TCT联合病理活检及DNA倍体分析在宫颈癌筛查中的价值

目的 探讨TCT技术、病理活检和DNA倍体分析在宫颈癌筛查中的应用价值.方法 随机抽取门诊就诊病人行TCT检查和DNA倍体分析.诊断阳性者,全部在阴道镜下活检,行LEEP术后标本与阴道镜下活检结果进行对照.结果 除12例不满意标本外,TCT异常者检出率为8.43％;其中ASCUS占5.03％,LSIL占1.72％,HSIL占1.59％,SCC占0.09％.LEEP术前与术后诊断结果比较,差别有显著性.DNA倍体分析异常者4.46％.结论 细胞学筛查与病理活检及DNA倍体分析联合应用,在保证筛查的敏感性的同时能明显提高子宫颈癌前病变及宫颈癌筛查的特异性,提高检出率.     

介绍一种处理陈旧褪色切片的新技术

<正>在临床病理工作中,由于病理诊断工作的需要,常常遇到要查阅借调以往陈旧组织切片的情况。但由于时间的关系,这些切片常发生褪色,且大多是苏木素颜色减退,有些切片甚至完全褪色,从而严重影响病理诊断质量。笔者通过长期实践摸索并查阅了大量文献资料,对一些年代久远的陈旧褪色切片进     

Surgical pathologic findings of extratemporal-based intractable epilepsy: a study of 133 consecutive resections

BACKGROUND: Surgical management of intractable epilepsy continues to be important in select cases to achieve seizure control. DESIGN: This study retrospectively reviews the pathologic findings in 133 consecutive cases of extratemporal lobe epilepsy experienced during a 17-year period. RESULTS: The study group consists of 133 patients (78 males) who underwent extratemporal lobe resection for epilepsy at a mean age of 21.1 years (range, 3 months to 57 years). In 50 patients (37.6%), cortical dysplasia (neuronal migration abnormalities) was identified. The most common patterns of dysplasia observed included diffuse architectural disorganization in 46 cases, neuronal cytomegaly in 30 cases, increased numbers of molecular layer neurons in 30 cases, and balloon cells in 18 cases. Tumors were identified in 37 cases (27.8%) and included 13 astrocytomas, 7 gangliogliomas, 6 dysembryoplastic neuroepithelial tumors, 6 glioneuronal hamartomas, 4 oligodendrogliomas, and 1 oligoastrocytoma (mixed glioma). Twenty-four resections (18%) showed evidence of remote ischemic damage or infarct. Neuronal heterotopia was identified in 59 resection specimens (44.4%). Other less common findings included vascular malformations in 4 patients (3.0%), Sturge-Weber malformations in 3 patients (2.3%), and Rasmussen encephalitis in 2 patients (1.5%). Two patients were known to have tuberous sclerosis. In 23 resection specimens (17.3%), no significant pathologic finding was identified. Coexistent cortical dysplasia and tumor were seen in 10 cases and coexistent dysplasia and infarct or remote ischemic damage in 11 cases. CONCLUSION: This series demonstrates that most patients with extratemporal lobe epilepsy have significant histopathologic findings, which most frequently include cortical dysplasia, tumor, or evidence of remote ischemic damage or infarct. Coexistent pathologic findings were present in a significant minority of cases (16.5%).     

有限切开显露法术中诊断下胫腓损伤的应用

踝部骨折是骨科常见的创伤,术中一般使用Hook test实验及外旋应力实验来判断是否存在下胫腓联合损伤,本科室应用有限切开显露法诊断及治疗下胫腓联合损伤得到良好疗效。     

"六补"度过"多事之秋"

人们经过炎热的夏天,身体消耗大,体内的营．养物质相对缺乏,所以会出现体重减轻、倦怠乏力、食欲降低等体虚症状,此时调养一下身体很有必要。根据中医“虚则补之”的原则,早秋进补对恢复体力、提高身体的抗病能力有积极作用。     

MRI和超声在小儿阑尾炎诊断方面的前瞻性比较

正摘要目的前瞻性比较非增强MR成像和超声在小儿阑尾炎诊断方面的差异。材料与方法本研究符合HIPAA要求,经过研究机构伦理委员会批准,并获得病人家长或监护     

040 体育锻炼与心理健康状况

[英]/Hassmen P…//Prev Med .-2000,30(1).-17～25 　　背景经常锻炼被认为是对身体有益的健康行为,同时它还可以带来心理健康.本文的研究目的是为了揭示在一个较大的人群基础样本中,体育锻炼频率与心理健康状况测量值之间的联系. 　　方法在芬兰心血管疾病危险因子调查中,有3 403名年龄在25～64岁参与者完成了问卷调查,其中男性1 547人;女性1 856人.他们除回答有关健康习惯、自我感觉健康及适合状况外,还完成了贝克压抑调查(Beck Depression Inventory)、易怒度、疑人度及协调感调查. 　　结果本横断面调查结果提示,每周至少锻炼2～3次的个体比那些较少锻炼甚至不锻炼的个体,其压抑、易怒、疑人及紧张程度明显要低.而且,经常锻炼发觉其健康及适宜状态比较少锻炼者要好.每周至少锻炼2次人群比较少锻炼人群协调感要高,社会和谐感要强. 　　结论在运用心理调查变量测量后,心理健康状况的提高与经常锻炼相关. （艾宗波摘 周雪平校）