全文获取类型
收费全文 | 601篇 |
免费 | 51篇 |
国内免费 | 2篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 18篇 |
妇产科学 | 8篇 |
基础医学 | 53篇 |
口腔科学 | 9篇 |
临床医学 | 79篇 |
内科学 | 133篇 |
皮肤病学 | 20篇 |
神经病学 | 30篇 |
特种医学 | 13篇 |
外科学 | 89篇 |
综合类 | 10篇 |
一般理论 | 9篇 |
预防医学 | 78篇 |
眼科学 | 33篇 |
药学 | 32篇 |
中国医学 | 7篇 |
肿瘤学 | 30篇 |
出版年
2024年 | 2篇 |
2023年 | 20篇 |
2022年 | 9篇 |
2021年 | 54篇 |
2020年 | 42篇 |
2019年 | 34篇 |
2018年 | 46篇 |
2017年 | 24篇 |
2016年 | 29篇 |
2015年 | 37篇 |
2014年 | 34篇 |
2013年 | 41篇 |
2012年 | 52篇 |
2011年 | 51篇 |
2010年 | 25篇 |
2009年 | 10篇 |
2008年 | 31篇 |
2007年 | 29篇 |
2006年 | 27篇 |
2005年 | 20篇 |
2004年 | 16篇 |
2003年 | 8篇 |
2002年 | 4篇 |
2001年 | 1篇 |
2000年 | 1篇 |
1999年 | 1篇 |
1998年 | 3篇 |
1996年 | 2篇 |
1994年 | 1篇 |
排序方式: 共有654条查询结果,搜索用时 250 毫秒
21.
22.
Mohammad Golriz Saroa El Sakka Ali Majlesara Arman Edalatpour Mohammadreza Hafezi Nahid Rezaei Camelia Garoussi Jalal Arwin Arash Saffari Hanna Raisi Arezou Abbasi Arianeb Mehrabi 《Journal of gastrointestinal surgery》2016,20(3):587-594
Aim
Extended liver resection has increased during the last decades. However, hepatic hemodynamic changes after resection and the consequent complications like post hepatectomy liver failure are still a challenging issue. The aim of this study was to systematically evaluate the role of stepwise liver resection on hepatic hemodynamic changes.Methods
To evaluate this effect we performed 25, 50, and 75 % sequential liver resections in 10 pigs. Before and after each resection, the hepatic artery flow and portal vein flow in relation to the remnant liver volume (RLV) as well as hepatic vascular pressures were measured and compared between the groups.Results
Following sequential liver resection, the hepatic artery flow /100 g decreases and the portal vein flow increases up to 17 and 167 % following extended liver resection (75 %), respectively. Also, during stepwise liver resection, the portal vein pressure increases gradually up to 33 % following extended hepatectomy (75 %).Conclusion
Sequential decrease in the RLV decreases the hepatic artery flow /100 g and increases the portal vein flow /100 g and portal vein pressure. As the consequence, the liver goes under more poor-oxygenated blood supply and higher pressure. This may be one of the most important mechanisms of the post hepatectomy liver failure in case of extended liver resection.23.
Mohammadreza Hojat Jennifer DeSantis Stephen C. Shannon Luke H. Mortensen Mark R. Speicher Lynn Bragan Marianna LaNoue Leonard H. Calabrese 《Advances in health sciences education : theory and practice》2018,23(5):899-920
The Jefferson Scale of Empathy (JSE) is a broadly used instrument developed to measure empathy in the context of health professions education and patient care. Evidence in support of psychometrics of the JSE has been reported in health professions students and practitioners with the exception of osteopathic medical students. This study was designed to examine measurement properties, underlying components, and latent variable structure of the JSE in a nationwide sample of first-year matriculants at U.S. colleges of osteopathic medicine, and to develop a national norm table for the assessment of JSE scores. A web-based survey was administered at the beginning of the 2017–2018 academic year which included the JSE, a scale to detect “good impression” responses, and demographic/background information. Usable surveys were received from 6009 students enrolled in 41 college campuses (median response rate?=?92%). The JSE mean score and standard deviation for the sample were 116.54 and 10.85, respectively. Item-total score correlations were positive and statistically significant (p?<?0.01), and Cronbach α?=?0.82. Significant gender differences were observed on the JSE scores in favor of women. Also, significant differences were found on item scores between top and bottom third scorers on the JSE. Three factors of Perspective Taking, Compassionate Care, and Walking in Patient’s Shoes emerged in an exploratory factor analysis by using half of the sample. Results of confirmatory factor analysis with another half of the sample confirmed the 3-factor model. We also developed a national norm table which is the first to assess students’ JSE scores against national data. 相似文献
24.
