卵巢室管膜瘤1例CSCD

患者女性,72岁。因查体发现下腹部包块2月余入院。妇科检查：外阴发育正常,阴道通畅,宫颈光滑,触血阴性。子宫扪及不清,盆腔内触及直径约20cm的囊实性包块,固定,无触痛,子宫后壁结节感。三合诊：子宫直肠陷凹扪及结节感,包块固定。     

卵巢室管膜瘤一例

患者女,38岁。反复下腹疼痛伴盆腔包块1年余,于2003年9月入院。妇科检查：子宫如孕40多天大小,右附件区扪及一9cm×8cm×5cm包块,囊实性感,活动,无明显压痛。B超：右附件区肿物8cm×6cm×6cm,中等回声,其中有一直径3．5cm液性暗区,左附件未见异常。临床诊断：右卵巢巧克力囊肿。行右卵巢巧克力囊肿剥除术,术中见：右卵巢5cm×4cm×3cm,其上缘有2．0cm×0．3cm×0．3cm的灰白色细蒂,[第一段]     

脊髓室管膜瘤和星形细胞瘤的MRI影像诊断

目的 探讨脊髓室管膜瘤和星形细胞瘤在MRI上的影像特征,提高其诊断的准确率.方法 回顾性分析经手术病理证实的15例脊髓室管膜瘤和10例星形细胞瘤的临床表现和MRI特征.结果 两者均以T1WI等、低信号,T2WI等、高信号为主.15例脊髓室管膜瘤呈中心性生长,2例可见肿瘤内出血,4例肿瘤内部见囊变,9例肿瘤实质头端或尾端脊髓反应性囊变, 4例肿瘤可见"帽征".10例星形细胞瘤病例中,6例呈偏心性生长,仅1例可见肿瘤内出血,3例肿瘤内部见囊变,4例肿瘤实质头端或尾端脊髓反应性囊变,未见明显"帽征".MRI增强扫描室管膜瘤组12例肿瘤边界清楚,5例肿瘤明显均匀强化,6例可见斑片状或结节状强化.星形细胞瘤组7例病例边界不清,仅2例病灶均匀强化,其余8例均表现为斑片状、点状或环状强化.结论 脊髓室管膜瘤和星形细胞瘤的MRI表现具有一定的特征性,MRI平扫和增强扫描对两者的的诊断和鉴别诊断具有重要价值.     

成年大鼠脑室下区与局灶性脑缺血

脑血管病是人类严重致残和死亡的重要原因,尽管超早期溶栓疗法可挽救脑梗死缺血半暗带的部分神经细胞,但缺血中心区神经细胞的死亡已不可避免。传统的概念认为动物出生后其神经生发(neurogenesis)活动即告停止。到上世纪60年代,Altman等[1]用同位素3H标记的胸腺嘧啶核苷(3H-thy     

雌激素对脑卒中后抑郁大鼠行为学和神经再生的剂量相关性研究

目的探讨雌激素对脑卒中后抑郁(PSD)大鼠行为学和神经元再生的剂量相关性。方法双侧卵巢切除的SD雌性大鼠,应用大脑中动脉栓塞和慢性不可预见温和刺激的方法建立大鼠PSD模型。将大鼠分为对照组和雌激素不同干预剂量(0μg、1μg、10μg、25μg、100μg)组。雌激素持续干预2周后,观察大鼠行为学改变和侧脑室室下区(SVZ)神经元再生的变化。结果雌激素干预2周后,与雌激素0μg组比较,10μg组和25μg组大鼠的行为学数据有明显改善(P0.05)。免疫组化结果显示,与雌激素0μg组比较,10μg组和25μg组SVZ区神经元数增加明显(分别为P0.01,P0.05)。结论适度生理剂量雌激素可通过增加SVZ神经元改善PSD大鼠的抑郁状态。     

83例颅内室管膜肿瘤临床分析

目的 总结颅内室管膜肿瘤的临床特点,探讨其预后相关因素.方法 回顾性总结83例颅内室管膜肿瘤的分布、年龄、病理及影像学特点,分析其手术治疗及辅助治疗的效果.结果 83例颅内室管膜肿瘤中幕下室管膜肿瘤41例,幕上室管膜肿瘤42例.年龄≤15岁37例,＞15岁46例.病理按WHO肿瘤组织学分级:Ⅰ～Ⅱ级58例(69.9%),Ⅲ级25例(30.1%).手术全切67例(80.7%),次全切16例(19.3%).5年存活率81.9%(68/83).手术切除程度和病理分级是影响颅内室管膜肿瘤患者预后的高危因素.结论 肿瘤全切可明显改善患者的预后.术后发现肿瘤残留,适.合者可考虑二次手术切除.间变性室管膜瘤预后较差.放疗在颅内室管膜肿瘤的治疗中具有重要作用,化疗作用有限,主要尝试用于婴幼儿以避免放疗的副损害.

Abstract：

Objective To study the clinical features of patients with intracranial ependymal tumour, and explore the prognostic factors which have.a significant association with the outcome. Methods Eighty-three patients with histologically proven ependymal tumour were retrospectively reviewed. The tumour location, the patients' age, the histological features, imaging characteristics, surgical management and adjuvant therapy were studied. Results In 83 cases of intracranial ependymal tumour,41 cases were infratentorial and 42 cases were supratentorial ependymal tumour, 37 patients age ≤15 years, while 46patients age ＞ 15 years. Fifty-eight patients ( 69.9% ) and 25 patients (30.1% ) had low (WHO Ⅰ - Ⅱ ) and high-grade (WHOⅢ) tumors respectively. Sixty-reven (80.7%) patients had gross total resection and 16patients ( 19.3% ) had subtotal resection. The 5-year survival rate was 81.9%( 68/83 ). The factors that were found to have a statistical significance association with the outcome were the extent of the resection and the pathologic characteristics. Conclusions Gross total resection of these tumors results in a good long-term outcome. Reoperation should be considered, if feasible, to remove residual malignant tissue. Anaplastic ependymomas carries a much poorer prognosis. Radiotherapy may play an important role in their treatment.The role of chemotherapy appears limited but can be attempted, especially in the very young, in order to avoid the deleterious effect of radiotherapy.     

脑室系统外室管膜瘤7例分析

脑室系统外室管膜瘤是起源于脑内白质室管膜细胞巢的特殊类型颅内室管膜瘤,具有较高的全切除率、低复发率和良好的长期生存率.本文就我院最近几年内经手术病理证实的脑室系统外室管膜瘤7例的临床表现和治疗预后进行探讨.     

32例早产儿室管膜下出血的B超与临床分析

我院新生儿病房自2004年1月至2006年3月对所收治的201例早产儿于生后2～3天进行头颅彩超常规检查，经头颅彩超证实32例为室管膜下出血（SHE），现将有关资料分析如下。