Clinical efficacy of Qili Qiangxin Capsule combined with exercise rehabilitation in the treatment of chronic heart failure

ObjectiveTo investigate the effect of Qili Qiangxin Capsule combined with cardiac exercise rehabilitation on patients with chronic heart failure (CHF).MethodsA total of 93 CHF patients admitted to Shanghai's Putuo District Central Hospital from March 2021 to December 2021 were included in the study and were randomly divided into the control group (46 cases) and the intervention group (47 cases). The control group received routine treatment, and the intervention group was treated with Qili Qiangxin Capsule as well as cardiac exercise rehabilitation that was routine for patients with CHF. The total effective rate, 6-min walking distance, left ventricular ejection fraction, B-type natriuretic peptide (BNP) level, left ventricular end-systolic diameter, and left ventricular end-diastolic diameter were compared in terms of the two groups.ResultsAfter three months of treatment, when compared with the control group, the total effective rate of the treatment on the patients in the intervention group increased significantly (87.23% vs 63.04%; P < 0.05). The 6-minute walking distance, BNP level, and the left ventricular end-diastolic diameter improved more drastically in the intervention group than in the control group, and the differences were statistically significant (P < 0.05). There was no significant difference in the other indicators before and after treatment (P > 0.05).ConclusionQili Qiangxin Capsule combined with cardiac exercise rehabilitation can significantly improve cardiac and motor function in patients with CHF.     

督灸联合走罐治疗过敏性鼻炎28例（英文）

目的:观察督灸联合走罐治疗过敏性鼻炎的临床疗效。方法:选取符合纳入标准的28例过敏性鼻炎患者。先于患者背部行走罐治疗,然后行督灸治疗,治疗6次后对患者症状、体征变化情况进行疗效评定。结果:显效14例,有效12例,无效2例,总有效率达92.86%。结论:督灸联合走罐疗法可有效治疗过敏性鼻炎,值得临床借鉴。     

针刺对围绝经期失眠患者内分泌轴的影响:病例系列研究（英文）

目的:探究针刺对围绝经期失眠患者的临床疗效及其对下丘脑-垂体-肾上腺轴(HPA)以及下丘脑-垂体-卵巢轴(HPOA)的影响。方法:对42例围绝经期失眠患者行针刺治疗,针刺时患者取俯卧位,穴位选取百会、四神聪、风府、安眠、神道、肝俞、脾俞、肾俞、神门、三阴交,隔日针灸一次,每周三次,每次留针30 min,共治疗4周。于治疗前后分别评估患者匹兹堡睡眠质量指数(PSQI)评分,HPA相关指标及HPOA相关指标。结果:治疗后患者PSQI评分低于治疗前,各分项评分如主观睡眠质量、入睡潜伏期、睡眠持续性、习惯性睡眠效率、睡眠紊乱、催眠药物使用、日间功能紊乱评分均低于治疗前,HPA相关激素指标均较前下降,HPOA相关激素指标均较前下降,E₂较前升高,以上结果均具有统计学意义(all P<0.05)。结论:针刺能改善围绝经期失眠患者的临床症状及激素指标,安全性高,值得临床推广应用。     

针刺治疗癌症相关症状临床研究的文献计量学分析（英文）

Background:Acupuncture has been recommended as a nonpharmacological intervention for managing cancer-related symptoms.However,there are few bibliometric analysis-based studies concerning the overall trends and characteristics in acupuncture therapy for cancer management.This study aims to summarize the status and bibliometric characteristics of acupuncture as an intervention for cancer-related symptoms.Methods:All clinical research papers on acupuncture for the management of cancer-related sympt...     

散结止痛凝胶膏对乳腺增生模型大鼠的影响

目的 研究散结止痛凝胶膏对乳腺增生模型大鼠的治疗作用,并探讨其作用机制。方法 采用肌注苯甲酸雌二醇及黄体酮建立大鼠乳腺增生模型,造模成功后,给药30 d,观察大鼠乳头形态变化,用放射免疫法测定大鼠血清性激素水平,并取乳腺组织做病理切片,观察组织病理学改变。结果 散结止痛凝胶膏能明显减小乳腺增生模型大鼠乳头高度,显著降低血清雌二醇水平,升高孕酮水平。病理组织学检查结果提示凝胶膏可显著减少乳腺增生小叶和腺泡的数量,改善导管上皮增生程度,抑制腺腔和导管腔分泌现象。结论 散结止痛凝胶膏对大鼠乳腺增生病有良好的治疗作用,能够有效调整大鼠体内性激素水平。     

仙鹤草的抗肿瘤作用机制及临床应用综述

仙鹤草（Agrimonia pilosa）是中国延用两千多年的传统中药材之一,因其具有诸多药理作用而在临床广泛应用于肿瘤等多种疾病。恶性肿瘤是一类严重危害人类健康的疾病,中草药可为综合治疗提供思路。近年来,仙鹤草的抗肿瘤作用得到了医务工作者及科研工作者较多的重视和研究。本文通过实验研究、临床研究和经验总结的文献整理,综述仙鹤草在抗肿瘤方面的作用机制,提示其有诱导肿瘤细胞周期阻滞,诱导肿瘤细胞凋亡,增强对肿瘤细胞免疫的抗肿瘤机制。在临床应用仙鹤草辅助抗肿瘤治疗时,可根据仙鹤草的作用机制及前人经验总结合理使用,充分发挥其扶正、抗肿瘤作用。     

