温热式低周波配合温泉及矿泥疗法综合治疗神经根型颈椎病疗效观察

颈椎病以神经根型发病率最高[1] ,我们采用温热式低周波配合汤岗子温泉及矿泥疗法治疗神经根型颈椎病 60例 ,取得了较好疗效 ,报道如下。一、资料与方法患者 12 0例 ,均依据《康复医学诊疗规范》中神经根型颈椎病诊断标准确诊[2 ] ,其中男 76例 ,女 44例 ;年龄 2 8～ 70岁 ,平均 5 3 .5岁 ;病程 0 .6～ 8.0年 ,平均 3 .2年。全部病例随机分为2组 ,治疗组 60例 ,其中男 3 9例 ,女 2 1例 ;年龄 2 8～ 70岁 ,平均5 4.8岁 ;病程 0 .6～ 8.0年 ;采用温热式低周波、汤岗子矿泉水及矿泥疗法。对照组 60例 ,其中男 3 7例 ,女 2 3例 ;年龄 2 9～ 68岁…     

桂枝茯苓十八味汤治疗卵巢囊肿57例

笔者应用桂枝茯苓十八昧汤治疗卵巢囊肿,疗效满意,现报告如下. 1 临床资料 1.1 一般资料:本资料共57例,均系内蒙古包头市东河区中医院2009年6～12月份门诊病人;年龄最小者27岁,最大者46岁,27～37岁20例,38～46岁37例.     

B超在214例胆系痰症，结石诊断中的评价

对术前B超诊断胆系炎症，结石214例与手术，病理结果进行对照分析，手术符合率为91．6％，假阳性8例，假阴性10例，讨论了B超在胆系炎症，结石诊断中的价值及其限度，并提出了假阳性及假阴性图象的识别与分析。     

住院精神病人8年临床资料分析

目的了解我院住院精神病人的临床特点,为精神卫生防治提供科学依据。方法采用回顾性调查方法,对8年出院的病历资料进行调查,并与我市相同年份的GDP进行相关分析。结果女性多于男性,农村人口占多数(69.24%),初中及以下文化程度偏多73.57%,婚姻状态较差。各种诱因导致精神障碍发生率为(33.83%)。精神分裂症占首位(50.34%),神经症占第2位(11.36%),情感性精神障碍占第3位(10.48%)。治疗单一用药占(64.96%),抗精神病药物使用频度最高的是氯氮平(20.07%),其次利培酮(18.70%);抗抑郁药物使用频度最高的是帕罗西汀(9.90%),其次米氮平(3.66%),好转率(85.01%)。我市人均GDP与住院各类精神病人数之间成正相关。结论随着时代的发展,我市住院精神病人数有增加趋势,尤其是神经症病人数增加明显,提示加强心理卫生工作非常必要。     

雕刻—拼接法制作自体肋软骨耳支架

目的探索一种自体肋软骨耳支架的雕刻—拼接制作方法,以期获得良好的再造耳形态。方法 2011年1月至2012年1月,共行545侧外耳再造术。应用改良Nagata法耳再造术285例,扩张皮瓣法260例。切取第6~8肋软骨,分2~3层雕刻、拼接耳支架,构建耳轮、对耳轮、耳舟、三角窝、对耳轮上脚、耳屏、对耳屏、耳甲腔等耳廓亚结构,用于外耳再造术。结果术后有6例因局部皮肤坏死致耳支架外露,经再次手术处理后愈合;1例因感染取出肋软骨支架,6个月后再次行外耳再造术。本组患者术后随访6~12个月,488例再造耳廓形态良好,效果满意;80例再造耳廓亚结构欠清晰,效果欠佳;另有19例失访。结论用雕刻—拼接法制作自体肋软骨耳支架,可获得结构稳固、形态逼真的支架,是耳再造获得良好效果的必要步骤。     