Mohammadreza Alizadeh-Ghodsi Ali Zavvari Mohammad Reza Shiri-Shahsavar 《Nutritional neuroscience》2018,21(2):92-96
Multiple sclerosis (MS) is a disease which manifests demyelination of neuronal cells in the brain. Despite extensive research on the mechanisms of disease development and progression, the exact mechanism is not elucidated yet, which has hampered drug development and subsequent treatment of the disease. We have recently shown that the serum levels of arsenic and malondialdehyde, a lipid peroxidation marker, are high in MS patients. In this article, we would like to formulate the hypothesis that arsenic may cause MS by induction of inflammation, degeneration, and apoptosis in neuronal cells. The induction of ROS generation in cells upon exposure to arsenic as a heavy metal may be involved in the pathogenesis of MS. Tau protein, a member of the family of microtubule-associated proteins, is mainly expressed in neurons and contribute to the assembly of neuronal microtubules network. Arsenic may affect the hyperphosphorylation and aggregation of tau proteins and may be involved in the cascade leading to deregulation of tau function associated with neurodegeneration. For validation of this hypothesis, studies might be conducted to evaluate the association of arsenic levels and tau protein levels in MS patients. Further studies might also focus on the trafficking along microtubules in neurons of MS patient with regard to hyperphosphorylation of tau protein. This hypothesis may add a new dimension to the understanding of MS etiology and help to design novel therapeutic agents against potential targets that might be discovered. If this hypothesis proves to be true, tau phosphorylation inhibitors can be potential candidates for MS drug development. 相似文献
25.
Mohammadreza Hojat 《Medical education》2018,52(4):456-457
26.
27.
28.
29.
Sanaz Jamshidi Yousef Moradi Ghazaleh Nameni Mohammad Ali Mohsenpour Mohammadreza Vafa 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2021,15(2):605-613
Background and aimsPresent meta-analysis and systematic review was conducted to synthesis a definitive conclusion from previous randomized controlled clinical trials (RCTs).MethodsA comprehensive search was done up to July 2020, in order to extract RCTs which investigated the effect of cashew nut on weight, body mass index (BMI), waist circumference (WC), fasting blood sugar (FBS), insulin, and Homeostatic Model Assessment for Insulin Resistance (HOMA-IR). Weighted mean difference (WMD) and 95% confidence interval (CI) were used to estimate effect size. Meta regression analysis was done to identify probable sources of heterogeneity.ResultsSix clinical trials with 521 participants were included. Combined effect sizes demonstrated no effect of cashew consumption on weight (WMD): 0.02, 95% CI: ?1.04, 1.09, P > 0.05), BMI (WMD: 0.1, 95% CI: ?0.72, 0.74, P > 0.05), and WC (WMD: ?0.13, 95% CI: ?1.97, 1.70, P > 0.05). Results were also not significant for FBS (WMD: 3.58, 95% CI: ?3.92, 11.08, P > 0.05), insulin (WMD: ?0.19, 95% CI: ?1.63, 1.25, P > 0.05), and HOMA-IR (WMD: 0.25, 95% CI: ?0.55, 1.06, P > 0.05).ConclusionThe sum up, incorporating cashew into the diet has no significant effect on body composition or modifying glycemic indices. 相似文献
30.