范炳华教授治疗椎源性脏腑病经验举隅

[目的]探讨范炳华教授治疗椎源性脏腑病的临床经验。[方法]围绕范炳华教授的临床指导和病案学习,对范炳华教授临床辨证论治椎源性脏腑病的理论、学术思想及具体方法进行整理与分析,并举隅三个案例予以佐证,观察实际治疗效果。[结果]范炳华教授在诊疗脊柱相关疾病过程中,提出"症因相关"理论,推崇"有症必有因,症因须相关,治因宜为先"的学术思想。初诊时,注重从体征表现及临床症状着手治疗椎源性脏腑病,采用触诊之法寻出体征及症状与内在病因的相关性,经过综合性辨证,排除需要鉴别的类似病症,针对实际内因给予准确论治。所列举三例病案精准治疗后,具有明显临床效果。[结论]范炳华教授总结的"审证三原则"学术思想具有很高的现实指导意义,针对椎源性脏腑病的临床诊治,有很强的可操作性和实用性,值得实际临证借鉴和推广。     

Rupture of ovarian endometriotic cyst complicated with endometriosis: A case report

BACKGROUNDEndometriosis (EMs), an estrogen-dependent disease, refers to the appearance of mucosa-covered endometrial tissues (glandular and interstitial) growing in the uterine cavity outside the uterine myometrium. It is commonly seen in women aged 25 to 45, with an incidence of approximately 10%-15%.CASE SUMMARYA 35-year-old unmarried female who denied a history of sex with an intact hymen had multiple dysmenorrhea and pain in the left lower abdomen that recurred during menstruation. Ultrasound examination revealed a dark cystic area measuring 4.9 cm × 4.6 cm on the left side with poor light transmittance, which suggested a left endometriotic cyst. The patient was treated with pain medications (four capsules t.i.d., p.o.). After one month, computed tomography of the abdomen and pelvis revealed a low-density focus measuring approximately 38 mm in diameter, a blurred mesentery fat plane in the pelvic cavity, and pelvic effusion. Ultrasound showed a complex echo density measuring 5.2 cm × 3.0 cm × 4.2 cm in the left ovarian area and a fluid sonolucent area with a depth of 2.0 cm in the pelvic cavity. Left ovarian cystectomy, electrocautery for endometriotic lesions, myomectomy, and pelvic adhesion lysis were performed under laparoscopy. The postoperative diagnosis was left ovarian chocolate cyst rupture and EMs (stage III, ovarian type, peritoneal type).CONCLUSIONLaparoscopic surgery can safely control the symptoms of EMs and effectively eradicate the disease.     

Preoperative pain sensitivity predicts postoperative pain severity and analgesics requirement in lumbar fusion surgery – a prospective observational study

BACKGROUND CONTENTThe goal of postoperative pain management is to facilitate the patient's return to normal activity and decrease the detrimental effects of acute postsurgical pain. In order to provide more tailored and successful pain treatment, it is necessary to identify individuals who are at a high risk of experiencing severe postoperative pain. The most precise way to assess pain sensitivity is by determining the pressure pain threshold and heat pain threshold by objective methods using a digital algometer and neurotouch respectively.PURPOSEThe primary aim of the study is to assess the preoperative pain threshold and its influence on postoperative pain severity and analgesics requirements in patients undergoing lumbar fusion surgeries.STUDY DESIGNProspective, observational study.PATIENT SAMPLESixty patients requiring a single-level lumbar fusion surgery.OUTCOME MEASURESPostoperative pain intensity and the amount of postoperative analgesics consumption.METHODSIn our patients, preoperative pain sensitivity was assessed by pressure pain threshold measurements with the help of a digital algometer, and heat pain threshold using a neurotouch instrument. In addition, pain sensitivity questionnaires (PSQ) were used in all our patients to determine pain sensitivity. Preoperative psychosocial and functional assessments were performed by Hospital anxiety-depression scores (HADS), and Oswestry disability index (ODI) respectively. Preoperative visual analog scale (VAS) score was determined at three instances of needle prick (phlebotomy, glucometer blood sugar, and intradermal antibiotic test dose) and during the range of movements of the lumbar spine region. Postoperative VAS score and postoperative breakthrough analgesic requirements were recorded in all of these patients from day 0 to day 3.RESULTSThe average age of the patients was 51.11±13.467 years and 70% were females. Females had lower mean algometry values (72.14±7.56) compared to males (77.34±6.33). Patients with higher HADS (p<.0016), higher PSQ (p<.001), higher ODI scores(p<.001), and female gender significantly correlated with a lower algometer average indicating high pain sensitivity. Patients with lower preoperative VAS scores and with higher neurotouch scores showed lower postoperative VAS scores at different time periods. Preoperative VAS scores, algometer average scores, neurotouch scores, and HADS scores were considered as independent variables (predictors) for postoperative VAS at 6 hours period. By the multivariate analysis, factors like preoperative VAS scores, algometer average scores, and HADS scores were statistically significant (p<.05). There was a significant correlation between algometer average scores (p<.001) with the breakthrough analgesics.CONCLUSIONPreoperative assessment of pain sensitivity can predict postoperative analgesic requirements and aid in recovery. Patients with a lower pain threshold should be counseled preoperatively and also receive a better titration of analgesics perioperatively.     

Electroacupuncture treatment of benign prostatic hyperplasia: A case report

Benign prostatic hyperplasia (BPH) is characterized by symptoms such as frequent urination and difficulty in urination. Currently, treatment is mainly carried out using medications and surgery, but all of these methods can lead to certain adverse effects. In this case, a ninety-year-old male elderly patient came to our acupuncture clinic for treatment of urinary tract occlusion due to BPH. According to the patient's condition, we adopted the eletroacupuncture treatment protocol of Prof. Zhanglian Wang, a famous experienced Chinese medicine doctor. After six weeks of acupuncture treatment, the patient's urinary status improved significantly. This case suggests that acupuncture may be an effective complementary alternative therapy for BPH.