3487例胃病患者Hp抗体的临床观察

３４８７例胃病患者Ｈｐ抗体的临床观察附属第一医院内科胡滨，泮娇云，韩清锡，林秀英［关键词］幽门螺杆菌，十二指肠球部溃疡，胃溃疡，慢性萎缩性胃炎伴肠化，胃癌１９８３年Ｍａｒｓｈａｌｌ和Ｗａｒｒｅｎ（１）首次从慢性胃病患者胃粘膜中成功地分离出幽门螺杆菌（...     

脂氧素A4对心肌缺血再灌注损伤的保护作用

Objective To investigate the roles of lipoxin A4, an endegenous lipid mediator with wide anti-inflammatory fea- tures, in attenuating myocardial ischemia-reperfusion injury and the possible mechanisms. Methods Thirty male KM mice were divid- ed randomly into three groups, 10 in each: ischemia-reperfusion group (group A), lipoxin A4 (0.1 mg/kg) group (group B) and Zn- PP (Zinc protoporphyrin Ⅸ, 25 mg/kg)phus lipoxin A4 (0.1 mg/kg)group (group C). A ischemia-reperfusion heart model was de- veloped by ligating the lift anterior descending branch of the coronary artery. A dine of 10% dehydrated alcohol in 0.2 ml for group A, a dose of isochoric lipoxin A4 for group B and a dose of isochoric ZnPP + lipoxin A4 for group C was infused into the ascending aorta through a catheter, which was kpassing the right common carotid artery, 30 minutes after reperfusion. The concentration of serum TNF-α, activities of serum crestine kinase(CK) and lactate dehydrogenase (LDH), activities of myeloperoxidase (MPO) and malond- ialdehyde (MDA) and the cell apoptosis rate in the myocardial tissue were measured 5 hours after reperfusion. Pathological features of the inflammatory infiltration in the myocardium were also observated.Results As compared with group A, the inflammatoryry infiltra- tion in the ischemic and necrotic regions tithe myocardium was reduced, with group C in the intermediate range. The serum activities of CK and LDH wine significantly lower in group B and C than that in group A, and the lowest activities were detected in group B. Similar findings were observed for MPO, an indicator for neutrophil infiltration, and MDA, an indictor for cell injury caused by oxy- gen radicals, in the myocardium. The concentration of TNF-α and the rate of cadiocyte apoptosis were decreased significantly in group B(P < 0.01). ZnPP, an inhibitor of heine oxygenase (HO)-1, attenusted the above protective effects of lipoxin A4 significantly (P<0.05). Conclusion Lipoxin A4 has protective effects against myocardial ischemia-reperfusion injury, and HO-1 may have a potential role in the protectve mechanisms of lipoxin A4, probably pertly by means of reducing the production of reactive oxygen spe- cies and TNF-α, decreasing the activation and infiltration of neutrophils, alleviating inflammatory damage and avoiding apoptosis.     

带塑料插入件栓式附着体义齿修复后满意度的调查

目的 通过问卷调查表对患者戴用附着体义齿后的主观感受进行研究.方法 选择上下牙列缺损患者42例,共制作带塑料插入件栓式附着体义齿47例,于戴牙后1个月,患者基本适应戴用义齿,通过问卷调查,了解患者戴用义齿后的适应情况、对义齿的满意程度及咀嚼功能的变化等.结果 患者对带塑料插入件栓式附着体义齿和传统可摘局部义齿两种修复方式比较,在总的满意度、美观、舒适、咀嚼、语言、适应期、食物结构改变等方面,前者明显优于后者,差异有统计学意义.结论 带塑料插入件栓式附着体义齿在美观及功能上不仅能满足患者的要求,而且远优于传统可摘局部义齿.     

有关中医方面健康教育在我区的开展

目的：介绍有关中医方面健康教育在我病区的开展。方法：通过从内容、形式两方面介绍有关中医方面健康教育在我病区的开展。结果：有关中医方面健康教育可弥补患者在这方面知识的不足，深受患者及家属的欢迎。     

经皮顺行交锁钉治疗股骨干骨折

目的:评价经皮顺行交锁钉治疗股骨干骨折的临床疗效.方法:对79例82处股骨干骨折采用髋部小切口经皮顺行交锁钉治疗,观察疗效.结果:75例(92%)获得了良好的解剖对位并达到一期愈合,6例(8%)迟缓愈合.另外,由于再次手术1例(1%)发生了深部感染.失血量较少(平均小于100 mL),切口平均长25 mm.1年后随访只有10%髋部疼痛.结论:与传统手术方式相比,经皮技术术中出血少、对周围组织创伤少,是一个安全又有效的方法.     

咪唑安定清醒镇静用于纤支镜检的护理配合

目的 为了减轻患者镜检时的痛苦和恐惧感。方法对80例拟行纤支镜患者于检查前分别缓慢静脉注射度冷丁50mg 咪唑安定0．06mg／kg。同时做好术前准备：禁食，建立静脉通路，吸氧，严密观察注药后的呼吸变化；术中严密监测及详细记录呼吸、心率、氧饱和度、血压的变化；术后特别交待病人不能自己开车，由家属陪伴回家或返病房。结论咪唑安定清醒镇静用于纤支镜检能安全有效地起到镇静作用。     

长脉宽Nd:YAG 1 064nm激光治疗化脓性肉芽肿疗效观察

化脓性肉芽肿（Pyogenic Granuloma，PG）又称毛细血管扩张性肉芽肿（Granuloma Telangiectaticum），是一种后天性、良性结节状增生，为无菌性肉芽肿，好发于面部、头皮、手、足等部位。传统的治疗方法有手术，CO2激光、铜蒸汽激光、VP532激光等单独或联合治疗以及微波、电离、冷冻等方法。治疗原理多基于组织凝固或气化，疗效肯定，但治疗术中出血量大、治疗时间长且有组织损伤，部分患者可出现瘢痕。2005年7月-2006年6月，我们采用无创性长脉宽Nd：YAG1064nm激光治疗化脓性肉芽肿27例，取得了良好疗效。     

腹膜透析液中加入复方氨基酸液对改善腹膜的超滤作用

我院在腹膜透析液中加入复方氨基酸液改善患者的超滤，效果良好，报告如下。     

防止心肌梗塞再发作的护理要点

护士的重要作用是使心肌梗塞(MI)患者自己认识到MI危险因素,引起其注意并加以防治,以防止MI的再发生。危险因素可以由饮食生活的改变得到一时的改善;不过长期坚持却比较困难。作者对Ⅱ期的心脏康复按一定的期间作集体或个别的指导,对于门诊来院接受指导的52例MI患者(平均60岁)的危险因素,作了3年的追踪调查。结果表明,改善危险因素,可以防止MI患者的再发作。精神紧张尽管也是危险因素之一,但由于没有评价的标准,所以取消了对这一因素的追踪调查。危险因素的组合     

多媒体在"尼可刹米对呼吸抑制的解救"实验课中应用的体会

多媒体计算机用于药理实验课教学，以其直观性强、图形描记连续性好、操作方便、重复运行成本低、可剪裁编辑、易复制保存、能反复回放以及供学生随时上校园网查阅等特点深受师生们的欢迎。介绍了在“尼可刹米对呼吸抑制的解救”实验课中应用多媒体计算机的一些方法和体会。