损伤皮肤修复和伤口愈合过程中的干细胞：问题与前景

BACKGROUND:Present treatments for chronic skin wounds have certain limitations, and adult stem cells play a potential part in cutaneous repair and regeneration. OBJECTIVE:To review effects of stem cells in skin regeneration and wound healing. METHODS:The first author retrieved CNKI and Medline databases by computer for relevant articles published from 2000 to 2010. The keywords were “epidermal stem cells, hair follicle stem cells, stem cells, transplantation, dermal stem cells” in Chinese and in English, respectively. Then totally 489 papers were obtained after initial survey, and according to the inclusion criteria, 30 articles were selected for review. RESULTS AND CONCLUSION:Epidermal stem cells and other adult stem cells have been applied to treat wounds and other skin diseases. Epidermal stem cells are the crucial cell source of skin development, repair and remodeling. Epidermal stem cells are always in a resting state in vivo. Unless, skin injure or culture in vitro, cell division and proliferation will be significantly fastened. The stability of the epidermis mainly depends on the asymmetric division of a subpopulation, in which two daughter cells are produced, including one with characteristics of stem cells, and the other differentiated into transient amplifying cells that will be differentiated into post mitotic cells after a series of cell divisions (3-5 times). Afterwards, those post mitotic cells are developed into terminal differentiation cells on the basal layer, finally detach from the epidermis as dander. In addition, it is unclear whether epidermal factors are related to apoptosis, migration and differentiation in the process of wound repair and even under physiological conditions. Therefore, application of stem cells in wound healing requires a further discussion.     

壳聚糖-明胶海绵与脐带间充质干细胞修复皮肤伤口的差异

BACKGROUND: Umbilical cord mesenchymal stem cells possess multipotent differentiation and self-replication abilities, and can differentiate into osteoblasts, chondrocytes, smooth muscle cells and vascular endothelial cells, which contribute to reepithelialization and angiogenesis. OBJECTIVE: To compare effects of umbilical cord mesenchymal stem cells and chitosan-gelatin sponge in skin wound healing. METHODS: Thirty male Sprague-Dawley rats were equivalently randomized into model, chitosan-gelatin sponge and stem cell groups. 3×3 cm full-thickness skin defects were created on the rat dorsal area in each group, and 1 day later, model rats in each group were given intradermal injection of PBS, chitosan gel or umbilical cord mesenchymal stem cells, respectively, for successive 15 days. RESULTS AND CONCLUSION: Compared with the model group, the wound healing rate was higher, the epidermal thickness was decreased, and the collagen fiber area was larger in the chitosan-gelatin sponge and stem cell groups. Furthermore, the healing effect in the chitosan-gelatin sponge group was superior to that in the stem cell group. To conclude, both chitosan-gelatin sponge and umbilical cord mesenchymal stem cells, especially umbilical cord mesenchymal stem cells, can effectively repair skin defects.     

B超定位经皮肾穿活检在儿科的应用

本文报告一年来我院应用B型超声切面显象法,在儿科肾脏定位的20例次经皮肾活检的体会。一、方法 1.使用仪器:日立RT2000型或EUB40型B型超声波仪;探头:3.5MHz;Tru-Cut     

龙胆泻肝汤联合窄谱中波紫外线及夫坦乳膏外用治疗带状疱疹80例疗效观察

目的：探索龙胆泻肝汤联合窄谱中波紫外线（NB—UVB）治疗带状疱疹的疗效。方法：将160例带状疱疹患者被随机分为2组。治疗组80例，采用窄谱中波紫外线照射皮损，1次／d，照射剂量为0．5J／cm^2，同时给予口服龙胆泻肝汤，1剂／d，分2次服，外用夫坦乳膏，4次／d；对照组80例，给予口服盐酸伐昔洛韦片0．3g／次，2次／d，外用药、窄谱中波紫外线照射同治疗组；对于疼痛剧烈的患者同时给予双氯芬酸钠片75mg／次，1次／晚。治疗1周后观察疗效。结果：治疗组在止疱、结痂、止痛方面的疗效均明显优于对照组，经统计学处理差异具有显著性。结论：龙胆泻肝汤联合NB-UVB治疗带状疱疹可提高疗效，缩短临床痊愈时间。     

儿童横纹肌肉瘤预后的影响因素分析

目的:探讨儿童横纹肌肉瘤(RMS)的临床病理特征及预后影响因素。方法:回顾性分析我科93例RMS患儿的临床及生存资料,引入患儿性别、年龄、肿瘤大小、原发部位、组织学类型、COG-stage分期、COG-group分期、危险度分组和手术情况共9个因素。采用COX回归模型进行多因素分析,确立影响预后的因素,采用Kaplan-Meier生存曲线和Log-rank检验比较影响因素与生存率的关系。结果:全组1年、3年、5年生存率分别为90.3%、62.0%、43.1%,总体中位生存期为47.28个月。多因素分析显示组织学类型、原发部位、group分期和是否手术切除是儿童RMS预后的影响因素。生存分析提示不同组织学类型、原发部位、group分期及是否手术切除的预后差异均有统计学意义(均P<0.001)。结论:儿童RMS预后的影响因素有组织学类型、原发部位、group分期和是否手术切除,通过此分析能为预后判断和临床治疗强度的选择提供依据。