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101.
A 12-year-old girl with a history of fast myopia progression underwent advanced orthokeratology (ortho-k) treatment and suffered from recurrent lens binding and central corneal staining. The problem could not be fixed by lens fenestration and refitting with a less aggressive lens (three-zone ortho-k) design. After refitting with a lower target advanced ortho-k lens, these complications were no longer occurring, and the amount of power reduction was greater than expected considering the target designed for the refitted lenses. During the following 15 months of ortho-k lens wear, there was no clinically significant change to her refractive error. The patient and her parents were happy with the outcome, although the refractive error was not totally eliminated and she still needed to wear spectacles for clear vision. Possible etiologies of the complications are discussed. 相似文献
102.
W. Y. Zhang Research Fellow A. Li Wan Po Professor 《BJOG : an international journal of obstetrics and gynaecology》1998,105(7):780-789
Objective To quantify the efficacy and safety of naproxen, ibuprofen, mefenamic acid, aspirin and acetaminophen (paracetamol) in the treatment of primary dysmenorrhoea through a systemic overview of randomised controlled trials.
Methods MEDLINE, EMBASE and the Science Citation Index were searched for randomised controlled trials. Efficacy was assessed by measurement of pain relief, requirement for rescue analgesics, restriction of daily life and absence from work or school. The rate ratios of side effects were used to assess safety.
Results Fifty-six trials describing 55 comparisons of analgesics with placebo and 12 direct comparisons with other analgesics met our inclusion criteria. Women taking naproxen were over three times more likely to have at least moderate pain relief than those taking placebo. Ibuprofen, mefenamic acid and aspirin were also superior to placebo but acetaminophen was not. The requirement for rescue analgesics, restriction of daily life and absence from work or school were less frequent with naproxen and ibuprofen than placebo but not with aspirin or acetaminophen. Direct comparisons did not show any difference between naproxen and ibuprofen. Side effects occurred more frequently only with naproxen when compared with placebo.
Conclusion Naproxen, ibuprofen, mefenamic acid and aspirin are all effective in primary dysmenorrhoea. Ibuprofen appears to have the most favourable risk-benefit ratio. Acetaminophen appears to be less effective than nonsteroidal anti-inflammatory drugs, but there was only one trial meeting our inclusion criteria and further studies are required. 相似文献
Methods MEDLINE, EMBASE and the Science Citation Index were searched for randomised controlled trials. Efficacy was assessed by measurement of pain relief, requirement for rescue analgesics, restriction of daily life and absence from work or school. The rate ratios of side effects were used to assess safety.
Results Fifty-six trials describing 55 comparisons of analgesics with placebo and 12 direct comparisons with other analgesics met our inclusion criteria. Women taking naproxen were over three times more likely to have at least moderate pain relief than those taking placebo. Ibuprofen, mefenamic acid and aspirin were also superior to placebo but acetaminophen was not. The requirement for rescue analgesics, restriction of daily life and absence from work or school were less frequent with naproxen and ibuprofen than placebo but not with aspirin or acetaminophen. Direct comparisons did not show any difference between naproxen and ibuprofen. Side effects occurred more frequently only with naproxen when compared with placebo.
Conclusion Naproxen, ibuprofen, mefenamic acid and aspirin are all effective in primary dysmenorrhoea. Ibuprofen appears to have the most favourable risk-benefit ratio. Acetaminophen appears to be less effective than nonsteroidal anti-inflammatory drugs, but there was only one trial meeting our inclusion criteria and further studies are required. 相似文献
103.
吗啡对机械通气病人的应用 总被引:1,自引:0,他引:1
为获得病人在接受呼吸机期间充分的镇静、良好的耐管并与呼吸机合拍达到满意的治疗效果,对60例不同年龄的患者在进行呼吸机支持治疗期间,采用平均045mg/(kgd)的吗啡量持续微量泵静脉注入,间断辅助安定的方法.用药后连续2h观察血压、心率、呼吸、意识等变化.结果:在用药期间病人血压、心率、呼吸平稳,保持清醒,安静耐管,解决了病人与呼吸机拮抗的矛盾.结果表明:该法在临床上有广泛使用价值 相似文献
104.
计算机在医学领域中的应用及展望 总被引:2,自引:0,他引:2
对计算机在医学文献检索、医学统计软件包的编制、疾病诊断、医院管理等医学领域中的应用作了简要的综述,并对未来的发展进行了预测。 相似文献
105.
对何首乌伪品芭蕉块根的药材性状、组织特征、成分、理化薄层等进行了实验研究。结果证明伪品何首乌是芭蕉科植物芭蕉地下块茎经人工制模而成. 相似文献
106.
银耳多糖、银耳孢子多糖及黑木耳多糖的抗溃疡作用 总被引:11,自引:0,他引:11
银耳多糖、银耳孢子多糖及黑木耳多糖以每天70mg/kg灌胃2d,均明显抑制大鼠应激型溃疡的形成;以每天165mg/kg灌胃124,能促进醋酸型胃溃疡的愈合。对胃酸分泌和胃蛋白酶活性无明显影响。本研究表明,这三种多糖均有抗溃疡作用。 相似文献
107.
视盘血管炎——关于混合型的研讨 总被引:2,自引:0,他引:2
对60例(63眼)视盘血管炎的临床分型进行了探讨,结果表明,除分为Ⅰ、Ⅱ两型外,尚存在混合型,当视盘睫状血管炎性病变波及中央静脉,或两个血管系统同时受炎症侵犯时,即可再现混合型的临床表现,视盘明显水肿,视网膜静脉迂张,散在渗出,出血,动脉狭细。眼底荧光血管造影可见视盘荧光早期充盈明显迟缓,后期渗漏面积〉2.0PD,视网膜循环时间延长,混合型兼有Ⅰ,Ⅱ两型的临床特征,应作为一个独立类型存在,同时观察 相似文献
108.
109.
110.
目的 探讨癌胚抗原相关细胞黏附分子(CEACAM1)源性多肽KM17对血小板聚集、释放、黏附功能的影响。方法 采用血小板聚集仪观察多肽KM17对凝血酶、胶原、花生四烯酸(AA)、二磷酸腺苷(ADP)等激动剂诱导的血小板聚集的影响;流式细胞术观察多肽KM17对ADP激活血小板后P-选择素释放的影响;显微镜下观察多肽KM17对血小板静态黏附于胶原基质的影响。结果 多肽KM17能显著促进ADP诱导的血小板聚集且呈剂量依赖(P <0.05),而对AA、胶原及凝血酶诱导的血小板聚集差异均无统计学意义(P>0.05);此外,多肽KM17对ADP激活血小板后P-选择素释放及血小板静态黏附于胶原基质的差异也无统计学意义(P>0.05)。结论 多肽KM17可明显促进ADP诱导的血小板聚集,但对ADP活化血小板后P-选择素释放及血小板静态黏附于胶原基质未见明显作用。 相似文献