CT造影剂碘海醇注射液的制备及动物实验

本文报道了非离子型Ｘ－ＣＴ造影剂碘海醇注射液的制备及动物实验结果。磺海醇的最大吸收波长λ＿（ｍａｘ）为２４４ｎｍ。讨论了温度、浓度对磺海醇溶液粘度的影响：粘度随温度的升高而下降，呈负线型相关；粘度随浓度（Ｃ）升高而激剧升高，与浓度的四次方呈线性相关：Ｖ＿（３７℃）＝４７２．５８９［Ｃ］￣４＋１．１２１（ｒ＝０．９９７７）Ｖ＿（３０℃）＝６６３．８１３［Ｃ］￣４＋１．１５２（ｒ＝０．９９９６）Ｖ＿（２０℃）＝１０８２．９５３［Ｃ］￣４＋１．４３３（ｒ＝０．９９８２）使用该注射液进行狗的造影实验，获得了清晰的造影图像。     

铅性肾病的流行病学分析

我们检查了铅接触人员１０２３名，发现铅性肾病８４例，患病率８．２％。女性３４例（７．２％），男性５０例（９％），男女铅性肾病患病率无显著性差异。印刷厂空气铅浓度平均０．００６９ｍｇ／ｍ３，蓄电池厂为０．１００５ｍｇ／ｍ３，铅矿为０．５ｍｇ／ｍ３。铅性肾病患病率分别为４．７３％，８．３％和２８．５７％（Ｐ＜０．００５）。分析铅性肾病患病率与年龄和铅接触年限的关系。年龄小于３０岁，～４０岁，～５０岁和大于５０岁者，铅性肾病患病率分别为５．５％，８．６％，１２．１％，和１５．６％（Ｐ＜０．０５）。铅接触年限小于１０年，～２０年和大于２０年者，铅性肾病患病率分别为６．６％，９．９％和１３．１％（Ｐ＜０．０５）。     

植物神经癫痫52例脑电图分析

报道52倒6个类型植物神经癫痫,重点分析了脑电图的变化,脑电图异常率100％,69.4％的病例出现两侧阵发性4～7Hzθ节律及6和14Hz阳性棘波,提示中线深部有功能紊乱,亦支持丘脑及脑干部有病变。此外蝶骨电极能提高脑电图对本病的阳性诊断率,值得采用。本文证明脑电图对植物神经性癫痫与非癫痫的鉴别诊断,具有肯定的价值。     

内皮素鞘内注射后的脊髓形态学观察

对18只大鼠进行内皮素脊髓鞘内注射,观察及记录大鼠后肢功能状态,并将18只大鼠分为3个不同的时间处死,进行病理形态学观察。结果表明:3组均表现缺血缺氧病理改变。2及4h实验组病变重于30min实验组。脊髓下胸段、腰段病变重于颈段及骶尾段。同时发现,大鼠后肢的功能状态与其脊髓相应的病理形态学变化不呈正比。     

生精丸治疗男性不育60例临床研究

目的观察生精丸对男性不育的治疗作用.方法选择120例男性不育患者,随机分为治疗组和对照组.每组60例,分别给予生精丸和五子衍宗丸治疗.治疗前后以WLJY-9000伟力彩色精子质检系统进行精液参数分析,并检测血液睾酮(T)水平,同时观察病人服用生精丸期间有无明显不良反应.结果治疗组精子密度、活率、活力以及运动参数和睾酮水平等指标均明显高于对照组(P＜0.05),痊愈率、显效率及总有效率亦高于对照组(P＜0.05),且服药期间无明显的不良反应.结论生精丸有从整体上纠正精液异常的功效,能使病人精子数量、质量、睾酮水平得到提高.     

白鲜皮汤治疗湿热性疮疡18例

笔者近年来用“白鲜皮汤”治疗黄水疮、湿疹、下肢静脉曲张伴溃疡症等 1 8例 ,收到满意效果 ,现报道如下。1　一般资料本组 1 8例 ,男 1 6例 ,女 2例 ;最大年龄 4 3岁 ,最小年龄9岁 ,以 1 4～ 4 0岁青壮年多见 ;病程最长 5a,最短 1 5d ,大多数患者疡面流黄水、溃烂、瘙痒。本组     

Comparison of Minimum Alveolar Concentration between Intravenous Isoflurane Lipid Emulsion and Inhaled Isoflurane in Dogs

Background: As in inhaled isoflurane anesthesia, when isoflurane lipid emulsion (ILE; 8%, vol/vol) is intravenously administered, the primary elimination route is through the lungs. This study was designed to determine the minimum alveolar concentration (MAC) and the time course of washout of isoflurane for intravenously infused ILE by monitoring end-tidal isoflurane concentration.

Methods: Twelve healthy adult mongrel dogs were assigned randomly to an intravenous anesthesia group with 8% ILE or to an inhalation anesthesia group with isoflurane vapor. An up-and-down method and stimulation of tail clamping were used to determine MAC of 8% ILE by intravenous injection in the intravenous anesthesia group and MAC by the inhaled approach in the inhalation anesthesia group, respectively. Isoflurane concentration and partial pressure in end-tidal gas, femoral arterial blood, and jugular venous blood were measured simultaneously just before each tail clamping and during washout.

Results: The induction time in the intravenous anesthesia group (105 +/- 24 s) was shorter than that in the inhalation anesthesia group (378 +/- 102 s; P < 0.01). MAC of 8% ILE by intravenous injection (1.12 +/- 0.18%) was significantly less than MAC by the inhaled approach (1.38 +/- 0.16%; P < 0.05). No significant difference was found between the two groups in the time course of washout of isoflurane.