昏迷病人意识恢复初期的情感需要

昏迷病人意识恢复初期的情感需要潘德玲，张佳瑞，刘丽卿珠江医院神经外科昏迷病人意识恢复初期呈朦胧状态，多有明显的躁动，大声喊叫，四肢乱舞，企图挣扎坐起，拔除各种引流管或输液管，挣脱或挣断束缚带，呼吸、心率、血压较安静状态时明显增加或升高。本文旨在探讨有...     

星形细胞瘤的胶质纤维酸性蛋白和波形蛋白免疫组织…

应用图像分析仪对２５例Ⅱ－Ⅳ级星形细胞瘤进行ＧＦＡＰ，ＶＩＭ免疫组织化学定量研究。结果表明：２５例星形细胞瘤全部呈ＧＦＡＰ，ＶＩＭ阳性反应，ＧＦＡＰ，ＶＩＭ免疫反应强度与肿瘤组织的分化程度有关，高分化的星形细胞瘤（Ⅱ级），ＧＦＡＰ反应强，ＶＩＭ反尖弱，而低分化的星形细胞瘤（Ⅲ，Ⅳ级）中，ＶＩＭ反应强，ＧＦＡＰ反应弱，即ＧＦＡＰ与肿瘤恶性度负相关；ＶＩＭ与肿瘤组织恶性程度正相关。     

灭滴灵治疗阿米巴肝脓肿引起中毒性黄疸型肝炎1例

患者,男,51岁,农民。1989年11月10日起发热、寒战,体温38.5℃。皮肤巩膜进行性黄染,5天后伴右上腹痛。查体:肝肿大右肋下9 cm,触痛明显,血WBC38×10~9/L,N90％、L10％,TTT、TFT、SGPT均正常。HBsAg(-)。总胆红素102.6μmol/L,Ⅱ 58单位。肝CT和肝B超均显示肝右叶14cm×16cm液性占位病变。4次肝穿刺总计抽出巧克力色脓液1600ml,细菌培养阴性。口服灭滴灵600mg 1日3次,连服42天,继以400mg 1日3次维持25天。用药3天后体温即降至正常,肝痛缓解,1周后黄疸明显减退,肝脏缩小,右肋下4 cm,脓腔减至8.3cm×6.3cm,血WBC9×10~9/L,住院50     

急性心肌梗塞合并心源性休克治疗体会

本院自89年以来在收治的37例AMI中并发心源性休克者8例。8例患者在对症治疗的同时,均联用硝普纳和多巴胺静点,与以前惯用极化液疗法对比,病死率明显降低,今就治疗体会报道如下:1 临床资料8例患者,男5例,女3例,年龄最大80岁,最小43岁,平均年龄约63岁,60岁以上5人。多在得病后5～10小时入院。既往有冠心病史者5例,其中有陈旧性心肌梗塞者1例。     

吗啡预处理-后处理对大鼠离体心脏缺血再灌注损伤的影响

Objective To evaluate the effects of morphine preconditioning-postconditioning on ischemia-reperfusion (I/R) injury in isolated rat hearts. Methods Male SD rats weighing 180-200 g were killed after intraperitoneal injection of heparin 500 U/kg. The hearts were immediately removed and perfused in a Langendorff apparatus with K-H solution gassed with 95%O2-5%CO2 .HR and left ventricular systolic pressure (LVSP) were measured from a fluid-filled latex balloon in the left ventricle. Global myocardial ischemia was induced by interrupting perfusion for 45 min followed by 60 min reperfusion. Forty isolated rat hearts were randomly divided into 5 groups (n = 8 each): group 1 (I/R); group II morphine preconditioning (M1 ); group Ⅲ morphine postconditioning (M2); group IV M1 + M2; group V 5-hydroxydecanoate (5-HD) + M2. Group M1 was perfused with K-H solution containing morphine 3.0 μmol/L for 20 min 30 min before ischemia followed by 10 min normal K-H solution perfusion. Group M2 was perfused with K-H solution containing morphine 3.0 μmol/L for 10 min at the beginning of reperfusion followed by 50 min normal K-H solution perfusion. Group 5-HD + M2 was perfused with K-H solution containing morphine 3.0 μmol/L+ 5-HD 10-4 mmol/L for 10 min at the beginning of reperfusion followed by 50 min normal K-H solution perfusion. Myocardial CK-MB activity was measured and myocardial infarct size (IS/AAR) detennined (by 2,3,5-triphenyl tetrazolium staining) at the end of 60 min reperfusion. Results The preconditioning, postconditioning and combination of preconditioning and postconditioning with morphine 3.0 μmol/L perfusion for 10 min all provided cardio-protective effects in terms of IS/AAR and myocardial activation of CK-MB. Conclusion Although the combination of morphine preconditioning and postconditioning can protect the heart against I/R injury, the effects are similar to those of either of them alone, and the reason may be that either of them alone protects the heart against I/R injury via activating mitoKATP .     

532nm倍频激光治疗眼底病初步报告

我们自2000年12月开始采用美国IRIS公司OculigntGL-532nm倍频激光治疗眼底病137例(175只眼),取得初步效果,现报道如下。1 资料与方法1.1 一般资料:糖尿病视网膜病变38例(76只眼)。男18例,女20例。中心性浆液性脉络膜视网膜病变49例(49只眼),男38例,女11例。视网膜静脉周围炎7例(7只眼),男5例,女2例。视网膜静脉阻塞43例(3只眼),男18例,女25例。