1例,刮除术组术后脱水1例。声反射鼻测量计检查鼻咽部最小横截面积,切除术组术前(0.75±0.58)cm2,术后3个月为(1.94±0.63)cm2,术后12个月为(1.99±0.44)cm2;刮除术组术前(0.80±0.51)cm2,术后3个月为(1.83±0.81)cm2,术后12个月(1.89±0.37)cm2。两组手术前后最小横截面积比较差异有统计学意义(均P<0.01),手术前后两组间最小横截面积比较差异均无统计学意义(均P>0.05)。结论:鼻内镜下腺样体切除术具有切除快、出血少等优点。声反射鼻测量计是评估腺样体切除术疗效的客观指标。     

经肛门内镜显微手术切除直肠肿瘤

目的评价经肛门内镜显微手术(TEM)切除直肠绒毛状腺瘤和早期直肠癌的应用效果。方法分析我院总结1995年11月至2001年12月27例TEM手术的临床资料。结果本组患者肿瘤直径中位值2.5cm,肿瘤下缘与齿状线距离(8.9±3.4)cm,肿瘤侵犯直肠周径范围(35.7±17.5)%。平均手术时间(109±46)min。平均住院日4.5d。无围手术期死亡。手术并发症有尿潴留、暂时性大便失禁和慢性阻塞性肺病(COPD)复发。术中2例切穿至腹腔,即刻内镜下修补成功。切缘100%瘤细胞阴性。病理示直肠绒毛状腺瘤14例、直肠腺癌13例,后者包括pTis2例,pT16例和pT25例。直肠癌腔内超声肿瘤T分期符合率为84.6%。5例pT2中2例中转前切除术,1例接受术后放疗,2例无附加任何治疗。平均随访18个月,所有病例无局部复发。死亡2例,但无复发迹象。结论TEM易行且安全,是直肠绒毛状腺瘤和部分T1直肠癌的治愈性手术,也可作为T2直肠癌的姑息性治疗手段。     

Pelvic pain and recurrent urinary incontinence after laparoscopic colposuspension with the endo-stapler

Laparoscopic colposuspension is one of many new operations for treating female urinary stress incontinence. With initially reported success rates similar to those of the traditional open procedure, it appears to combine the advantages of laparoscopy (such as minimal invasiveness and quicker return to normal activities) with the effectiveness of the standard procedure. Different methods and approaches are used, but endoscopic suture techniques remain difficult and time-consuming. The use of endostapling devices for fixation of alloplastic material has been a tempting alternative. We present a case during which laparoscopic colposuspension was performed using staples and mesh. Incontinence did not improve, and the patient suffered severe chronic pain for 18 months postoperatively. Removal of the alloplastic material and traditional abdominal resuspension led to complete cure.     

内镜激光治疗食管和贲门早期表浅癌疗效及DNA和p53表达与预后关系的研究

目的：研究内镜Ｎｄ：ＹＡＧ激光治疗食管和贲门早期表浅癌的远期疗效和ＤＮＡ及ｐ５３表达与预后的关系。方法：对内镜激光治疗癌细胞消失的３２例食管和贲门早期表浅癌病人进行３３～７８个月（平均５５．３个月）的随访。并与１１７例早期食管癌和贲门癌的自然病程对比分析。应用ＰｒｏｄｕｃｔＬｉｍｉｔＥｓｔｉｍａｔｅ方法计算其存活率。应用免疫组化染色法检测ｐ５３表达。应用分光光度计测定癌细胞ＤＮＡ含量。结果：内镜激光治疗５年存活率为９７％，自然病程５年存活率为６７％（Ｐ＜０．０１）。ｐ５３阳性表达和ＤＮＡ非整倍体型病人的复发率分别为７６．９％和６４．３％。结论：内镜Ｎｄ：ＹＡＧ激光是治疗食管和贲门早期表浅癌的有效方法。抗癌基因ｐ５３和ＤＮＡ倍体数与病人的预后有关。     

Two-step endoscopic resection of gastric leiomyomas

Summary Our two-step technique for endoscopic treatment of gastric leiomyomas is illustrated. From January 1979 to June 1991, nine symptomatic patients with sessile leiomyomas of the stomach were treated at the Endoscopy Division of Istituto Nazionale Tumori, Milan.The diagnosis was achieved by means of endoscopic observation of the lesion and, when possible, by ultrasound endoscopy.This new technique consists of first removing superficial portion of the tumor by electrosurgical snare. Second, a cleavage plane is found within the proper muscle layer; the tumor is enucleated as much as possible by tightening the snare around it and creating a pseudo-stalk. No major complication occurred nor were any recurrences observed at 21.8 months in the 7/9 patients treated by endoscopy alone. Endoscopic therapy was performed on an outpatient basis and only large lesions required short hospitalization.     

