足底深支或(和)第一跖背动脉逆行足背岛状皮瓣的临床应用

目的探索足部远端软组织缺损修复的较佳方法。方法采用足底深支或(和)第1跖背动脉逆行足背岛状皮瓣对6例足部远端软组织缺损创面进行修复。结果6例患者均一次性修复,软组织缺损最大面积8cm×6cm,术后随访1~4年,足部功能与外观均较满意。结论足底深支或(和)第1跖背动脉逆行足背岛状皮瓣血管解剖比较恒定,操作简单,是修复足远端软组织缺损的较好方法。     

Thrombotic occlusion of the common carotid artery (CCA) in acute ischemic stroke treated with intravenous tissue plasminogen activator (TPA)

Although common carotid artery (CCA) occlusions are rare, acute clinical presentations vary from mild to devastating strokes primarily due to tandem occlusions in the intracranial arteries. Three patients with acute CCA occlusions were treated with systemic tissue plasminogen activator (TPA). Blood pressures were kept at the upper limits allowed with TPA therapy with fluid balance and the 'head-down' position. Recanalization occurred in intracranial vessels only. Marked early neurological improvement occurred in two of three patients. CCA occlusions should not be considered contra-indication to systemic thrombolysis.     

超声引导下压迫修复冠脉介入术后假性动脉瘤

目的:探讨超声引导下压迫法修复冠脉介入术后假性动脉瘤的可行性和方法。方法:4例冠脉介入术后腹股沟搏动性肿块患者,经彩色多普勒超声确诊股动脉假性动脉瘤,采用实时超声定位及监测下直接压迫法修复股动脉破裂口。结果:3例股动脉假性动脉瘤在超声引导下压迫修复成功,1例失败,未出现并发症。结论:早期超声引导下压迫法结合绷带加压包扎是治疗冠脉介入术后假性动脉瘤的有效方法,简便安全,值得推广。     

大白鼠尾动脉吻合实验的方法与体会

报告了960次大白鼠尾动脉吻合实验,采用端端吻合法800次,即刻通畅率96.5％,套叠吻合法160次,即刻通畅率100％。作者认为利用大白鼠尾动脉作吻合训练,具有节省动物、可多次操作、无需无菌条件、操作简单易行等优点,并介绍了操作方法和注意点。     

胰岛素抵抗和脑血管病关系的研究

目的：探讨胰岛素抵抗与脑梗死、脑出血的关系，为针对胰岛素抵抗的治疗可以有效地预防脑血管疾病提供理论依据。方法：选取42例脑梗死（脑梗死组）、40例脑出血（脑出血组）及30例非脑血管病患者（对照组），分别测定空腹胰岛素（FINS）、空腹血糖（FBG），计算胰岛素敏感指数（ISI），各组间进行比较。结果：脑梗死组和脑出血组患者ISI低于对照组（P〈0.05），而FINS高于对照组（P〈0．05），FBG与对照组差异无统计学意义（P〉0．05）。结论：胰岛素抵抗可能是脑血管病的一个重要危险因素。     

Predictive value of local and core laboratory echocardiographic assessment of cardiac function in patients with chronic stable angina: The ACTION study.

AIMS: To evaluate the relationship between echocardiographic cardiac function and outcome in patients with stable symptomatic angina. METHODS: Baseline echo left ventricular ejection fraction and volume data measured in a central laboratory was available for 7016 patients (92% of the total) participating in the ACTION trial (A Coronary disease Trial Investigating Outcome with Nifedipine GITS). Ejection fraction was also measured by investigators. Evaluation of the different echocardiographic variables was based on adjusted hazard ratios comparing the unfavourable limit of the 90% range of the variable concerned to the favourable limit. RESULTS: The centrally measured ejection fraction was the most powerful predictor of all-cause death (adjusted hazard ratio=2.5), myocardial infarction, any stroke or transient ischaemic attack and overt heart failure (adjusted hazard ratio=4.5). The addition of either end systolic volume or end diastolic volume to ejection fraction did not materially affect the power of prediction. Compared to the central ejection fraction measurement, the investigator-measured ejection fraction was a less powerful predictor for all outcomes considered. CONCLUSION: Routine echocardiography carefully analysed by standardised methods provides useful prognostic information in patients with stable angina, including for total mortality.     

脾动脉起始部真性动脉瘤的手术治疗(附7例报告)

目的：探讨脾动脉起始部真性动脉瘤的手术治疗方法，总结临床治疗经验。方法：回顾性总结1996年1月至2006年8月收治的7例病人，经彩色超声、CT和血管造影检查证实脾动脉起始部真性动脉瘤；均在全身麻醉下行动脉瘤切除，5例行脾动脉血管重建，2例同时行脾脏切除。结果：手术后10—14d治愈出院。随访1—9年，1例人工血管转流术后2年死于急性心肌梗塞，余6例均健康生活。无复发。结论：脾动脉起始部真性动脉瘤切除、脾动脉重建是—种较好的治疗方案。