恶性梗阻性黄疸的外科姑息治疗

不能切除肿瘤的恶性梗阻性黄疸的外科姑息治疗方法繁多，本文介绍自1989年以来，采取开腹经不同途径的带支撑导管胆肠内引流的方法治疗30例，减黄确切，尚对7例高位胆管癌在解除胆道梗阻的基础上行术后(192)Ir和(60)Co联合放疗，提高了病人生存质量及延长了生命。     

Management of abdominal sepsis

Introduction: Today the management of the different forms of peritonitis is generally standardised. The classification of primary and secondary peritonitis is well accepted. From a pathophysiological point of view, postoperative and post-traumatic peritonitis should be considered as independent entities. The bacteriological isolates from the inflamed peritoneal cavity do not correlate with the clinical course, and the occurrence of enterococci and bacteroides may be slightly related to ongoing infectious complications. Classification: Valuable scoring systems mainly rely on systemic signs of the septic disease and seem to better differentiate the prognosis of the disease than more surgically oriented scores do. Although the scoring systems did not allow any clinical decision, they should be used to help better compare patients treated in different institutions. The observation of the minor relevance of bacteriology and the superiority of general sepsis scores agrees with the fact that pre-existing septic organ dysfunction and pre-existing comorbidity are the main determinants of mortality. Treatment: Surgical therapy focuses on the control of the source of infection because it has been clearly shown that, without resolving the source of infection, the prognosis remains poor. Adjuvant surgical measures aim at the further reduction of the bacterial load in the peritoneal cavity. Planned relaparotomy, relaparotomy on demand, and continuous closed peritoneal lavage are used. Results: Clinical results proved these methods to be equally effective although pathophysiological considerations favour closed peritoneal lavage. Conclusion: Summarising the available data, we need a more sophisticated understanding of the pathophysiology of the peritonitis, and well-designed clinical studies are necessary to define the optimal surgical treatment modalities. Received: 27 November 1997     

3种不同创基准备程序性治疗方法在慢性难愈性创面中的效果观察

目的 探讨清创换药、负压引流、富血小板血浆治疗的创基准备程序性治疗在慢性难愈性创面中的效果。方法 回顾性分析2017年5月—2021年5月江南大学附属医院收治的83例创基准备程序性治疗的慢性难愈性创面患者的临床资料,根据治疗方法不同分为清创换药组25例、负压引流组35例、富血小板血浆组23例。比较3组患者创面愈合时间、创面完全愈合患者占比,临床疗效,治疗前后视觉模拟疼痛评分（VAS）差值、温哥华瘢痕评定量表（VSS）评分,治疗前后创面感染指标差值,创面细菌阳性率及复发情况。结果 富血小板血浆组创面愈合时间短于清创换药组和负压引流组（P <0.05）,富血小板血浆组与清创换药组和负压引流组创面完全愈合患者占比比较,差异无统计学意义（P>0.05）;富血小板血浆组与清创换药组和负压引流组总有效率比较,差异无统计学意义（P>0.05）;富血小板血浆组治疗前后VAS评分差值高于清创换药组和负压引流组（P <0.05）,富血小板血浆组VSS评分低于清创换药组和负压引流组（P <0.05）;富血小板血浆组治疗前后C反应蛋白差值、白细胞计数差值均高于清创换药组和负压引流...     

Technique and early clinical results of endoscopic variceal ligation (EVL)

Summary Endoscopic variceal ligation (EVL) is a new technique designed to be used instead of sclerotherapy. Small elastic O rings ligate varices resulting in their strangulation and eradication. During a 12-month period, EVL was employed in 53 consecutive patients, of whom 36 (68%) had alcoholic cirrhosis 17 were Child-Pugh class A, 22 class B, and 14 class C. Varices were graded from I to IV and repeat treatments were given at 1–2 week intervals until the varices were eliminated. At follow-up ranging from 6–18 months (mean 11.5), 217 EVL treatment sessions had been performed. Of the 13 patients (24%) who died during the study, 11 died during the index hospitalization. Active bleeding was controlled in 19 of 21 patients (90%). Of 40 survivors 13 patients (33%) had 1–2 (mean 1.4) recurrent variceal bleeds while 34 patients had repeat EVL treatment. Elimination of distal varices was achieved in 26 and 7 had reduction of varices from grade III–IV to grade I–II or less. Eradication required a mean of 4.4 EVL sessions in Child's A and B patients and 7.0 sessions in Child's C patients (P<0.025). No significant treatment-related complications were observed. EVL appears to control active bleeding, is associated with a low incidence of non-bleeding complications, and may be used as an alternative to sclerotherapy.